This chapter describes the outcome of the creation of an eCare Network for frail elderly people in 2005. This was developed over the years as a network of citizens, associations, institutions, and professionals, providing a relational and support ecosystem to frail elderly people. The issue of financial sustainability of the health and social welfare system, in the phase of ongoing demographic revolution, has stimulated the creation of a service that aims to encourage the permanence of frail elderly citizens at home to prevent the onset of frailty or dependency and to improve their quality of life by fighting social isolation through the use of appropriate IT technologies. Community-based voluntary associations also play a key role in the eCare Network for the frail elderly. Finally, in addition to a detailed description of the activities that have been put in place, the service outcomes, innovations, and prospects for further development are illustrated.