Mapping the distribution of amobarbital sodium in the intracarotid Wada test by use of Tc-99m HMPAO with SPECT.

Radiology ◽  
1991 ◽  
Vol 178 (3) ◽  
pp. 847-850 ◽  
Author(s):  
P J Jeffery ◽  
L H Monsein ◽  
Z Szabo ◽  
J Hart ◽  
R S Fisher ◽  
...  
Keyword(s):  
2012 ◽  
Vol 23 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Jurriaan M. Peters ◽  
Meritxell Tomas-Fernandez ◽  
Michel J.A.M. van Putten ◽  
Tobias Loddenkemper

2017 ◽  
Vol 9 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Jörg Mauler ◽  
Irene Neuner ◽  
Georg Neuloh ◽  
Bruno Fimm ◽  
Frank Boers ◽  
...  

In the past, the eloquent areas could be deliberately localised by the invasive Wada test. The very rare cases of dissociated crossed speech areas were accidentally found based on the clinical symptomatology. Today functional magnetic resonance imaging (fMRI)-based imaging can be employed to non-invasively localise the eloquent areas in brain tumour patients for therapy planning. A 41-year-old, left-handed man with a low-grade glioma in the left frontal operculum extending to the insular cortex, tension headaches, and anomic aphasia over 5 months underwent a pre-operative speech area localisation fMRI measurement, which revealed the evidence of the transhemispheric disposition, where the dominant Wernicke speech area is located on the left and the Broca’s area is strongly lateralised to the right hemisphere. The outcome of the Wada test and the intraoperative cortico-subcortical stimulation mapping were congruent with this finding. After tumour removal, language area function was fully preserved. Upon the occurrence of brain tumours with a risk of impaired speech function, the rare dissociate crossed speech areas disposition may gain a clinically relevant meaning by allowing for more extended tumour removal. Hence, for its identification, diagnostics which take into account both brain hemispheres, such as fMRI, are recommended.


1966 ◽  
Vol 18 (2) ◽  
pp. 645-646 ◽  
Author(s):  
Barbara J. Powell ◽  
M. E. Ogle ◽  
L. K. Martin ◽  
D. K. Kamano

In studying the relationship between level of CS intensity (light) and drug condition (amobarbital sodium) in the acquisition of the conditioned avoidance response of the white rat in a jump-box task, data showed that both variables influenced avoidance performance. Although the over-all performance of drugged Ss was better than that of those given a placebo, primary differences occurred at 50,000 and 800,000 peak candles of CS intensity; performance of Ss under placebo showed a marked decline at 800,000 peak candles.


Author(s):  
Jacinta McElligott
Keyword(s):  

2004 ◽  
Vol 62 (3a) ◽  
pp. 582-587 ◽  
Author(s):  
Maria Joana Mäder ◽  
Bellkiss Wilma Romano ◽  
Luciano De Paola ◽  
Carlos Eduardo Soares Silvado

The Wada Test (WT) is part of the presurgical evaluation for refractory epilepsy. The WT is not standardized and the protocols differ in important ways, including stimulus type of material presented for memory testing, timing of presentations and methods of assessment. The aim of this study was to contribute to establish parameters for a WT to Brazilian population investigating the performance of 100 normal subjects, without medication. Two parallel models were used based on Montreal Procedure adapted from Gail Risse's (MEG-MN,EUA) protocol. The proportions of correct responses of normal subjects submitted to two parallel WT models were investigated and the two models were compared. The results showed that the two models are similar but significant differences among the stimulus type were observed. The results suggest that the stimulus type may influence the results of the WT and should be considered when constructing models and comparing different protocols.


1980 ◽  
Vol 69 (2) ◽  
pp. 161-162 ◽  
Author(s):  
Charles F. Flaherty ◽  
Cynthia D. Driscoll
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document