Development of heavy-ion radiotherapy technology with HIMAC

2016 ◽  
Vol 44 ◽  
pp. 1660219 ◽  
Author(s):  
Koji Noda

Since 1994, HIMAC has carried out clinical studies and treatments for more than 9000 cancer patients with carbon-ion beams. During the first decade of the HIMAC study, a single beam-wobbling method, adopted as the HIMAC beam-delivery technique, was improved for treatments of moving tumors and for obtaining more conformal dose distribution. During the second decade, a pencil-beam 3D scanning method has been developed toward an “adaptive cancer treatment” for treatments of both static and moving tumors. A new treatment research facility was constructed with HIMAC in order to verify the developed 3D scanning technology through a clinical study that has been successfully conducted since 2011. As the next stage, a compact heavy-ion rotating gantry with a superconducting technology has been developed for the more accurate and shorter-course treatments. The twenty-year development of the heavy-ion radiotherapy technologies including accelerator technologies with HIMAC is reviewed.

2009 ◽  
Vol 36 (6Part16) ◽  
pp. 2639-2639
Author(s):  
F Bourhaleb ◽  
A Attili ◽  
G Russo ◽  
E Schmitt ◽  
R Cirio ◽  
...  

2017 ◽  
Vol 41 (9) ◽  
pp. 098201 ◽  
Author(s):  
Yuan-Lin Yan ◽  
Xin-Guo Liu ◽  
Zhong-Ying Dai ◽  
Yuan-Yuan Ma ◽  
Peng-Bo He ◽  
...  

1989 ◽  
Vol 50 (C1) ◽  
pp. C1-629-C1-641
Author(s):  
Y. JONGEN

2020 ◽  
Vol 15 (12) ◽  
pp. T12015-T12015
Author(s):  
L.J. Mao ◽  
J.C. Yang ◽  
W.Q. Yang ◽  
J.W. Xia ◽  
Y.J. Yuan ◽  
...  
Keyword(s):  

2010 ◽  
Vol 37 (11) ◽  
pp. 5672-5682 ◽  
Author(s):  
Takuji Furukawa ◽  
Taku Inaniwa ◽  
Shinji Sato ◽  
Toshiyuki Shirai ◽  
Yuka Takei ◽  
...  

1983 ◽  
Vol 30 (4) ◽  
pp. 2077-2079 ◽  
Author(s):  
R. S. Lord ◽  
J. B. Ball ◽  
E. D. Hudson ◽  
P. K. Kloeppel ◽  
C. A. Ludemann ◽  
...  
Keyword(s):  

2021 ◽  
Vol 11 ◽  
Author(s):  
Yuanchang Jin ◽  
Jingwen Li ◽  
Jieyun Li ◽  
Na Zhang ◽  
Kangle Guo ◽  
...  

BackgroundHeavy ion radiotherapy (HIRT) has great advantages as tumor radiotherapy.MethodsBased on 1,558 literatures from core collections of Web of Science from 1980 to 2020, this study visually analyzes the evolution of HIRT research, and sorts out the hotspots and trends of HIRT research using CiteSpace software.ResultsResearch on HIRT has received more extensive attention over the last 40 years. The development of HIRT is not only closely related to radiation and oncology, but also closely related to the development of human society. In terms of citation frequency, “International Journal of Radiation Oncology*Biology*Physics” was the top journal. In terms of influence, “Radiotherapy and Oncology” was the top journal. “Radiation therapy” and “carbon ion radiotherapy” were the two most frequently used keywords in this field.ConclusionThe evolution of the HIRT research has occurred in approximately three stages, including technological exploration, safety and effectiveness research and technological breakthroughs. Finally, some suggestions for future research are put forward.


2018 ◽  
Author(s):  
Simon Edward Blackwell ◽  
Marcella Woud ◽  
Jürgen Margraf ◽  
Felix D. Schönbrodt

The application of basic science research to the development and optimization of psychological treatments holds great potential. However, this process of clinical translation is challenging and time-consuming, and the standard route by which it proceeds is inefficient. Adaptive rolling designs, which originated within cancer treatment research, provide an alternative methodology with potential to accelerate development and optimization of psychological treatments. In such designs, multiple treatment options are tested simultaneously, with sequential Bayesian analyses used to remove poorly performing arms. Further, new treatment arms informed by the latest research findings can be introduced into the existing infrastructure as the trial progresses. These features drastically reduce the sample sizes needed and offer a means for more rapid and efficient clinical translation. This paper outlines the utility of such designs to clinical psychological science, focusing on a new variant termed the ‘leapfrog’ design, and discusses their potential uses to accelerate clinical translation.


Measurement ◽  
2015 ◽  
Vol 67 ◽  
pp. 61-70 ◽  
Author(s):  
Agnes Psikuta ◽  
Joanna Frackiewicz-Kaczmarek ◽  
Emel Mert ◽  
Marie-Ange Bueno ◽  
Renè M. Rossi
Keyword(s):  
Air Gap ◽  

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