Description of the outbreak of equine influenza (H3N8) in the United Kingdom in 2003, during which recently vaccinated horses in Newmarket developed respiratory disease

2006 ◽  
Vol 158 (6) ◽  
pp. 185-192 ◽  
Author(s):  
J. R. Newton ◽  
J. M. Daly ◽  
L. Spencer ◽  
J. A. Mumford
2017 ◽  
Vol 30 (1) ◽  
pp. 126-129
Author(s):  
Ann P. Britton ◽  
Shlomo E. Blum ◽  
Carolyn Legge ◽  
Ken Sojonky ◽  
Erin N. Zabek

Streptococcus equi subspecies zooepidemicus ( S. zooepidemicus) causes outbreaks of fatal respiratory disease in dog shelters and fatal respiratory and neurologic disease in cat shelters. We conducted multi-locus sequence typing analysis on S. zooepidemicus isolates from 5 Canadian and 3 Israeli cats with severe respiratory and neurologic disease, plus 1 isolate from a clinically normal shelter cat. Our aim was to determine if feline outbreaks are clonal and whether there is commonality between feline and canine strains. ST363 was identified as the causative strain of a Canadian outbreak of S. zooepidemicus–linked disease, and is a double-locus variant of ST173, which was isolated from one of the Israeli cats. ST363 was also isolated from the clinically normal cat, indicative of the potential for enzootic infection in shelters. Strains within the ST173 clonal complex were responsible for 2 large canine outbreaks in the United States and the United Kingdom, as well as the death of 1 cat in the United States outbreak. ST215 was isolated from 2 cats in the Israeli outbreak, and is unrelated to the ST173 complex. We conclude that S. zooepidemicus outbreaks in cat shelters are clonal and that strains within the ST173 clonal complex are pathogenic for both dogs and cats.


1993 ◽  
Vol 133 (21) ◽  
pp. 515-519 ◽  
Author(s):  
G. Livesay ◽  
T. O'Neill ◽  
D. Hannant ◽  
M. Yadav ◽  
J. Mumford

1999 ◽  
Vol 145 (16) ◽  
pp. 449-452 ◽  
Author(s):  
J. R. Newton ◽  
K. Verheyen ◽  
J. L. N. Wood ◽  
P. J. Yates ◽  
J. A. Mumford

2005 ◽  
Vol 156 (12) ◽  
pp. 367-371 ◽  
Author(s):  
C. Edlund Toulemonde ◽  
J. Daly ◽  
T. Sindle ◽  
P. M. Guigal ◽  
J. C. Audonnet ◽  
...  

Pathogens ◽  
2017 ◽  
Vol 6 (1) ◽  
pp. 6 ◽  
Author(s):  
Adam Rash ◽  
Rachel Morton ◽  
Alana Woodward ◽  
Olivia Maes ◽  
John McCauley ◽  
...  

BMJ ◽  
2018 ◽  
pp. k4680 ◽  
Author(s):  
Justin D Salciccioli ◽  
Dominic C Marshall ◽  
Joseph Shalhoub ◽  
Mahiben Maruthappu ◽  
Giuseppe De Carlo ◽  
...  

AbstractObjectiveTo compare age standardised death rates for respiratory disease mortality between the United Kingdom and other countries with similar health system performance.DesignObservational study.SettingWorld Health Organization Mortality Database, 1985-2015.ParticipantsResidents of the UK, Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, the Netherlands, Portugal, Spain, Sweden, Australia, Canada, the United States, and Norway (also known as EU15+ countries).Main outcome measuresMortality from all respiratory disease and infectious, neoplastic, interstitial, obstructive, and other respiratory disease. Differences between countries were tested over time by mixed effect regression models, and trends in subcategories of respiratory related diseases assessed by a locally weighted scatter plot smoother.ResultsBetween 1985 and 2015, overall mortality from respiratory disease in the UK and EU15+ countries decreased for men and remained static for women. In the UK, the age standardised death rate (deaths per 100 000 people) for respiratory disease mortality in the UK fell from 151 to 89 for men and changed from 67 to 68 for women. In EU15+ countries, the corresponding changes were from 108 to 69 for men and from 35 to 37 in women. The UK had higher mortality than most EU15+ countries for obstructive, interstitial, and infectious subcategories of respiratory disease in both men and women.ConclusionMortality from overall respiratory disease was higher in the UK than in EU15+ countries between 1985 and 2015. Mortality was reduced in men, but remained the same in women. Mortality from obstructive, interstitial, and infectious respiratory disease was higher in the UK than in EU15+ countries.


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