PROS2E, a Probabilistic Representation of Safety and Security Events for Diagnosis

Author(s):  
Edwin Bourget ◽  
Frédéric Cuppens ◽  
Nora Cuppens-Boulahia
1987 ◽  
Vol 26 (03) ◽  
pp. 117-123
Author(s):  
P. Tautu ◽  
G. Wagner

SummaryA continuous parameter, stationary Gaussian process is introduced as a first approach to the probabilistic representation of the phenotype inheritance process. With some specific assumptions about the components of the covariance function, it may describe the temporal behaviour of the “cancer-proneness phenotype” (CPF) as a quantitative continuous trait. Upcrossing a fixed level (“threshold”) u and reaching level zero are the extremes of the Gaussian process considered; it is assumed that they might be interpreted as the transformation of CPF into a “neoplastic disease phenotype” or as the non-proneness to cancer, respectively.


Author(s):  
Nabil I. Al-Najjar ◽  
Ramon Casadesus-Masanell ◽  
Emre Ozdenoren

2000 ◽  
Vol 13 (3) ◽  
pp. 207-238 ◽  
Author(s):  
Philippe Briand ◽  
René Carmona

In this paper, we give existence and uniqueness results for backward stochastic differential equations when the generator has a polynomial growth in the state variable. We deal with the case of a fixed terminal time, as well as the case of random terminal time. The need for this type of extension of the classical existence and uniqueness results comes from the desire to provide a probabilistic representation of the solutions of semilinear partial differential equations in the spirit of a nonlinear Feynman-Kac formula. Indeed, in many applications of interest, the nonlinearity is polynomial, e.g, the Allen-Cahn equation or the standard nonlinear heat and Schrödinger equations.


2007 ◽  
Vol 7 (4) ◽  
pp. 347-359 ◽  
Author(s):  
Gaurav Ameta ◽  
Joseph K. Davidson ◽  
Jami J. Shah

A new mathematical model for representing the geometric variations of lines is extended to include probabilistic representations of one-dimensional (1D) clearance, which arise from positional variations of the axis of a hole, the size of the hole, and a pin-hole assembly. The model is compatible with the ASME/ ANSI/ISO Standards for geometric tolerances. Central to the new model is a Tolerance-Map (T-Map) (Patent No. 69638242), a hypothetical volume of points that models the 3D variations in location and orientation for a segment of a line (the axis), which can arise from tolerances on size, position, orientation, and form. Here, it is extended to model the increases in yield that occur when maximum material condition (MMC) is specified and when tolerances are assigned statistically rather than on a worst-case basis; the statistical method includes the specification of both size and position tolerances on a feature. The frequency distribution of 1D clearance is decomposed into manufacturing bias, i.e., toward certain regions of a Tolerance-Map, and into a geometric bias that can be computed from the geometry of multidimensional T-Maps. Although the probabilistic representation in this paper is built from geometric bias, and it is presumed that manufacturing bias is uniform, the method is robust enough to include manufacturing bias in the future. Geometric bias alone shows a greater likelihood of small clearances than large clearances between an assembled pin and hole. A comparison is made between the effects of choosing the optional material condition MMC and not choosing it with the tolerances that determine the allowable variations in position.


2018 ◽  
Vol 2 (9) ◽  
pp. 693-705 ◽  
Author(s):  
Milena Rabovsky ◽  
Steven S. Hansen ◽  
James L. McClelland

Author(s):  
Dana J. Coombs ◽  
Paul J. Rullkoetter ◽  
Peter J. Laz

Soft tissue structures of the L4-L5 level of the human lumbar spine are represented in finite-element (FE) models, which are used to evaluate spine biomechanics and implant performance. These models typically use average properties; however, experimental testing reports variation up to 40% in ligament stiffness and even greater variability for annulus fibrosis (AF) properties. Probabilistic approaches enable consideration of the impact of intersubject variability on model outputs. However, there are challenges in directly applying the variability in measured load–displacement response of structures to a finite-element model. Accordingly, the objectives of this study were to perform a comprehensive review of the properties of the L4-L5 structures and to develop a probabilistic representation to characterize variability in the stiffness of spinal ligaments and parameters of a Holzapfel–Gasser–Ogden constitutive material model of the disk. The probabilistic representation was determined based on direct mechanical test data as found in the literature. Monte Carlo simulations were used to determine the uncertainty of the Holzapfel–Gasser–Ogden constitutive model. A single stiffness parameter was defined to characterize each ligament, with the anterior longitudinal ligament (ALL) being the stiffest, while the posterior longitudinal ligament and interspinous ligament (ISL) had the greatest variation. The posterior portion of the annulus fibrosis had the greatest stiffness and greatest variation up to 300% in circumferential loading. The resulting probabilistic representation can be utilized to include intersubject variability in biomechanics evaluations.


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