AQUAPORIN-2 AND -3: Representatives of Two Subgroups of the Aquaporin Family Colocalized in the Kidney Collecting Duct

1998 ◽  
Vol 60 (1) ◽  
pp. 199-220 ◽  
Author(s):  
S. Sasaki ◽  
K. Ishibashi ◽  
F. Marumo
Keyword(s):  
Collecting Duct ◽  
Kidney Collecting Duct ◽  
Aquaporin 2 ◽  
Aquaporin Family

scholarly journals Expression of VAMP-2-like protein in kidney collecting duct intracellular vesicles. Colocalization with Aquaporin-2 water channels.

1995 ◽  
Vol 96 (4) ◽  
pp. 1834-1844 ◽  
Author(s):  
S Nielsen ◽  
D Marples ◽  
H Birn ◽  
M Mohtashami ◽  
N O Dalby ◽  
...  
Keyword(s):  
Collecting Duct ◽  
Water Channels ◽  
Kidney Collecting Duct ◽  
Aquaporin 2 ◽  
Intracellular Vesicles

scholarly journals Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells

2019 ◽  
Vol 10 ◽  
Author(s):  
Shu-Ting Lin ◽  
Chia-Ching Ma ◽  
Kuang-Ting Kuo ◽  
Yin-Fang Su ◽  
Wei-Ling Wang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Collecting Duct ◽  
Kidney Collecting Duct ◽  
Aquaporin 2 ◽  
Duct Cells ◽  
Collecting Duct Cells

scholarly journals Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Water Channel Aquaporin-2 of Kidney Collecting Duct Cells

2004 ◽  
Vol 96 (3) ◽  
pp. 255-259 ◽  
Author(s):  
Kuniaki Takata ◽  
Yuki Tajika ◽  
Toshiyuki Matsuzaki ◽  
Takeo Aoki ◽  
Takeshi Suzuki ◽  
...  
Keyword(s):  
Drug Development ◽  
Molecular Mechanisms ◽  
Collecting Duct ◽  
Water Channel ◽  
Kidney Collecting Duct ◽  
Aquaporin 2 ◽  
Duct Cells ◽  
Collecting Duct Cells ◽  
Aquaporin Water Channel

scholarly journals Molecular mechanisms regulating aquaporin-2 in kidney collecting duct

2016 ◽  
Vol 311 (6) ◽  
pp. F1318-F1328 ◽  
Author(s):  
Hyun Jun Jung ◽  
Tae-Hwan Kwon
Keyword(s):  
Molecular Mechanisms ◽  
Collecting Duct ◽  
Water Channel ◽  
Peptide Hormone ◽  
Urine Concentration ◽  
The Body ◽  
Apical Plasma Membrane ◽  
Kidney Collecting Duct ◽  
Aquaporin 2 ◽  
Aqp2 Gene

The kidney collecting duct is an important renal tubular segment for regulation of body water homeostasis and urine concentration. Water reabsorption in the collecting duct principal cells is controlled by vasopressin, a peptide hormone that induces the osmotic water transport across the collecting duct epithelia through regulation of water channel proteins aquaporin-2 (AQP2) and aquaporin-3 (AQP3). In particular, vasopressin induces both intracellular translocation of AQP2-bearing vesicles to the apical plasma membrane and transcription of the Aqp2 gene to increase AQP2 protein abundance. The signaling pathways, including AQP2 phosphorylation, RhoA phosphorylation, intracellular calcium mobilization, and actin depolymerization, play a key role in the translocation of AQP2. This review summarizes recent data demonstrating the regulation of AQP2 as the underlying molecular mechanism for the homeostasis of water balance in the body.

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