scholarly journals 296 Case series involving obstetrics experiences and outcomes in connective tissue disease patient in universiti kebangsaan malaysia medical centre (ukmmc): a single centre experience

2017 ◽  
Author(s):  
MS Mohamed Said ◽  
JB Eeu ◽  
AS Mohamed Yazid ◽  
A Chandra ◽  
FN Ahmad Yazid ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Disease Patient ◽  
Case Series ◽  
Medical Centre ◽  
Single Centre ◽  
Single Centre Experience

scholarly journals Replacing a phosphodiesterase-5 inhibitor with riociguat in patients with connective tissue disease-associated pulmonary arterial hypertension: a case series

2017 ◽  
Vol 7 (3) ◽  
pp. 741-746 ◽  
Author(s):  
Amresh Raina ◽  
Raymond L. Benza ◽  
Harrison W. Farber
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Connective Tissue ◽  
Arterial Hypertension ◽  
Clinical Response ◽  
Connective Tissue Disease ◽  
Case Series ◽  
Response To Treatment ◽  
Tolerability Profile ◽  
Phosphodiesterase Type 5 Inhibitors ◽  
Pulmonary Arterial

Patients with pulmonary arterial hypertension associated with connective tissue disease (PAH-PAH-CTD) such as systemic sclerosis (SSc) have a poorer response to treatment and increased mortality compared with patients with idiopathic PAH. Current treatment options for PAH-CTD include prostanoids, phosphodiesterase type-5 inhibitors (PDE-5i), endothelin receptor antagonists, and the soluble guanylate cyclase stimulator riociguat. In this case series, we describe three patients with PAH-CTD related to limited scleroderma who were switched from a PDE-5i to riociguat due to insufficient clinical response. The switch to riociguat was associated with an improvement in respiratory and hemodynamic parameters and a favorable tolerability profile. These cases demonstrate that switching to riociguat is a therapeutic option in patients with PAH-CTD who have not achieved a satisfactory clinical response to a PDE-5i.

scholarly journals Case Series Of Silvery Hair Syndrome - A Single Centre Experience

2018 ◽  
Vol 3 (3) ◽  
pp. S16
Author(s):  
B. Varshini ◽  
S. Sirisha Rani ◽  
V. Sandhya ◽  
kumar Soma Santosh
Keyword(s):  
Case Series ◽  
Single Centre ◽  
Single Centre Experience
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