Influences on human papillomavirus (HPV)-related information needs among women having HPV tests for follow-up of abnormal cervical cytology

Abstract Background: High-risk human papillomavirus (HR-HPV) infection is widely known as the major cause of cervical intraepithelial neoplasia (CIN) and cervical cancer and it’s characteristics vary greatly in different population. Women with abnormal cervical cytology could increase the risk of cervical cancer, however, HR-HPV infection characteristics in women with abnormal cervical cytology remains unclear. Methods: This study was based on baseline survey of the CIN Cohort established in Shanxi Province, China. A total number of 2300 women with cervical abnormalities were enrolled in this study. All participants gave informed consent and agreed to HPV and thinprepcytologic test (TCT). Each individual completed a questionnaire about characteristics related to HPV infection. Results: The overall prevalence of HR-HPV in 2300 women was 32.0%, and the proportion of single and multiple HR-HPV infections were 70.2% and 29.8% in HR-HPV infection women, respectively. The top five HR-HPV genotypes were ranked as HPV16, HPV58, HPV52, HPV53 and HPV51. The prevalence of HR-HPV in atypical squamous cells of undetermined significance (ASC-US), low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion and above(HSIL+) were 30.8%, 36.5% and 54.9%, respectively, showing an increasing trend with the severity of cervical cytology ( χ 2 trend =13.952; p <0.001). The women aged 35~45 years, with lower education level, less frequency of bathing, multiple gravidity, multiple parity, history of gynecological diseases and premenopausal women were prone to HR-HPV infection. Conclusions: We defined the characteristics related to HR-HPV infection in abnormal cervical cytology women, and provided an insight for the development and deeply research of HPV vaccine.

Download Full-text

Relationships of Sexually Transmitted Infections, Bacterial (STI) with High-Risk Human Papillomavirus (HR-HPV) and Abnormal Cervical Cytology in Gynecological Outpatients

Journal of the American Society of Cytopathology ◽

10.1016/j.jasc.2015.09.080 ◽

2015 ◽

Vol 4 (6) ◽

pp. S34

Author(s):

Sung Ran Hong ◽

Tae Jin Kim ◽

In Ho Lee ◽

Hye Sun Kim

Keyword(s):

Human Papillomavirus ◽

High Risk ◽

Sexually Transmitted Infections ◽

Cervical Cytology ◽

Sexually Transmitted ◽

Abnormal Cervical Cytology

Download Full-text

Providing high quality information about human papillomavirus for women after treatment for high-grade cervical dysplasia

Sexual Health ◽

10.1071/sh09059 ◽

2010 ◽

Vol 7 (1) ◽

pp. 49 ◽

Cited By ~ 4

Author(s):

Suzanne Dyson ◽

Marian Pitts ◽

Anthony Lyons ◽

Robyn Mullins

Keyword(s):

Human Papillomavirus ◽

Information Needs ◽

Qualitative Interviews ◽

Cervical Dysplasia ◽

Pap Test ◽

Intraepithelial Neoplasia ◽

General Information ◽

High Grade ◽

Hpv Testing

Background: The present study aimed to inform the production of a resource for women who have had a high-grade cervical abnormality and are scheduled to undergo testing for human papillomavirus (HPV) at their 12-month follow-up. Methods: Two rounds of semi-structured, qualitative interviews were held with women who were attending a gynaecological oncology clinic at a major teaching hospital for women in Melbourne, Australia, 6 months after treatment for cervical intraepithelial neoplasia (CIN) to receive a follow-up Pap test and colposcopy. In an initial round of interviews, we gauged the reactions of 16 women to an existing information brochure containing general information about HPV. Based on the findings from the interviews, a second brochure aimed specifically for women scheduled to undergo HPV testing as part of their post treatment follow-up was drafted. Feedback was then gathered from a further 12 women. Results: While all participants had received some information and counselling about HPV and HPV testing as part of their treatment, many still experienced high levels of stress and anxiety about cancer and the sexually transmissible nature of HPV. Many also still had unanswered questions about HPV, their treatment regime and future prognosis. Conclusion: For a brochure to provide an effective adjunct to counselling, it is essential that it is carefully developed and pilot tested to ensure that it is easily understood and meets the information needs of the target audience. Such materials need to provide both medical and psychosocial information about HPV and be presented in accessible, easy to understand language.

Download Full-text