▾ Securon SR: sustained-release verapamil

1987 ◽  
Vol 25 (12) ◽  
pp. 47-48

Verapamil was the first calcium antagonist in clinical use and its value in the treatment of angina, hypertension and cardiac arrhythmias is well established.1 Standard verapamil tablets have to be taken twice or three times daily but now a scored sustained-release (s/r) tablet containing 240mg verapamil (Securon SR - Knoll) has been licensed for the treatment of mild to moderate hypertension. A single dose is claimed to lower blood pressure for 24 hours. As we have noted before,2 the pros and cons of s/r products need careful assessment.

1929 ◽  
Vol 25 (2) ◽  
pp. 229-229

According to W. Grоssmann'y (Med. Klinik, 1928, No. 12) for the treatment of hypertension, it is undoubtedly possible to recommend the named remedy, containing the active components of the plant Viscum album (mistletoe). In cases of mild and moderate hypertension of various origins, by compression up to 200 mlm., Taking the drug 20 drops three times a day, most often in 8-14 days, a rapidly advancing and slowly increasing pressure drop by 20-40 mlm., In parallel with which significantly painful subjective disorders such as flickering before the eyes, tinnitus, hot flashes, dizziness and headaches also subside. In more severe cases, with a pressure of more than 200, mainly with advanced sclerosis of the arteries or kidneys, the decrease in pressure is not so constant, it is often not observed at all, but subjective disorders are often significantly improved here. The hood lasts indefinitely, is constant in its action and is cheap (2 marks for a glass of 30 kb. Ctm.). Therefore, it deserves attention, and with the availability of other drugs to lower blood pressure, such as drugs from the gonads yogimbin, vasotonin (yogimbin with urethane), nitrites, nitroscleran and aorthalgin (Na nitrosum plus NaJ).


BMJ ◽  
1986 ◽  
Vol 293 (6541) ◽  
pp. 266-267 ◽  
Author(s):  
M R Lee ◽  
J A Critchley ◽  
R F Jeffrey ◽  
S Freestone ◽  
T M MacDonald

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