Antiretroviral treatment can reduce the risk of HIV transmission between male partners to ‘zero’

BMJ ◽  
2019 ◽  
pp. l4915
Author(s):  
Rob Cook ◽  
Peter Davidson ◽  
Rosie Martin ◽  
Keyword(s):  
Antiretroviral Therapy ◽  
Observational Study ◽  
Antiretroviral Treatment ◽  
Prospective Observational Study ◽  
Hiv Transmission ◽  
Hiv Positive ◽  
Male Partners ◽  
Patient Benefit ◽  
Gay Couples ◽  
Condomless Sex

The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funded by the NIHR Research for Patient Benefit Programme (project number PB-PG-1013-32069).To read the full NIHR Signal, go to https://discover.dc.nihr.ac.uk/content/signal-000785/antiretroviral-treatment-can-reduce-the-risk-of-hiv-transmission-between-male-partners-to-zero

Correlates of HIV-Positive Fathers’ Involvement in Prevention of Motherto- child Transmission Programs in Northern Nigeria

2020 ◽  
Vol 18 (6) ◽  
pp. 443-457
Author(s):  
Zubairu Iliyasu ◽  
Hadiza S. Galadanci ◽  
Bashir Muhammad ◽  
Fatima Z. Yadudu ◽  
Aminatu A. Kwaku ◽  
...  
Keyword(s):  
Condom Use ◽  
Hiv Transmission ◽  
Male Partner ◽  
Tertiary Hospital ◽  
Consistent Condom ◽  
Hiv Positive ◽  
Northern Nigeria ◽  
Male Partners ◽  
Logistic Regression Models ◽  
Paternal Education

Background: The involvement of men in the prevention of mother-to-child HIV transmission (PMTCT) programs could accelerate the elimination of vertical transmission. Yet, little research has focused on HIV-positive male partners. This study determined predictors of male partners’ PMTCT knowledge and involvement in a tertiary hospital in northern Nigeria. Methods: A clinic-based sample of 401 HIV-positive male partners of women who delivered within 12 months prior were interviewed using structured questionnaires. PMTCT knowledge and involvement scores were computed. Adjusted odd ratios (AOR) for predictors were derived from multivariate logistic regression models. Results: The proportion of respondents with adequate PMTCT knowledge was 40.9%. Less than half (43.6%) of the respondents participated in PMTCT, with median involvement score of 2.00 (interquartile range, IQR = 0, 5.0). One quarter of respondents (25.7%, n =103) reported >1 sex partners, 10.5% consistently used condoms, and 20.7% had disclosed to all partners. Father’s involvement in PMTCT was predicted by paternal education (AOR = 0.30; 95% Confidence Interval (CI): 0.12-0.77, no formal vs. post-secondary), HIV-positive child (AOR = 3.85; 95%CI: 1.41-10.54, yes vs. no), treatment duration (AOR = 4.17; 95%CI: 1.67-10.41, ≤1 vs. ≥10 years), disclosure to partner(s) (AOR = 1.21; 95%CI: 1.15-3.52, ‘disclosed to all’ vs. ‘not disclosed’), condom use (AOR = 5.81; 95%CI: 3.07-11.0, always vs. never), and PMTCT knowledge (AOR = 0.62; 95%CI: 0.31-0.92, inadequate versus adequate). Conclusion: The involvement of fathers in HIV PMTCT programs was low and predicted by paternal education, HIVpositive child, duration of antiretroviral treatment, disclosure to partner, consistent condom use, and level of PMTCT knowledge. Our findings will inform the development of policies to increase male partner involvement in PMTCT in Nigeria.

scholarly journals Systematic Review of HIV Transmission between Heterosexual Serodiscordant Couples where the HIV-Positive Partner Is Fully Suppressed on Antiretroviral Therapy

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e55747 ◽  
Author(s):  
Mona R. Loutfy ◽  
Wei Wu ◽  
Michelle Letchumanan ◽  
Lise Bondy ◽  
Tony Antoniou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Hiv Transmission ◽  
Hiv Positive ◽  
Serodiscordant Couples

scholarly journals HIV-positive patients’ perceptions of care received at a selected antiretroviral therapy clinic in Vhembe district, South Africa

2016 ◽  
Vol 8 (2) ◽  
Author(s):  
Tshifhiwa V. Ndou ◽  
Sonto M. Maputle ◽  
Patrone R. Risenga
Keyword(s):  
Health Care ◽  
Antiretroviral Therapy ◽  
Antiretroviral Treatment ◽  
Care Process ◽  
Hiv Positive ◽  
Process Of Care ◽  
Individual Interviews ◽  
Professional Workers ◽  
Open Coding ◽  
Vhembe District

Background: Patients’ experiences are a reflection of what has happened during the care process and, therefore, provide information about the performance of health care professional workers. They refer to the process of care provision at the antiretroviral therapy (ART) sites.Aim and setting: This article explored the perceptions of HIV-positive patients of care received at the Gateway Clinic of the regional hospital that provides antiretroviral treatment in the Vhembe district.Methods: A qualitative, explorative and descriptive design was used. A non-probability, convenient sampling method was used to select 20 HIV-positive patients who were above 18 years of age. In-depth individual interviews were used to collect data. Data were analysed through Tech’s open coding method.Results: One theme and two sub-themes emerged, namely positive experiences related to the environment and attitudes of health professionals, and negative experiences concerning the practices by health care providers.Conclusion: Patients’ perceptions of quality of, and satisfaction with, health care may affect health outcomes. Recommendations are made to consider, practice and strengthen the protocols, the standard operating procedures and the principles of infection control in the health facilities.Keywords: Human Immunodeficiecy Virus, Antiretroviral Treatment, HIV positive, Limpopo

scholarly journals Magnitude of antiretroviral treatment failure and associated factors among adult HIV-positive patients in Harar public hospitals, Eastern Ethiopia

2020 ◽  
Vol 8 ◽  
pp. 205031212090607
Author(s):  
Rahel Feleke ◽  
Biftu Geda ◽  
Kedir Teji Roba ◽  
Fitsum Weldegebreal
Keyword(s):  
Antiretroviral Therapy ◽  
Treatment Failure ◽  
Associated Factors ◽  
Antiretroviral Treatment ◽  
Public Hospitals ◽  
World Health ◽  
Hiv Positive ◽  
Therapy Failure ◽  
Eastern Ethiopia ◽  
Antiretroviral Treatment Failure

Background: Antiretroviral treatment failure occurred when the antiretroviral regimen is unable to control HIV infection. There is no information on antiretroviral therapy failure in this study area. Objective: The aim of this study was to assess the magnitude and associated factors of antiretroviral therapy failure among HIV-positive adult patients in Harar public hospitals from January to February 2018. Methods: An institution-based cross-sectional study was conducted using chart review data from February 2005 to July 2017. Systematic sampling technique was used to include a sample of 1094 patient charts. Data were analyzed by Statistical Package for Social Sciences version 20.0. Statistical significance was considered at p < 0.05. Results: The prevalence of first-line antiretroviral treatment failure was 21% (95% confidence interval = 18.3–23.5). Being male in sex, age of 45–54 years, patients with World Health Organization stages 3 and 4 during antiretroviral therapy initiation, a baseline CD4 count <100 cells/mm3, poor drug adherence, and on antiretroviral therapy follow-up for ⩾25 months were predictors of antiretroviral treatment failure. Conclusion: In this study, the rate of antiretroviral treatment failure is relatively high. Therefore, the concerned body should pay attention to the predictors to reduce the risk of treatment failure among this study group.

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