CS Intensity, Amobarbital Sodium and the Conditioned Avoidance Response

1966 ◽  
Vol 18 (2) ◽  
pp. 645-646 ◽  
Author(s):  
Barbara J. Powell ◽  
M. E. Ogle ◽  
L. K. Martin ◽  
D. K. Kamano
Keyword(s):  
Avoidance Response ◽  
Avoidance Performance ◽  
Conditioned Avoidance ◽  
Conditioned Avoidance Response ◽  
Drug Condition ◽  
Marked Decline ◽  
Amobarbital Sodium ◽  
The Relationship ◽  
Better Than

In studying the relationship between level of CS intensity (light) and drug condition (amobarbital sodium) in the acquisition of the conditioned avoidance response of the white rat in a jump-box task, data showed that both variables influenced avoidance performance. Although the over-all performance of drugged Ss was better than that of those given a placebo, primary differences occurred at 50,000 and 800,000 peak candles of CS intensity; performance of Ss under placebo showed a marked decline at 800,000 peak candles.

Effects of Amobarbital Sodium and Meprobamate on Acquisition of Conditioned Avoidance

1965 ◽  
Vol 17 (3) ◽  
pp. 691-694 ◽  
Author(s):  
Barbara J. Powell ◽  
Louis K. Martin ◽  
Dennis K. Kamano
Keyword(s):  
Avoidance Response ◽  
Avoidance Performance ◽  
Conditioned Avoidance ◽  
Activity Level ◽  
Albino Rats ◽  
General Activity Level ◽  
Amobarbital Sodium ◽  
Relationship Of ◽  
The Relationship ◽  
Increased Activity

The purpose of these experiments was to study the effects of two “fear-reducing” drugs, amobarbital sodium and meprobamate, on the acquisition of a conditioned avoidance response in albino rats, and how this response is related to general activity level and freezing behavior. Both drugs facilitated acquisition of the avoidance response and increased activity level as measured by the number of spontaneous inter-trial hurdle crossings. Thus, these results seemed at variance with Mowrer's theory regarding the relationship of fear to the avoidance response. However, the results were compatible with the theory that the relationship of performance to motivation is an inverted U-shaped function, which suggests that amobarbital and meprobamate exerted their facilitating effects on avoidance performance by obtunding the strong fear-freezing response which is known to be incompatible with the emission of the avoidance response.

Effects of Amobarbital on the Conditioned Emotional Response and Conditioned Avoidance Response

1966 ◽  
Vol 16 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Dennis K. Kamano ◽  
Louis K. Martin ◽  
Michael E. Ogle ◽  
Barbara J. Powell
Keyword(s):  
Avoidance Response ◽  
Emotional Response ◽  
Conditioned Emotional Response ◽  
Conditioned Avoidance ◽  
Conditioned Avoidance Response

scholarly journals Learning of a conditioned avoidance response by the pig

1976 ◽  
Vol 25 (3) ◽  
pp. 448-448
Author(s):  
R. DANTZER ◽  
P. MORMEDE ◽  
B. FAVRE
Keyword(s):  
Avoidance Response ◽  
Conditioned Avoidance ◽  
Conditioned Avoidance Response

scholarly journals The antipsychotic activity of alcoholic extract of Withania coagulans fruits in Swiss albino mice

2018 ◽  
Vol 7 (12) ◽  
pp. 2389
Author(s):  
Amit S. Kamdi ◽  
Sarika D. Kokane ◽  
Pankaj N. Bohra ◽  
Suvarna M. Kalambe
Keyword(s):  
Avoidance Response ◽  
Conditioned Avoidance ◽  
Conditioned Avoidance Response ◽  
P Value ◽  
Alcoholic Extract ◽  
Swiss Albino Mice ◽  
Withania Coagulans ◽  
Antipsychotic Activity ◽  
Albino Mice ◽  
Cns Effects

Background: Schizophrenia is one of the most distressing central nervous system (CNS) disorders. It is described by positive, negative and cognitive symptoms. These symptoms can be controlled by the antipsychotic medicines. The numerous antipsychotic medications used today are not lacking the adverse drug reactions. The Withania coagulans a susceptible species, is not explored much for its CNS effects except in late seventies. Therefore, it was thought worthwhile to investigate anti-psychotic activities of alcoholic extract of Withania coagulans fruits. The objective of the present study was to assess the antipsychotic activity of alcoholic extract of Withania coagulans fruits in Swiss albino mice by Cook’s Pole Climb Apparatus for conditioned avoidance response (CAR)Methods: Cook’s Pole Climb Apparatus for conditioned avoidance response was used for assessing the antipsychotic activity of the alcoholic extract of 200mg/kg, 500mg/kg and 1000mg/kg doses of Withania coagulans fruits.Results: There was statistically (p-value >0.05) no significant association between any of the 200mg/kg, 500mg/kg and 1000mg/kg doses of the alcoholic extracts of Withania coagulans fruits with antipsychotic activity in Swiss albino mice.Conclusions: Withania coagulans fruits alcoholic extract did not demonstrate antipsychotic activity in Swiss albino mice under standard conditions.

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