scholarly journals Increased cyclin D1 expression in cancer of the ampulla of Vater: relevance to nuclear   catenin accumulation and k-ras gene mutation

2003 ◽  
Vol 56 (6) ◽  
pp. 336-341 ◽  
Author(s):  
K Yamazaki
Keyword(s):  
Cyclin D1 ◽  
Gene Mutation ◽  
Ampulla Of Vater ◽  
Ras Gene

Relationship between cyclooxygenase-2 expression and K-ras gene mutation in colorectal adenomas

2000 ◽  
Vol 15 (11) ◽  
pp. 1277-1281
Author(s):  
Mikio Fujita ◽  
Hirokazu Fukui ◽  
Katsuo Morita ◽  
Shigehiko Fujii ◽  
Yoshihiko Ueda ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Cyclooxygenase 2 ◽  
Colorectal Adenomas ◽  
Ras Gene

Inverse Association Between Cyclin D1 Overexpression and Retinoblastoma Gene Mutation in Thyroid Carcinomas

Endocrine ◽  
1998 ◽  
Vol 8 (1) ◽  
pp. 61-64 ◽  
Author(s):  
Minjing Zou ◽  
Yufei Shi ◽  
Nadir R. Farid ◽  
Sultan T. Al-Sedairy
Keyword(s):  
Cyclin D1 ◽  
Gene Mutation ◽  
Inverse Association ◽  
Retinoblastoma Gene ◽  
Thyroid Carcinomas

K-ras gene mutation as an early prognostic marker of colon cancer

2016 ◽  
Vol 88 (1) ◽  
Author(s):  
Łukasz Szpon ◽  
Aleksander Stal ◽  
Marcin Zawadzki ◽  
Anna Lis-Nawara ◽  
Wojciech Kielan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Gene Mutation ◽  
Cancer Incidence ◽  
Early Stage ◽  
Tnm Classification ◽  
Gene Mutations ◽  
Diagnostic Methods ◽  
Female Group ◽  
Ras Gene ◽  
Colorectal Cancer Incidence

AbstractDue to increased colorectal cancer incidence there is a necessity of seeking new both prognostic and prediction factors that will allow to evolve new diagnostic tests. K-ras gene seems to be such a factor and its mutations are considered to be an early marker of progression of colorectal cancer.was to find a correlation between K-ras gene mutation in patients with diagnosed colorectal cancer and selected clinical parameters.A total of 104 patients (41 women and 63 men) with diagnosed colorectal cancer were included in this study. The average age of male group was 68.3 and in female group − 65.9. Samples were taken from paraffine blocks with tissue from diagnosed patients and K-ras gene mutation were identified. Afterwards the statistical analysis was made seeking the correlation between K-ras gene mutation incidence and clinical TNM staging system, tumour localisation, histological type, sex, age.K-ras gene mutations were detected in 20.1% of all colorectal cancers. Significantly higher rate of K-ras gene mutations were diagnosed among patients classified at stage I (40%), stage IIC (50%) and stage IV (50%) according to the TNM classification.The results of our study are compatible with other studies and indicate the correlation between K-ras gene mutation and colorectal cancer incidence. Identification of K-ras gene mutation may complement other diagnostic methods at early stage of colorectal cancer.

Gastric-type endocervical glandular neoplasms associated with aberrant p16 expression and K-RAS gene mutation in Peutz-Jeghers syndrome

2014 ◽  
Vol 64 (6) ◽  
pp. 283-288 ◽  
Author(s):  
Shigemi Ito ◽  
Toru Tase ◽  
Kennichi Satoh ◽  
Miyuki Ueki ◽  
Ikuro Sato ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Ras Gene ◽  
Gastric Type ◽  
Peutz Jeghers Syndrome ◽  
P16 Expression

Characteristic association between K- ras gene mutation with loss of heterozygosity in X-ray-induced thymic lymphomas of the B6C3F1 mouse

2001 ◽  
Vol 77 (4) ◽  
pp. 465-473 ◽  
Author(s):  
Y. Shimada ◽  
M. Nishimura ◽  
S. Kakinuma ◽  
T. Takeuchi ◽  
T. Ogiu ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Loss Of Heterozygosity ◽  
Ras Gene ◽  
X Ray ◽  
B6c3f1 Mouse

Cyclooxygenase-2 Overexpression Is Related to Polypoid Growth and K-ras Gene Mutation in T1 Colorectal Carcinomas

2004 ◽  
Vol 47 (11) ◽  
pp. 1915-1921 ◽  
Author(s):  
Takuya Okawa ◽  
Keigo Yoshinaga ◽  
Hiroyuki Uetake ◽  
Takanobu Sato ◽  
Tetsuro Higuchi ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Cyclooxygenase 2 ◽  
Colorectal Carcinomas ◽  
Ras Gene ◽  
Polypoid Growth

K-ras gene mutation in non-small cell lung cancer in Japanese

Lung Cancer ◽  
2000 ◽  
Vol 29 (1) ◽  
pp. 207
Author(s):  
N Noda ◽  
D Matsuzoe ◽  
T Konno ◽  
K Kawahara ◽  
Y Yamashita ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Gene Mutation ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Ras Gene
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