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917 Phase 1b trial of first-line bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, plus chemotherapy with or without bevacizumab in cervical cancer
Mapping Intimacies
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10.1136/ijgc-2021-esgo.75
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2021
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Author(s):
A Oaknin
◽
M Gil-Martin
◽
E Diver
◽
G Jehl
◽
SA Gleicher
◽
...
Keyword(s):
Cervical Cancer
◽
Fusion Protein
◽
Protein Targeting
◽
First Line
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Phase 1B
◽
Bifunctional Fusion Protein
Download Full-text
Related Documents
Cited By
References
776P SHR-1701, a bifunctional fusion protein targeting PD-L1 and TGF-β, for pretreated advanced cervical cancer: Data from a clinical expansion cohort of a phase I study
Annals of Oncology
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10.1016/j.annonc.2021.08.1218
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2021
◽
Vol 32
◽
pp. S753
Author(s):
J. Feng
◽
J. Wang
◽
D. Tang
◽
Q. Zhou
◽
J. Peng
◽
...
Keyword(s):
Cervical Cancer
◽
Fusion Protein
◽
Phase I
◽
Phase I Study
◽
Protein Targeting
◽
Advanced Cervical Cancer
◽
Cancer Data
◽
Bifunctional Fusion Protein
◽
Expansion Cohort
Download Full-text
1278P SHR-1701, a bifunctional fusion protein targeting PD-L1 and TGF-β, as first-line therapy for PD-L1+ advanced/metastatic NSCLC: Data from a clinical expansion cohort of a phase I study
Annals of Oncology
◽
10.1016/j.annonc.2021.08.1880
◽
2021
◽
Vol 32
◽
pp. S995
Author(s):
J. Feng
◽
J. Chen
◽
K. Li
◽
X. Li
◽
X. Min
◽
...
Keyword(s):
Fusion Protein
◽
Phase I
◽
Phase I Study
◽
Protein Targeting
◽
First Line
◽
Metastatic Nsclc
◽
First Line Therapy
◽
Line Therapy
◽
Bifunctional Fusion Protein
◽
Expansion Cohort
Download Full-text
116 Evaluation of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in cervical cancer: data from phase 1 and phase 2 studies
10.1136/ijgc-2021-esgo.8
◽
2021
◽
Author(s):
J Strauss
◽
F Braiteh
◽
E Calvo Aller
◽
M De Miguel
◽
A Cervantes
◽
...
Keyword(s):
Cervical Cancer
◽
Fusion Protein
◽
Protein Targeting
◽
Phase 1
◽
Phase 2
◽
Cancer Data
◽
Bifunctional Fusion Protein
Download Full-text
P37 Phase 1 evaluation of bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1, in cervical cancer
10.1136/ijgc-2019-esgo.100
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2019
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Author(s):
S Allan
◽
F Braiteh
◽
E Calvo Aller
◽
A Cervantes
◽
W Edenfield
◽
...
Keyword(s):
Cervical Cancer
◽
Fusion Protein
◽
Protein Targeting
◽
Phase 1
◽
Bifunctional Fusion Protein
Download Full-text
879TiP Phase II study of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in platinum-experienced advanced cervical cancer
Annals of Oncology
◽
10.1016/j.annonc.2020.08.1018
◽
2020
◽
Vol 31
◽
pp. S644-S645
Author(s):
M.J. Birrer
◽
L.R. Mileshkin
◽
K. Fujiwara
◽
I. Ray-Coquard
◽
J. Alexandre
◽
...
Keyword(s):
Cervical Cancer
◽
Fusion Protein
◽
Phase Ii
◽
Protein Targeting
◽
Phase Ii Study
◽
Advanced Cervical Cancer
◽
Bifunctional Fusion Protein
Download Full-text
Abstract CT075: Phase I evaluation of M7824, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus (HPV)-associated malignancies
10.1158/1538-7445.sabcs18-ct075
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2019
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Author(s):
Julius Strauss
◽
Margaret E. Gatti-Mays
◽
Byoung Cho
◽
Sébastien Salas
◽
Edward McClay
◽
...
Keyword(s):
Human Papillomavirus
◽
Fusion Protein
◽
Phase I
◽
Protein Targeting
◽
Bifunctional Fusion Protein
Download Full-text
Updated results from a phase I trial of M7824 (MSB0011359C), a bifunctional fusion protein targeting PD-L1 and TGF-β, in patients with pretreated recurrent or refractory gastric cancer
Annals of Oncology
◽
10.1093/annonc/mdy282.045
◽
2018
◽
Vol 29
◽
pp. viii222-viii223
◽
Cited By ~ 5
Author(s):
Y.-J. Bang
◽
T. Doi
◽
S. Kondo
◽
H.C. Chung
◽
K. Muro
◽
...
Keyword(s):
Gastric Cancer
◽
Fusion Protein
◽
Phase I
◽
Phase I Trial
◽
Protein Targeting
◽
Bifunctional Fusion Protein
Download Full-text
Results from a second-line (2L) NSCLC cohort treated with M7824 (MSB0011359C), a bifunctional fusion protein targeting TGF-β and PD-L1.
Journal of Clinical Oncology
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10.1200/jco.2018.36.15_suppl.9017
◽
2018
◽
Vol 36
(15_suppl)
◽
pp. 9017-9017
◽
Cited By ~ 6
Author(s):
Luis G. Paz-Ares
◽
Tae Min Kim
◽
David Vicente Baz
◽
Enriqueta Felip
◽
Dae Ho Lee
◽
...
Keyword(s):
Fusion Protein
◽
Protein Targeting
◽
Second Line
◽
Bifunctional Fusion Protein
Download Full-text
Selection of the recommended phase 2 dose (RP2D) for M7824 (MSB0011359C), a bifunctional fusion protein targeting TGF-β and PD-L1.
Journal of Clinical Oncology
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10.1200/jco.2018.36.15_suppl.2566
◽
2018
◽
Vol 36
(15_suppl)
◽
pp. 2566-2566
◽
Cited By ~ 4
Author(s):
Yulia Vugmeyster
◽
Justin Wilkins
◽
Eleanor Harrison-Moench
◽
Wanping Geng
◽
Andre Koenig
◽
...
Keyword(s):
Fusion Protein
◽
Protein Targeting
◽
Phase 2
◽
Bifunctional Fusion Protein
◽
Selection Of
Download Full-text
957O Long-term follow-up of patients (pts) with human papillomavirus (HPV)–associated malignancies treated with bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1
Annals of Oncology
◽
10.1016/j.annonc.2021.08.1342
◽
2021
◽
Vol 32
◽
pp. S829
Author(s):
J. Strauss
◽
M. Gatti-Mays
◽
B.C. Cho
◽
A. Hill
◽
S. Salas
◽
...
Keyword(s):
Human Papillomavirus
◽
Fusion Protein
◽
Protein Targeting
◽
Long Term Follow Up
◽
Bifunctional Fusion Protein
Download Full-text
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