scholarly journals Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database survey

BMJ ◽  
2012 ◽  
Vol 344 (jan03 1) ◽  
pp. d7762-d7762 ◽  
Author(s):  
I. Ahmed ◽  
A. J. Sutton ◽  
R. D. Riley
Keyword(s):  
Publication Bias ◽  
Selection Bias ◽  
Individual Participant Data ◽  
Individual Participant ◽  
Meta Analyses ◽  
Bias Selection

scholarly journals Arm Based on LEg blood pressures (ABLE-BP): can systolic leg blood pressure measurements predict systolic brachial blood pressure? Protocol for an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e040481
Author(s):  
Sinead T J McDonagh ◽  
James P Sheppard ◽  
Fiona C Warren ◽  
Kate Boddy ◽  
Leon Farmer ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Public Involvement ◽  
Meta Analysis ◽  
Patient And Public Involvement ◽  
Prognostic Models ◽  
Individual Participant Data ◽  
Dissemination Strategy ◽  
Cross Sectional ◽  
Individual Participant ◽  
Meta Analyses

IntroductionBlood pressure (BP) is normally measured on the upper arm, and guidelines for the diagnosis and treatment of high BP are based on such measurements. Leg BP measurement can be an alternative when brachial BP measurement is impractical, due to injury or disability. Limited data exist to guide interpretation of leg BP values for hypertension management; study-level systematic review findings suggest that systolic BP (SBP) is 17 mm Hg higher in the leg than the arm. However, uncertainty remains about the applicability of this figure in clinical practice due to substantial heterogeneity.AimsTo examine the relationship between arm and leg SBP, develop and validate a multivariable model predicting arm SBP from leg SBP and investigate the prognostic association between leg SBP and cardiovascular disease and mortality.Methods and analysisIndividual participant data (IPD) meta-analyses using arm and leg SBP measurements for 33 710 individuals from 14 studies within the Inter-arm blood pressure difference IPD (INTERPRESS-IPD) Collaboration. We will explore cross-sectional relationships between arm and leg SBP using hierarchical linear regression with participants nested by study, in multivariable models. Prognostic models will be derived for all-cause and cardiovascular mortality and cardiovascular events.Ethics and disseminationData originate from studies with prior ethical approval and consent, and data sharing agreements are in place—no further approvals are required to undertake the secondary analyses proposed in this protocol. Findings will be published in peer-reviewed journal articles and presented at conferences. A comprehensive dissemination strategy is in place, integrated with patient and public involvement.PROSPERO registration numberCRD42015031227.

scholarly journals An individual participant data (IPD) meta-analysis on the attachment network to multiple caregivers

2020 ◽  
Author(s):  
Or Dagan ◽  
Pasco Fearon ◽  
Carlo Schuengel ◽  
Marije Verhage ◽  
Glenn I. Roisman ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Developmental Outcomes ◽  
Research Synthesis ◽  
Individual Participant Data ◽  
Attachment Relationship ◽  
Attachment Research ◽  
Individual Participant ◽  
The Subject ◽  
Meta Analyses

Since the seminal 1992 paper by van IJzendoorn, Sagi, and Lambermon, putting forward the “The multiple caretaker paradox”, relatively little attention has been given to the potential joint effects of the role early attachment network to mother and father play in development. Recently, Dagan and Sagi-Schwartz (2018) have published a paper that attempts to revive this unsettled issue, calling for research on the subject and offering a framework for posing attachment network hypotheses. This Collaboration for Attachment Research Synthesis project attempts to use an Individual Participant Data meta-analyses to test the hypotheses put forward in Dagan and Sagi-Schwartz (2018). Specifically, we test (a) whether the number of secure attachments (0,1, or 2) matter in predicting a range of developmental outcomes, and (b) whether the quality of attachment relationship with one parent contributes more than the other to these outcomes.

scholarly journals Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study

BMJ ◽  
2015 ◽  
Vol 350 (mar06 6) ◽  
pp. h1088-h1088 ◽  
Author(s):  
C. L. Vale ◽  
L. H. M. Rydzewska ◽  
M. M. Rovers ◽  
J. R. Emberson ◽  
F. Gueyffier ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Systematic Reviews ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Descriptive Study ◽  
Individual Participant Data ◽  
Individual Participant ◽  
Meta Analyses

scholarly journals How systematic reviews and meta-analyses based on individual participant data can inform trial design and conduct

Trials ◽  
2013 ◽  
Vol 14 (S1) ◽  
Author(s):  
Jayne Tierney ◽  
Claire Vale ◽  
Jean-Pierre Pignon ◽  
Francois Gueffyier ◽  
Lisa Askie ◽  
...  
Keyword(s):  
Systematic Reviews ◽  
Trial Design ◽  
Individual Participant Data ◽  
Individual Participant ◽  
Meta Analyses

scholarly journals Individual participant data meta-analyses compared with meta-analyses based on aggregate data

Trials ◽  
2011 ◽  
Vol 12 (S1) ◽  
Author(s):  
Catrin Tudur Smith ◽  
James Oyee ◽  
Maura Marcucci ◽  
Maroeska Rovers ◽  
Alfonso Iorio ◽  
...  
Keyword(s):  
Aggregate Data ◽  
Individual Participant Data ◽  
Individual Participant ◽  
Meta Analyses

scholarly journals Retrieval of Individual Participant Data for Exercise Meta-Analyses May Not Be Worth the Time and Effort

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
George A. Kelley ◽  
Kristi S. Kelley
Keyword(s):  
Logistic Regression ◽  
Rheumatic Diseases ◽  
Gold Standard ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Individual Participant Data ◽  
Individual Participant ◽  
Using Data ◽  
Meta Analyses

Purpose. While individual participant data (IPD) meta-analyses are considered the gold standard for meta-analysis, the feasibility of obtaining IPD may be problematic.Methods. Using data from a previous meta-analysis of 29 studies on exercise in adults with arthritis and other rheumatic diseases, the percentage of studies in which useable IPD was provided was calculated.Results. Eight of 29 authors (28%, 95% CI = 11% to 44%) provided IPD. Using logistic regression, neither year of publication (odds ratio = 1.05, 95% CI = 0.90 to 1.27,p=0.58) nor country (odds ratio = 1.36, 95% CI = 0.20 to 10.9,p=1.00) was significantly associated with the obtainment of IPD.Conclusions. The retrieval of IPD for exercise meta-analyses may not be worth the time and effort. However, further research is needed before any final recommendations can be made.

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