Superoxide Anion Scavenging Effect of Coumarins
1996 ◽
Vol 24
(01)
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pp. 11-17
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Keyword(s):
The superoxide scavenging effects of fifteen coumarins were tested on the xanthine-xanthine oxidase-cytochrome C system. The results showed that fraxetin(10) displayed the strongest activity, and its percent inhibition at 100, 10 and 1 μM were 100, 100 and 53.13% respectively. Esculetin(4) showed the second strongest activity resulting in percent inhibition at 100 and 10 μM were 87.16 and 52.38% respectively. Both fraxetin(10) and esculetin(4) have been isolated from the plant, Fraxinus bungeana DC (Oleaceae) which has been used in folk medicine as an analgesic and anti-inflammatory medicine. It seems that two phenolic hydroxy groups in the ortho position in the molecule of coumarins play an important role in scavenging activity.
2016 ◽
Vol 67
(3)
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pp. 283-287
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2013 ◽
Vol 781-784
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pp. 1138-1143
1997 ◽
Vol 233
(2)
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pp. 447-450
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2000 ◽
Vol 80
(5)
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pp. 601-606
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Keyword(s):
2011 ◽
Vol 183-185
◽
pp. 145-150
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1981 ◽
Vol 45
(03)
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pp. 290-293
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Keyword(s):
2019 ◽
Vol 9
(3)
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pp. 238-243
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1962 ◽
Vol 237
(2)
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pp. 584-586
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2016 ◽
Vol 94
(1)
◽
pp. 44-49
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