IDENTIFICATION AND NOMENCLATURE FOR G-BANDED BOVINE CHROMOSOMES

1977 ◽  
Vol 19 (2) ◽  
pp. 271-282 ◽  
Author(s):  
C. C. Lin ◽  
D. R. Newton ◽  
R. B. Church
Keyword(s):  
Chromosome Aberrations ◽  
Bovine Chromosome ◽  
Banding Technique ◽  
Human Chromosomes ◽  
Giemsa Banding ◽  
Unequivocal Identification

A reliable trypsin-Giemsa banding technique for producing clearly differentiated G-bands on bovine chromosomes was introduced. Unequivocal identification of individual bovine chromosome pairs is now possible. A system similar to the standardization of human chromosomes was proposed for the nomenclature of the G-bands. This scheme of nomenclature will facilitate the identification and recording of chromosome aberrations in this species.

Relevance of chromosome 13 aberrations in canine tumours

2012 ◽  
Vol 40 (04) ◽  
pp. 267-270 ◽  
Author(s):  
H. Escobar ◽  
I. Nolte ◽  
N. Reimann-Berg
Keyword(s):  
Chromosome Aberrations ◽  
Human Chromosomes ◽  
High Homology ◽  
Chromosome 13 ◽  
Human Tumours ◽  
Cytogenetic Studies ◽  
Canine Chromosome ◽  
Chromosomal Changes

SummaryFor human tumours there are many reports documenting the correlation between chromosome aberrations and tumour entities. Due to the complex canine karyotypic pattern (78 chromosomes), cytogenetic studies of tumours of the dog are rare. However, the reports in the literature show, that canine chromosome 13 (CFA 13) is predominantly involved in chromosomal changes. Interestingly, CFA 13 shows high homology to regions on the human chromosomes 4 (HSA 4) and 8 (HSA 8), which harbour the proto-oncogenes c-KIT and c-MYC. Both of these genes are involved in the development and progression of some human and canine tumour diseases.

scholarly journals Double Aneuploidy - A Rare Condition : Report of Two Cases

2015 ◽  
Vol 32 (3) ◽  
pp. 171-173
Author(s):  
Saequa Habib ◽  
Sultana Gulshana Banu ◽  
SM Shahedul Islam ◽  
Choudhury Ali Kawser
Keyword(s):  
Peripheral Blood ◽  
Cytogenetic Analysis ◽  
Trisomy 21 ◽  
Rare Condition ◽  
Chromosome Abnormalities ◽  
Banding Technique ◽  
Giemsa Banding ◽  
Rare Disorders ◽  
Phenotypic Features ◽  
Double Aneuploidy

The chance of two chromosome abnormalities occurring in one conceptus is rare. Here we report two cases of double aneuploidy with karyotype 48,XYY,+21 and 48,XXY,+21.The diagnosis was confirmed by cytogenetic analysis using peripheral blood followed by Giemsa banding technique. Clinically both the children had most of the phenotypic features of Trisomy 21. However phenotypic features of XYY were not present but the child with XXY had undescended right testis .The purpose of this communication is to report such rare disorders discovered as the result of the evaluation for Trisomy 21.J Bangladesh Coll Phys Surg 2014; 32: 171-173

Visualization of interphase chromosomes

1977 ◽  
Vol 26 (1) ◽  
pp. 281-299
Author(s):  
S.M. Stack ◽  
D.B. Brown ◽  
W.C. Dewey
Keyword(s):  
Allium Cepa ◽  
Chinese Hamster ◽  
Banding Technique ◽  
Giemsa Banding ◽  
Root Tips ◽  
Chinese Hamster Cells ◽  
3 Dimensional ◽  
Structural Modifications

Using a modified Giemsa-banding technique we have observed what appear to be chromosomes during interphase in nuclei from Allium cepa root tips and Chinese hamster cells (CHO line). During telophase through G1 chromosomes progressively uncoil and decondense. During S chromosomes are comparatively decondensed, but some segments have structure similar to chromosomes in G1 and G2. During G2 the chromosomes progressively recondense and coil in apparent preparation for prophase. Although specific structural modifications of chromosomes occur in G1, Sand G2 nuclei, chromosomes appear never to decondense to the point that they lose their 3-dimensional integrity, but remain in distinct domains throughout interphase.

scholarly journals Charles Edmund Ford. 24 October 1912 – 7 January 1999

2001 ◽  
Vol 47 ◽  
pp. 189-201 ◽  
Author(s):  
Mary F. Lyon
Keyword(s):  
Chromosome Aberrations ◽  
Scientific Method ◽  
Mammalian Cells ◽  
Human Chromosomes ◽  
Cell Lineages ◽  
Human Cytogenetics ◽  
Equal Importance ◽  
Mammalian Genetics ◽  
The 1960S ◽  
Haemopoietic Cells

Charles Edmund Ford was distinguished for his outstanding contributions to mammalian cytogenetics, particularly human cytogenetics. He was especially renowned for his part in establishing the number of human chromosomes as 46, rather than 48 as previously believed. However, his contributions to the use of chromosome variants as cell markers in tracing cell lineages, particularly of haemopoietic cells, were of equal importance. He had a great mastery of cytological techniques and his ability to devise suitable methods for mammalian cells was a major factor in his contribution to the explosive advance of human and other mammalian genetics in the 1960s. Equally important were his superb observational powers in interpreting chromosome aberrations under the microscope, and his scrupulous adherence to scientific method.

scholarly journals Chromosomal Abnormalities in Endometrial and Ovarian Carcinomas

2007 ◽  
Vol 10 (2) ◽  
pp. 61-70 ◽  
Author(s):  
A Pazarbaşi ◽  
M Kasap ◽  
O Demirhan ◽  
M Vardar ◽  
D Suleymanova-Karahan ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Chromosomal Abnormalities ◽  
Banding Technique ◽  
Giemsa Banding ◽  
Specific Chromosome ◽  
Ovarian Carcinomas ◽  
Genetic Changes ◽  
Cytogenetic Studies ◽  
Chromosomal Instabilities ◽  
Chromosome Bands

Chromosomal Abnormalities in Endometrial and Ovarian CarcinomasDevelopment and progression of human malignancies involve multiple genetic changes including chromosomal instabilities such as translocations, deletions, and inversions. Chromosomal abnormalities were observed in 23 cases with ovarian and endometrial cancer by cytogenetic studies using a GTG (G bands by trypsin using Giemsa) banding technique. Specific chromosome bands were frequently involved, and were most frequent on chromosomes 1, 2, 3, 5, 12 and 17. Clonal alterations were observed at the cancer breakpoints, such as 1q21, 1q32, 3p21, 7q22, 11q23 in ovarian and 1p36, 1q32, 2p12, 3p21, 7q22, 9q34, 11p15, 11q23, 12q13, 14q11, 14q32, 16p13, 21q22 in endometrial cases. These findings provide evidence that multiple genetic lesions are associated with the pathogenesis of endometrial and ovarian cancer.

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