scholarly journals EPV079/#495 Accuracy of magnetic resonance imaging for preoperative prediction of pathologic tumor size and the need of adjuvant radiotherapy in early-stage cervical cancer

2021 ◽  
Author(s):  
D Kim ◽  
U Kim ◽  
SJ Park ◽  
M Lee ◽  
HS Kim ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Cancer ◽  
Magnetic Resonance ◽  
Tumor Size ◽  
Adjuvant Radiotherapy ◽  
Early Stage ◽  
Resonance Imaging ◽  
Preoperative Prediction ◽  
Early Stage Cervical Cancer

The Role of Magnetic Resonance Imaging in Pretreatment Evaluation of Early-Stage Cervical Cancer

2014 ◽  
Vol 24 (7) ◽  
pp. 1292-1298 ◽  
Author(s):  
Wei Zhang ◽  
Jie Zhang ◽  
Jiaxin Yang ◽  
Huadan Xue ◽  
Dongyan Cao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Cancer ◽  
Lymph Node ◽  
Magnetic Resonance ◽  
Tumor Size ◽  
Early Stage ◽  
Pelvic Examination ◽  
Resonance Imaging ◽  
Parametrial Invasion ◽  
Early Stage Cervical Cancer

ObjectiveThe aim of this study is to evaluate the accuracy of magnetic resonance imaging (MRI) in the preoperative assessments of primary tumor size, parametrial invasion, and pelvic lymph node metastasis in patients with early-stage cervical cancer.Materials and MethodsA cohort of 125 patients with International Federation of Gynecology and Obstetrics stage IA2 to IIA cervical cancer who had preoperative MRI and underwent radical hysterectomy were enrolled and analyzed. The accuracy of preoperative MRI scan and pelvic examination in the measurement of tumor size was assessed based on postoperative measurement and pathologic findings. The accuracy of detection of lymph node status and parametrial invasion was also assessed by comparing the MRI and pathologic findings.ResultsThe mean diameter of the tumor size measured by postoperative measurement, MRI, and pelvic examination was 2.97 ± 1.39 cm, 2.78 ± 1.24 cm, and 1.97 ± 1.70 cm, respectively. There were significant differences in the mean diameter of the tumor size between pelvic examinations and MRI scan or postoperative measurement (P < 0.0001). Based on postoperative measurement findings, accuracy of tumor size measurement between pelvic examination and MRI was determined by the degree of agreement with a difference of less than 0.5 or 1.0 cm. Pelvic examination and MRI had an accuracy of 24.75% and 39.60%, respectively, with a difference of less than 0.5 cm, and had an accuracy of 43.56% and 61.39%, respectively, with a difference of less than 1.0 cm. Correlation with postoperative measurement in tumor size was higher for MRI (r[s] = 0.481) than that for pelvic examination (r[s] = 0.362). The sensitivity, specificity, and accuracy of MRI in detecting lymph node metastasis were 27.78%, 85.98%, 77.60%, respectively. The negative predictive value of MRI in detecting parametrial invasion is 100%.ConclusionsMagnetic resonance imaging is an accurate noninvasive modality for preoperative evaluation of tumor size and also gives important information to parametrial invasion and lymph node status in patients with early-stage cervical cancer.

Early-stage cervical cancer: Tumor delineation by magnetic resonance imaging and ultrasound — A European multicenter trial

2013 ◽  
Vol 128 (3) ◽  
pp. 449-453 ◽  
Author(s):  
Elisabeth Epstein ◽  
Antonia Testa ◽  
Adrius Gaurilcikas ◽  
Alessia Di Legge ◽  
Liveke Ameye ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Cancer ◽  
Magnetic Resonance ◽  
Early Stage ◽  
Multicenter Trial ◽  
Resonance Imaging ◽  
Tumor Delineation ◽  
Early Stage Cervical Cancer ◽  
Cancer Tumor

Early stage cervical cancer: role of magnetic resonance imaging after conization in determining residual tumor

2016 ◽  
Vol 57 (10) ◽  
pp. 1268-1276 ◽  
Author(s):  
Sungmin Woo ◽  
Hye Sung Kim ◽  
Hyun Hoon Chung ◽  
Sang Youn Kim ◽  
Seung Hyup Kim ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Cancer ◽  
Magnetic Resonance ◽  
Early Stage ◽  
Residual Tumor ◽  
Resonance Imaging ◽  
Early Stage Cervical Cancer

scholarly journals A prospective study of the value of pre- and post-treatment magnetic resonance imaging examinations for advanced cervical cancer

2016 ◽  
Vol 89 (3) ◽  
pp. 410-418
Author(s):  
Csaba Csutak ◽  
Claudia Ordeanu ◽  
Viorica Magdalena Nagy ◽  
Diana Cristina Pop ◽  
Sorana Daniela Bolboaca ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Cancer ◽  
Magnetic Resonance ◽  
Prospective Study ◽  
Tumor Size ◽  
Post Treatment ◽  
Disease Stage ◽  
Resonance Imaging ◽  
A Prospective Study ◽  
Post Therapy

Background and aim. Cervical cancer has high incidence and mortality in developing countries. It is the only gynecological malignancy that is clinically staged. Staging at the time of diagnosis is crucial for treatment planning. After radiation therapy, clinical examination is limited because of radiation changes. An imaging method relatively unaffected by radiation changes would be useful for the assessment of therapy results and for management.We sought to demonstrate the value of magnetic resonance imaging (MRI) in the pre- and post-treatment assessment of cervical cancer.Methods. This was a prospective study, carried out between November 2012 and October 2014 on 18 subjects with advanced-stage cervical cancer diagnosed by colposcopy. The disease stage was determined clinically according to the International Federation of Gynecology and Obstetrics (FIGO) criteria. Only patients with disease stage ≥ IIB or IIA with one of the tumor dimensions > 4 cm were enrolled in the study. All patients underwent abdominal-pelvic contrast-enhanced MRI as part of the workup. Tumor size, local invasion, involved pelvic lymph nodes, and staging according to MRI criteria were evaluated. Clinical and MRI examinations were also performed after chemoradiotherapy. After chemoradiotherapy, 94% of the patients (17 of 18) were treated surgically.Results. Eighteen patients aged 32–67 met the inclusion criteria and were enrolled: 10 stage IIB, 6 stage IIIA, 1 stage IIA and 1 stage IIIB, according to clinical staging. Using histopathological findings as a reference, MRI staging accuracy was 83.3%. The concordance of the clinical stage with MRI stage at the first examination was 56%. Parametrial involvement was assessed on pretreatment and post-treatment MRI, with post-treatment MRI compared with histology. There was no statistically significant difference between the pre- and post-therapy gynecological examinations (GYN) and the corresponding MRI assessments as to tumor size measurements (p>0.05). The post-therapy restoration of the cervical stroma ruled out tumor recurrence.Conclusions. For a detailed characterization of loco-regional extension, the calculation of tumor volume, and the evaluation of distant  metastatic changes, clinical examination is insufficient. Magnetic resonance imaging is helpful aftertherapy.

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