MICROPROBE ANALYSIS IN BIOLOGICAL SAMPLES

During the last few years, the nuclear microprobe has demonstrated itself as a strong research facility in the application to biological samples. The performance is not without competition from new techniques, and to maintain special advantages of the nuclear microprobe, care must be taken in the selection and preparation of the biological samples to analyse.

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Nuclear microprobe analysis of 14N and its application to the study of ammonium-bearing minerals

Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms ◽

10.1016/0168-583x(93)95579-t ◽

1993 ◽

Vol 77 (1-4) ◽

pp. 450-456 ◽

Cited By ~ 14

Author(s):

M. Mosbah ◽

A. Bastoul ◽

M. Cuney ◽

J. Pironon

Keyword(s):

Microprobe Analysis ◽

Nuclear Microprobe

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Applications of nuclear microprobe analysis to dermatological research

Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms ◽

10.1016/s0168-583x(97)00238-3 ◽

1997 ◽

Vol 130 (1-4) ◽

pp. 454-459 ◽

Cited By ~ 3

Author(s):

Jan Pallon ◽

Bo Forslind ◽

Ylva Werner-Linde ◽

C. Yang ◽

R.J. Utui ◽

...

Keyword(s):

Microprobe Analysis ◽

Nuclear Microprobe

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Occupational Contamination with Cyclophosphamide in Manipulators

European Journal of Public Health ◽

10.1093/eurpub/ckaa040.044 ◽

2020 ◽

Vol 30 (Supplement_2) ◽

Author(s):

S Martins ◽

Z Moreira

Keyword(s):

Health Professionals ◽

Biological Samples ◽

Urine Samples ◽

Detection Methods ◽

Technological Innovations ◽

Inclusion Criteria ◽

New Techniques ◽

Main Route ◽

Scientific Papers

Abstract Introduction Cyclophosphamide is a cytotoxic widely used in the treatment of various cancers. It has been observed, for many years, that those responsible for its handling and administration are exposed and levels of contamination have been detected in biological samples collected from these professionals, in surfaces and in the air. Objectives To review the literature on occupational contamination by cyclophosphamide. Methodology The following inclusion criteria were selected: articles published until the present year, articles in English, scientific papers on cyclophosphamide contamination in hospital health professionals, scientific articles on contamination detection methods and articles on the effects that can outcome from cyclophosphamide contamination. Results The cyclophosphamide levels have been decreasing with the implementation of preparation and cleaning guidelines as well as with the emergence of new techniques of manipulation and technological innovations. However, the dermal route remains the main route of contamination and those responsible for cytotoxic manipulation are not the only ones exposed. It was verified that hospital professionals, who in their profession would not be in contact with cyclophosphamide, also presented levels of contamination in the collected urine samples. Conclusion It is necessary to continue to alert hospital professionals to the importance of always complying with the handling and cleaning protocols, since one of the main causes of contamination is precisely the performance of incorrect procedures during both tasks. This is a topic that should be further studied in order to minimize the exposure and consequently the associated risks.

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