Short-term and long-term outcome of early invasive therapy in patients with non-ST-segment elevation acute coronary syndrome: a meta-analysis

Aim: Identification of predictors of unfavorable annual prognosis in patients with acute coronary syndrome with ST-segment elevation (STEMI). Material and methods: The study included 69 patients with STEMI who were hospitalized in the period from March 2014 to January 2017 in the hospital named after Zhadkevich. The follow-up period was 12±3 months after the index STEMI Longterm prognosis was established in 62 (89.8%) patients. Results: the fatal outcome was observed in 7 (11.3%) patients. Nonfatal myocardial infarction developed in 10 (16.2%), hospitalization with heart failure decompensation - in 5 (8%), nonfatal acute cerebrovascular accident - in 3 (4.8%) patients. Predictors of adverse prognosis were: age >60 years, level of brain natriuretic peptide (BNP) >29.2 pmol/l, C-reactive protein (CRP) >4.7 mg/l, left ventricular ejection fraction (LVF) 60 years and BNP level >29.2 pmol/l. Conclusion: Adverse factors affecting the long-term outcome of the disease (12±3 months after the STEMI) are: BNP level >29.2 pmol/l, CRP level >4.7 mg/l, LV FV value 60 years.

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Plasma Catestatin in Patients with Acute Coronary Syndrome

Cardiology ◽

10.1159/000448987 ◽

2016 ◽

Vol 136 (3) ◽

pp. 164-169 ◽

Cited By ~ 5

Author(s):

Weixian Xu ◽

Haiyi Yu ◽

Hubing Wu ◽

Siheng Li ◽

Baoxia Chen ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Coronary Syndrome ◽

Major Adverse Cardiovascular Events ◽

Control Group ◽

Term Outcome ◽

Long Term Outcome ◽

St Segment Elevation ◽

Coronary Syndrome ◽

St Segment ◽

Artery Disease

Objectives: To measure plasma catestatin levels in patients with acute coronary syndrome and investigate whether there is an association between catestatin levels and long-term outcome. Methods: Patients (n = 170) with suspected acute coronary syndrome who underwent emergency coronary angiography were enrolled, including 46 with acute ST-segment elevation myocardial infarction (STEMI), 89 with unstable angina pectoris (UAP), and 35 without coronary artery disease (CAD). All patients were followed for 2 years to measure the occurrence of major adverse cardiovascular events (MACEs), including death from a cardiovascular cause, recurrent acute myocardial infarction, or hospital admission for heart failure or revascularization. Results: On average, the plasma catestatin levels in patients with STEMI (0.80 ± 0.62 ng/ml) and UAP (0.99 ± 0.63 ng/ml) were significantly lower than the levels seen in the control group with no evidence of CAD (1.38 ± 0.98 ng/ml; p = 0.001). In multivariable linear regression, body mass index, presence of hypertension, and type of CAD were independently related to the plasma catestatin level. However, there were no significant differences in MACEs between patients with high and low levels of catestatin. Conclusions: The plasma catestatin levels in patients with STEMI and UAP were lower than the levels seen in patients without CAD.

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IMPACT OF PRE-OPERATIVE CLOPIDOGREL USE IN PATIENTS WITH NON-ST SEGMENT ELEVATION ACUTE CORONARY SYNDROME REQUIRING CORONARY ARTERY BYPASS GRAFTING: A META-ANALYSIS

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(10)61728-7 ◽

2010 ◽

Vol 55 (10) ◽

pp. A185.E1727

Author(s):

Rohit Bhuriya ◽

Pawan Patel ◽

Dhara Chaudhari ◽

Amol Bahekar ◽

Ankur Sethi ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Coronary Artery ◽

Coronary Artery Bypass Grafting ◽

Coronary Artery Bypass ◽

Meta Analysis ◽

Artery Bypass ◽

Bypass Grafting ◽

St Segment Elevation ◽

Coronary Syndrome ◽

St Segment

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Clinical Characteristics, Short- and Long-term Outcome of Acute Coronary Syndrome in Young Adults

The American Journal of Cardiology ◽

10.1016/j.amjcard.2013.01.202 ◽

2013 ◽

Vol 111 (7) ◽

pp. 80B

Author(s):

Keiji Yamada ◽

Satoru Sakuragi ◽

Kota Okabe ◽

Takashi Fuziwara ◽

Takashi Miki ◽

...

Keyword(s):

Acute Coronary Syndrome ◽

Young Adults ◽

Clinical Characteristics ◽

Term Outcome ◽

Long Term Outcome ◽

Coronary Syndrome ◽

Short And Long Term

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Kidney Dysfunction and Long-Term Outcome in Post-PCI Acute Coronary Syndrome Patients Treated by High-Dose Tirofiban: The Role of Creatinine Clearance

British Journal of Medicine and Medical Research ◽

10.9734/bjmmr/2013/2764 ◽

2013 ◽

Vol 3 (4) ◽

pp. 897-913 ◽

Cited By ~ 2

Author(s):

Paolo Puddu

Keyword(s):

Acute Coronary Syndrome ◽

Creatinine Clearance ◽

High Dose ◽

Kidney Dysfunction ◽

Term Outcome ◽

Long Term Outcome ◽

Coronary Syndrome

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Association of Soluble Suppression of Tumorigenicity with No-Reflow Phenomenon and Long-Term Prognosis in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome after Percutaneous Coronary Intervention

Journal of Atherosclerosis and Thrombosis ◽

10.5551/jat.59832 ◽

2021 ◽

Author(s):

Qinyao Zhang ◽

Meirong Hu ◽

Shumei Ma

Keyword(s):

Percutaneous Coronary Intervention ◽

Acute Coronary Syndrome ◽

Coronary Intervention ◽

St Segment Elevation ◽

Coronary Syndrome ◽

St Segment ◽

Percutaneous Coronary ◽

No Reflow Phenomenon ◽

Long Term Prognosis

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Early coronary angiography and percutaneous coronary intervention for out of hospital cardiac arrest survivors without ST-segment elevation: a systematic review and meta-analysis

10.21203/rs.3.rs-51274/v1 ◽

2020 ◽

Author(s):

Po Huang ◽

Qingquan Liu ◽

Yuhong Guo ◽

Bo Li ◽

Xiaolei Fang

Keyword(s):

Meta Analysis ◽

Coronary Intervention ◽

Controlled Study ◽

Short Term ◽

St Segment Elevation ◽

Randomized Controlled ◽

St Segment ◽

Percutaneous Coronary ◽

Hospital Cardiac Arrest

Abstract Objective: The meta-analysis aims to identify whether out of hospital cardiac arrest (OHCA) survivors of non ST-segment elevation (NSTE) can benefit from early coronary angiography (CAG) and percutaneous coronary intervention (PCI).Methods: The relevant studies from MEDLINE, Cochrane Library, Embase were searched by two independent investigators using a variety of keywords. Stata software (version 12.0, Stata Corp LP, College Station, TX, USA) was used for statistical analysis. Results: A total of 12 studies (9 observational studies, 1 cohort study and 2 randomized control trials) were identified and incorporated into the meta-analysis. For overall analysis, the strategy of early angiography was associated with decreased short-term (hospital discharged) mortality (RR=0.72, 95% CI=0.56-0.93, P=0.000) and long-term (follow up) mortality (RR=0.84, 95% CI=0.71-0.99, P=0.007). However, when analyzed in the subgroup of randomized controlled study, the strategy of early angiography didn’t have survival benefit in the randomized controlled study group for short-term mortality (RR=1.12, 95% CI=0.89-1.41, P=0.331) and long-term mortality (RR=1.06, 95% CI=0.85-1.32, P=0.572). Meanwhile, our analysis found that, if early CAG performed, PCI followed by CAG is not associated with hospital discharged mortality (RR=1.14, 95% CI=0.96-1.37, P=0.132) compared with CAG alone. No significant differences between the groups were found in the remaining secondary endpoints.Conclusion: Due to the observational nature of the studies available, we may consider that early CAG and PCI is not be recommended for patients with NSTE OHCA.

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