scholarly journals PMO-114 Low CD39 expression marks severe regulatory t cell impairment in patients with autoimmune sclerosing cholangitis

Gut ◽  
2012 ◽  
Vol 61 (Suppl 2) ◽  
pp. A119.1-A119
Author(s):  
C R Grant ◽  
R Liberal ◽  
B Holder ◽  
Y Ma ◽  
G Mieli-Vergani ◽  
...  
Keyword(s):  
T Cell ◽  
Regulatory T Cell ◽  
Sclerosing Cholangitis ◽  
Autoimmune Sclerosing Cholangitis

scholarly journals Regulatory T‐cell conditioning endows activated effector T cells with suppressor function in autoimmune hepatitis/autoimmune sclerosing cholangitis

Hepatology ◽  
2017 ◽  
Vol 66 (5) ◽  
pp. 1570-1584 ◽  
Author(s):  
Rodrigo Liberal ◽  
Charlotte R. Grant ◽  
Muhammed Yuksel ◽  
Jonathon Graham ◽  
Alireza Kalbasi ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Autoimmune Hepatitis ◽  
Regulatory T Cell ◽  
Sclerosing Cholangitis ◽  
Effector T Cells ◽  
Suppressor Function ◽  
Autoimmune Sclerosing Cholangitis

scholarly journals Interleukin 2 Promotes Hepatic Regulatory T Cell Responses and Protects From Biliary Fibrosis in Murine Sclerosing Cholangitis

Hepatology ◽  
2018 ◽  
Vol 68 (5) ◽  
pp. 1905-1921 ◽  
Author(s):  
Amy E. Taylor ◽  
Alexandra N. Carey ◽  
Ramesh Kudira ◽  
Celine S. Lages ◽  
Tiffany Shi ◽  
...  
Keyword(s):  
T Cell ◽  
Regulatory T Cell ◽  
Sclerosing Cholangitis ◽  
Interleukin 2 ◽  
T Cell Responses ◽  
Cell Responses

scholarly journals In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression

Hepatology ◽  
2015 ◽  
Vol 62 (3) ◽  
pp. 863-875 ◽  
Author(s):  
Rodrigo Liberal ◽  
Charlotte R. Grant ◽  
Beth S. Holder ◽  
John Cardone ◽  
Marc Martinez-Llordella ◽  
...  
Keyword(s):  
T Cell ◽  
Autoimmune Hepatitis ◽  
Regulatory T Cell ◽  
Sclerosing Cholangitis ◽  
Autoimmune Hepatitis Type 1
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