scholarly journals Problem solving treatment and group psychoeducation for depression: multicentre randomised controlled trial

BMJ ◽  
2000 ◽  
Vol 321 (7274) ◽  
pp. 1450-1450 ◽  
Author(s):  
C. Dowrick ◽  
G. Dunn ◽  
J. L. Ayuso-Mateos ◽  
O. S. Dalgard ◽  
H. Page ◽  
...  
2011 ◽  
Vol 199 (4) ◽  
pp. 310-316 ◽  
Author(s):  
Simon Hatcher ◽  
Cynthia Sharon ◽  
Varsha Parag ◽  
Nicola Collins

BackgroundPresentations to hospital with self-harm are common, associated with suicide and have an increased mortality, yet there is no accepted effective intervention.AimsTo investigate whether problem-solving therapy would improve outcomes in adults presenting to hospital with self-harm, compared with usual care.MethodA Zelen randomised controlled trial was conducted in four district health boards in New Zealand. A second hospital presentation with self-harm at 1 year for all episodes, plus separate comparisons of first-time and repeat presentations at the index episode, were the a priori primary outcomes. The trial registration number was ACTRN12605000337673.ResultsIn an intention-to-treat analysis of all randomised patients (n = 1094) there was no significant difference at 12 months in the proportion of people who had presented again with self-harm when comparing all episodes (intervention 13.4%, usual care 14.1%; relative risk reduction RR = 0.05, 95% CI −0.28 to 0.30, P = 0.79) or where the index episode was the first episode (intervention 13.4%, usual care 9.4%, RR =–0.42, 95% CI −1.17 to 0.08, P = 0.37). Where the index episode was repeated self-harm, those who received therapy were less likely to present again with self-harm (intervention 13.5%, usual care 22.1%, RR = 0.39, 95% CI 0.07 to 0.60, number needed to treat 12, P = 0.03).ConclusionsProblem-solving therapy is not recommended for everyone who presents to hospital with self-harm. Among adults with a history of self-harm it may be an effective intervention.


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