EP1337 A primary extended cytoreductive surgery for ovarian cancer: total abdominal hysterectomy and bilateral salpingo-oophorectomy, total omentectomy, total peritonectomy, bilateral diaphragm stripping, cholecystectomy, total colectomy, splenectomy, bilateral pelvic-paraaortic lymphadenectomy, dissection of porta hepatis, liver metastasectomy, and bilateral cardiophrenic lymphadenectomy

Author(s):  
C Taskiran ◽  
D Vatansever ◽  
A Eraslan ◽  
B Giray ◽  
S Misirlioglu ◽  
...  
2021 ◽  
Vol 8 (8) ◽  
pp. 2454
Author(s):  
Abhirup H. R. ◽  
Priyanka Kenchetty ◽  
Aishwarya K. Chidananda

BRCA1 and BRCA2, known as breast and ovarian cancer predisposition genes, were discovered in the 1990s. As part of a normal genetic structure, these genes are intrinsic to all human beings, but they are mutated in some individuals increasing the risk for breast and ovarian cancers development. BRCA1 is not only expressed in endocrine tissues but is also detected in other cells such as the neuroepithelial cells in the early stage of cell development. Like BRCA1, BRCA2 is also expressed in a wide variety of tissues and is observed with higher rates in the breast and thymus and with lower rates in the lung, ovary and spleen. We presented to you a case of 40 year old female admitted in surgical ward with lump in the left breast since 2 months with ipsilateral discrete axillary lymphadenopathy. Bilateral sono-mammography showed BIRADS V lesion in left breasts with satellite nodules. Ultrasonography of abdomen and pelvis showed large left adnexal solid mass lesion and right sided ovarian cyst with retrocaval, preaortic lymphadenopathy. Patient underwent a diagnostic laparoscopy which was converted to a laparotomy. Total abdominal hysterectomy with bilateral salphingo-oophorectomy was done. For the breast lump, patient underwent left sided modified radical mastectomy. Gene testing for revealed BRCA1 positivity. Chemotherapy was given to cover both breast and ovarian carcinoma. Patient came back with abdominal distension after 9 months and was offered palliative care. Patient succumbed for disease after 1 year after diagnosis. We reviewed the literature for the same.


Author(s):  
G. A. Ebughe ◽  
T. I. Ugbem ◽  
E. E. Omoronyia

Female genital tuberculosis is one the known causes of infertility in the tropics. The symptom complex are diverse and it is one of the known causes of pyrexia of unknown origin. Instances of mimicry of ovarian cancer with raised CA125, have been reported. We present a case report in a 42-year-old woman with abdominal pain and progressive abdominal pain of 3 weeks durations, who had confounding symptom of raised CA125, forcing a presumptive diagnosis of ovarian cancer. She had exploratory total abdominal hysterectomy (TAH). The surgical findings and histopathological diagnosis were suggestive of tuberculosis, for which she is undergoing treatment and showing remarkable improvement.


2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 412-414
Author(s):  
J. Abu ◽  
L. Brown ◽  
D. Ireland ◽  
E. Sizeland

We present the case of a 48-year-old woman with pelvic mass, ascites, and an elevated CA125 mimicking advanced-stage ovarian cancer. She underwent laparotomy, drainage of ascites, total abdominal hysterectomy, bilateral salpingo-oophorectomy, and infracolic omentectomy. Histology confirmed this to be mesovarian hemangioma, a benign condition.


Author(s):  
Saad Ahmed Naved ◽  
Sadiq Shoukat Parpia ◽  
Huma Shoukat Ali

Abstract: Pseudomyxoma Peritonei, a massive mucinous peritoneal collection due to a rare epithelial neoplasm, can be effectively treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC). 43-year-old female, previously treated for mucinous ovarian carcinoma with CRS-HIPEC, Total Abdominal Hysterectomy and Bilateral Salpingo-Oophorectomy, presented with new-onset abdominal distension and early satiety. She was diagnosed with Pseudomyxoma Peritonei. After 48 hours of treatment with CRS-HIPEC, she presented hemodynamically unstable with acute chest pain. Electrocardiogram showed broad complex tachycardia with ST depression in leads V3-6. Severe systolic dysfunction with EF of 20% along with severe pulmonary hypertension was visualized on Echocardiography. A diagnosis of Stress-induced Cardiomyopathy was established using InterTAK Diagnostic Score. Patients with CRS-HIPEC have presented with Stress-induced Cardiomyopathy. However, no relation between the two has been established, specifically. Thus, this case report discusses Stress-induced Cardiomyopathy as a complication of CRS-HIPEC. Continuous...


2021 ◽  
Vol 29 (1) ◽  
pp. 83-88
Author(s):  
Adhir Kumar Das

Approximately 80% ovarian tumorsare benign, and these arise mostly in young adult females. Malignant tumors are more prevalent in ageing women, between the ages of 45-65 years. Mucinous ovarian cancer represents about 5% of epithelial ovarian cancers (EOC).We have reported a case of mucinous cystadenocarcinoma in 35-year-old lady with metastasis to omentum.Imaging (radiograph & CT scan) studies showed a large right sided pelvic mass with probable origin in the right ovary. Cancer antigen-125 was elevated, while carcinoembrionic antigen and alphafetoprotein were normal. Mutational profiles shown distinct finding, as KRAS mutations positive nevertheless p53 and BRCA mutations are absent. She had undergone total abdominal hysterectomy with bilateral salphingo-oopherectomy along with pelvic dissection for removal of lymph nodes at the age of 35. She was given advice for radiotherapy with 3 cycles of chemotherapy with cisplatin and paclitaxel. To the best of our knowledge, this is the one of the littlecase of ovarian mucinous cystadenocarcinoma being reported at a relatively young age, and the first case being reported from Bangladesh. J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 83-88


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