Accuracy of optical coherence tomography imaging in assessing aneurysmal remnants after flow diversion

2020 ◽  
pp. neurintsurg-2020-016129 ◽  
Author(s):  
Frederik Fries ◽  
Alexander Maßmann ◽  
Toshiki Tomori ◽  
Umut Yilmaz ◽  
Michael Kettner ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Flow Diverter ◽  
Diagnostic Tools ◽  
Imaging Method ◽  
Optical Coherence ◽  
Conventional Angiography ◽  
Device Implantation ◽  
Optical Coherence Tomography Imaging ◽  
Stent Lumen

BackgroundOptical coherence tomography (OCT) is an ultra-high resolution real-time intravascular imaging method that is gaining interest in cerebrovascular applications.ObjectiveTo compare, in a rabbit elastase aneurysm model, digital subtraction angiography (DSA) and OCT as diagnostic tools for the assessment of aneurysmal remnants and baseline characteristics of aneurysms after flow diverter (FD) implantation.MethodsWith Institutional Animal Care and Use Committee approval, saccular aneurysms were created in 28 rabbits and treated with Derivo FDs. DSA was performed before, and immediately after, stent implantation. As a follow-up, DSA and OCT were performed 28 days after device implantation.ResultsDSA and OCT were successfully performed in 23 cases. OCT could not be achieved in 5 cases owing to navigational difficulties in the stent lumen with the OCT catheter. Residual aneurysms were significantly more often visible with OCT (18/23 (78%) than with DSA 12/23 (52%), p = 0.031).ConclusionOCT was more sensitive than conventional angiography for the assessment of residual aneurysms at 28 days after FD implantation in an animal model.

Recurrent Spontaneous Macular Hole Formation and Resolution in a Patient With Previous Vitrectomy

2020 ◽  
pp. 247412642096534
Author(s):  
Nathalie Massamba ◽  
Eric K. Chin ◽  
David R.P. Almeida
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Hole ◽  
Spontaneous Closure ◽  
Optical Coherence ◽  
Vitreoretinal Interface ◽  
Tomography Imaging ◽  
History Of ◽  
Optical Coherence Tomography Imaging ◽  
Macular Hole Formation

Purpose: We report a case of recurrent macular hole (MH) formation and spontaneous closure in the absence of any vitreoretinal interface abnormality. Methods: A 49-year-old man presented for his annual ocular examination with no specific ocular complaints. He had a history of retinal detachment in the left eye, which was treated years prior with vitrectomy and scleral buckle. During a routine follow-up, the patient was discovered to have a full-thickness MH. Optical coherence tomography revealed the formation of an MH with spontaneous closure after 3 months without intervention. One month later, the MH recurred but once again closed spontaneously over 4 months. Results: The patient remained asymptomatic during the entire follow-up without any symptoms, vision changes, or therapeutic intervention. Conclusions: To our knowledge, this is the first known case report of recurrent spontaneous opening and closure of an MH in the absence of any vitreoretinal interface abnormality, as revealed by macular optical coherence tomography imaging.

scholarly journals Whole Eye Optical Coherence Tomography Imaging

2018 ◽  
Vol 1 (2) ◽  
Keyword(s):  
Optical Coherence Tomography ◽  
Imaging Method ◽  
High Resolution Imaging ◽  
Optical Coherence ◽  
Pathological Changes ◽  
Tomography Imaging ◽  
Ocular Accommodation ◽  
Resolution Imaging ◽  
Optical Coherence Tomography Imaging ◽  
Parameters Measurement

Many eye diseases will affect the shape and dimensions of the whole eye. For examination of ocular accommodation and pathological changes caused by these diseases, high resolution imaging of the whole eye segments OCT system is needed. However, limited by the imaging depth, traditional Fourier Domain Optical Coherence Tomography (FDOCT) can’t be used for real time whole eye segment imaging. In recent years, techniques for depth extended FD-OCT system especially for whole eye segment imaging has been developed. Application on eye parameters measurement and eye accommodation studies were successfully performed. In this paper, both of whole eye FD-OCT techniques and their application were reviewed. Potential clinical application of these techniques may be in the detection of the pathological changes of the whole eye, and whole eye segment FD-OCT system also provides a powerful imaging method for ophthalmic research, such as accommodation, ocular growth, and biometry of the eye.

scholarly journals En Face Optical Coherence Tomography Imaging Ellipsoid Zone Regeneration in Laser-Induced and Solar Maculopathies

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Jeanne M. Gunzinger ◽  
Katrin Fasler ◽  
Daniel Barthelmes ◽  
Peter Maloca ◽  
Pascal W. Hasler ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Optical Coherence ◽  
Retrospective Case ◽  
Ellipsoid Zone ◽  
En Face Oct ◽  
En Face ◽  
Optical Coherence Tomography Imaging ◽  
Sd Oct

The purpose of the study was to analyze imaging findings in spectral domain en face optical coherence tomography (SD OCT) in patients with laser‐induced and solar maculopathies focusing on the possible regeneration of the ellipsoid zone. In a retrospective case series of 3 patients (4 eyes) with solar maculopathy and 2 patients (3 eyes) with laser‐induced maculopathy who underwent a comprehensive ocular examination, ellipsoid zone (EZ) was segmented from SD OCT data. Evaluation of EZ in en face OCT revealed a hyporeflective lesion surrounded by a hyperreflective border. The area of EZ alteration was measured manually in en face OCT. All patients showed partial EZ regeneration. Mean EZ alteration decreased from 0.12 mm2 (range: 0.05–0.32) at baseline to 0.07 mm2 (range: 0.01–0.22) at last follow‐up (p=0.018, mean follow‐up: 372 days; range: 115–592). Mean best visual acuity (BVA) improved from 20/36 at baseline to 20/30 (p=0.018). In conclusion, en face OCT imaging clearly delineated the area of EZ alteration in patients with laser‐induced and solar maculopathies. Follow-up showed significant reformation of the EZ as well as improvement of BVA.

Optical Coherence Tomography

2017 ◽  
pp. 58-68
Keyword(s):  
Optical Coherence Tomography ◽  
Differential Diagnosis ◽  
Imaging Techniques ◽  
Imaging Method ◽  
Retinal Diseases ◽  
Optical Coherence ◽  
Tomography Imaging ◽  
Retinal Layers ◽  
Quantitative Analyses ◽  
Optical Coherence Tomography Imaging

Optical coherence tomography is a very useful imaging method in the diagnosis of retinal diseases. This modality provides knowledge to the underlying retinal layers and helps to quantitative analyses of retinal layers that yield very useful information. Recently, optical coherence tomography has become the most important tool of diagnosis, following, and differential diagnosis of retinal diseases. This review mentions the optical coherence tomography imaging techniques.

Communicating malapposition of flow diverters assessed with optical coherence tomography correlates with delayed aneurysm occlusion

2017 ◽  
Vol 10 (7) ◽  
pp. 693-697 ◽  
Author(s):  
Robert M King ◽  
Olivia W Brooks ◽  
Erin T Langan ◽  
Jildaz Caroff ◽  
Frédéric Clarençon ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Positive Outcome ◽  
Flow Diverter ◽  
Fisher Exact Test ◽  
Imaging Method ◽  
Optical Coherence ◽  
Exact Test ◽  
Treatment Groups ◽  
Potential Factor ◽  
Flow Diverters

BackgroundOptical coherence tomography (OCT) is a high resolution intravascular imaging method that allows visualization of flow diverter struts and the vessel wall. In this study, malapposition of the flow diverter that continues into the neck of the aneurysm, named communicating malapposition (CM), was investigated as a potential factor for delayed aneurysm healing.Methods40 New Zealand White rabbits underwent elastase induced aneurysm creation, and were subsequently assigned to one of four treatment groups based on flow diverter type and administration of antiplatelet therapy. All animals underwent post device deployment balloon angioplasty and subsequent OCT to assess device/vessel apposition. The incidence of CM seen on OCT was assessed with a binary scoring system: 0–CM present; 1–CM absent. At 30 days, DSA was acquired to assess aneurysm healing. Aneurysm healing on terminal DSA was measured using a previously developed 5 point scale, with a score of 3 or 4 considered a positive outcome.ResultsAll animals were grouped into a single cohort for analysis as no difference in the rate of CM or healing was seen in the four treatment groups. Significant interaction between the absence of CM and a positive outcome was confirmed by Fisher exact test (P=0.0034). Angioplasty was shown to treat 33% of the cases of CM seen at implant, and these treated cases overwhelmingly had a positive outcome (P<0.001).ConclusionThe use of OCT to assess CM of flow diverters has been shown to be predictive of the 30 day healing rate of an animal model of aneurysms.

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