scholarly journals P57 Patient global impression of severity scale characterises symptom severity in chronic cough

Author(s):  
K Rhatigan ◽  
K Tsami ◽  
H Kesavan ◽  
RD Turner ◽  
CJ Jolley ◽  
...  
2012 ◽  
Author(s):  
Merlene Miller ◽  
Amanda L. C. Chen ◽  
Stan D. Stokes ◽  
Susan Silverman ◽  
Abdalla Bowirrat ◽  
...  

2019 ◽  
Vol 109 (4) ◽  
pp. 343-350
Author(s):  
J. Multanen ◽  
J. Ylinen ◽  
T. Karjalainen ◽  
H. Kautiainen ◽  
J. P. Repo ◽  
...  

Background and Aims: The Boston Carpal Tunnel Questionnaire is the most commonly used outcome measure in the assessment of carpal tunnel syndrome. The purpose of this study was to translate the original Boston Carpal Tunnel Questionnaire into Finnish and validate its psychometric properties. Materials and Methods: We translated and culturally adapted the Boston Carpal Tunnel Questionnaire into Finnish. Subsequently, 193 patients completed the Finnish version of the Boston Carpal Tunnel Questionnaire, 6-Item CTS Symptoms Scale, and EuroQol 5 Dimensions 12 months after carpal tunnel release. The Boston Carpal Tunnel Questionnaire was re-administered after a 2-week interval. We calculated construct validity, internal consistency, test–retest reliability, and coefficient of repeatability. We also examined floor and ceiling effects. Results: The cross-cultural adaptation required only minor modifications to the questions. Both subscales of the Boston Carpal Tunnel Questionnaire (Symptom Severity Scale and Functional Status Scale) correlated significantly with the CTS-6 and EuroQol 5 Dimensions, indicating good construct validity. The Cronbach’s alpha was 0.93 for both the Symptom Severity Scale and Functional Status Scale, indicating high internal consistency. Test–retest reliability was excellent, with an intraclass correlation coefficient greater than 0.8 for both scales. The coefficient of repeatability was 0.80 for the Symptom Severity Scale and 0.68 for the Functional Status Scale. We observed a floor effect in the Functional Status Scale in 28% of participants. Conclusion: Our study shows that the present Finnish version of the Boston Carpal Tunnel Questionnaire is reliable and valid for the evaluation of symptom severity and functional status among surgically treated carpal tunnel syndrome patients. However, owing to the floor effect, the Functional Status Score may have limited ability to detect differences in patients with good post-operative outcomes.


2010 ◽  
Vol 18 (4) ◽  
pp. 333-346 ◽  
Author(s):  
Katherine A. Henderson ◽  
Annick Buchholz ◽  
Julie Perkins ◽  
Sarah Norwood ◽  
Nicole Obeid ◽  
...  

2019 ◽  
Vol 3 (1) ◽  
pp. 137-147 ◽  
Author(s):  
Joanne Dudeney ◽  
Emily F. Law ◽  
Alagumeena Meyyappan ◽  
Tonya M. Palermo ◽  
Jennifer A. Rabbitts

2021 ◽  
Vol 10 (7) ◽  
pp. e15010715225
Author(s):  
Stheace Kelly Fernandes Szezerbaty ◽  
Carlos Alexandre Martins Zicarelli ◽  
Luana Oliveira de Lima ◽  
Priscila Daniele Oliveira Perrucini ◽  
Karen Barros Parron Fernandes ◽  
...  

To investigate the influence of the catechol-O-methyltransferase enzyme (COMT) single nucleotide polymorphism (SNP) rs4680 (G/A) on fibromyalgia in women. In this observational study of case-control type 29 women with a diagnosis of FM (cases) and 31 healthy non-fibromyalgia women (controls). Sociodemographic and anthropometric data were collected, as well as data relating to Symptom Severity Scale and Generalized Pain Index and peripheral blood samples for DNA extraction; genotypic analyzes were performed by PCR-SSP. We observed that rs4680 AA genotype was more frequently observed in fibromyalgia than controls (p=0.02). The A allele was also more often present in the fibromyalgia participants than in their control peers (p = 0.03). There was a statistically significant association between race and FM sufferers, showing that those of white ethnicity had a 2.05 times greater chance of developing the syndrome than non-white individuals (p=0.03; CI 95% 0.93 – 4.53). A statistically significant correlation between age and FM was observed (rS=0.812, p=0.01). This study demonstrates that white women above the age of 45, who have the AA genotype or A-allele, presents a higher risk of developing FM, showing that this polymorphism of the COMT gene may be one of the risk factors for the fibromyalgia.


Neurology ◽  
2018 ◽  
Vol 90 (19) ◽  
pp. e1711-e1719 ◽  
Author(s):  
Joseph F. McGuire ◽  
John Piacentini ◽  
Eric A. Storch ◽  
Tanya K. Murphy ◽  
Emily J. Ricketts ◽  
...  

ObjectiveTo examine the internal consistency and distribution of the Yale Global Tic Severity Scale (YGTSS) scores to inform modification of the measure.MethodsThis cross-sectional study included 617 participants with a tic disorder (516 children and 101 adults), who completed an age-appropriate diagnostic interview and the YGTSS to evaluate tic symptom severity. The distributions of scores on YGTSS dimensions were evaluated for normality and skewness. For dimensions that were skewed across motor and phonic tics, a modified Delphi consensus process was used to revise selected anchor points.ResultsChildren and adults had similar clinical characteristics, including tic symptom severity. All participants were examined together. Strong internal consistency was identified for the YGTSS Motor Tic score (α = 0.80), YGTSS Phonic Tic score (α = 0.87), and YGTSS Total Tic score (α = 0.82). The YGTSS Total Tic and Impairment scores exhibited relatively normal distributions. Several subscales and individual item scales departed from a normal distribution. Higher scores were more often used on the Motor Tic Number, Frequency, and Intensity dimensions and the Phonic Tic Frequency dimension. By contrast, lower scores were more often used on Motor Tic Complexity and Interference, and Phonic Tic Number, Intensity, Complexity, and Interference.ConclusionsThe YGTSS exhibits good internal consistency across children and adults. The parallel findings across Motor and Phonic Frequency, Complexity, and Interference dimensions prompted minor revisions to the anchor point description to promote use of the full range of scores in each dimension. Specific minor revisions to the YGTSS Phonic Tic Symptom Checklist were also proposed.


2018 ◽  
Author(s):  
RP Lovegrove ◽  
PSP Cho ◽  
HV Fletcher ◽  
RD Turner ◽  
SS Birring

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1570-1570
Author(s):  
A. Ayan ◽  
H. Hekim ◽  
S. Y. Cetin

Background:As with other connective tissue diseases, fibromyalgia (FMS) syndrome is not uncommon in scleroderma. However, there is no clear information about it in the literature. According to 1990 ACR criteria, sensitive point evaluation was made in scleroderma and FMS frequency was reported as 18.6% in scleroderma patients. However, it is known that fibrosis creates difficulties in sensitive point determination. moreover, ACR 1990 criteria cannot be met in approximately 25% of fibromyalgia patients. Therefore, the frequency of fibromyalgia in scleroderma patients is unclear. In 1990, ACR announced new criteria in 2010 due to the low sensitivity of ACR criteria to FMS detection and not being used in the follow-up of the disease. In the new set of criteria, not the 18 sensitive point evaluations, but the Widespread Pain Index and Symptom Severity Scale are evaluated.Objectives:In this study, we planned to investigate the frequency of fibromyalgia in systemic sclerosis patients according to the new ACR criteria defined in 2010.Methods:43 patients with diffuse systemic sclerosis with no known additional diseases were included in the study. Patients were evaluated with the new fibromyalgia diagnostic criteria set. Patients were evaluated with Fibromyalgia Impact Questionnaire (FIQ), Pain Location Score (PLS), Symptom Impact Questionnaire (SEA), Widespread Pain Index (WPI) and Symptom Severity Scale (SSS).Results:The mean age of the patients was 53.45 ± 12.87 years (39 women, 4 men). Mean values were FIQ: 46.05 ± 17.44, PLS:18.32 ± 9.87, SEA: 20.76 ± 11.31, WPI: 7.93 ± 5.87, SSS: 6.51 ± 3.41 respectively. According to these results, 62.8% (n: 27) FMS presence of SS patients was detected.Conclusion:In the literature, there are only a few studies evaluating the frequency of FMS in scleroderma patients. Malcarne et al. reported that 18.6% of 102 SSc patients met the 1990 classification criteria for FMS. However, there are predominantly early-stage systemic sclerosis patients in this study and the patient group is heterogeneous. We included patients with diffuse systemic sclerosis and widespread skin involvement in this study. we found a much higher frequency of fibromyalgia syndrome than indicated in the literature. Considering that systemic sclerosis is a serious disease that significantly impairs quality of life, this finding is very important. In order to relieve the symptoms associated with FMS, it is important to provide them with additional medical support, to provide as much exercise as possible, and to provide group therapies to improve patients’ quality of life.References:[1]Management of Musculoskeletal Involvement in Systemic Sclerosis. Philip Clements. Curr Treatm Opt Rheumatol. 2016 Mar; 2(1): 61–68.[2]Malcarne VL, Hansdottir I, McKinney A, Upchurch R, Greenbergs HL, Henstorf GH, Furst DE, Clements PJ, Weisman MH. Medical signs and symptoms associated with disability, pain, and psychosocial adjustment in systemic sclerosis. J Rheumatol. 2007;34:359–367.Disclosure of Interests:None declared


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