THE INFLUENCE OF DIET AND THE ANTERIOR PITUITARY GROWTH HORMONE ON THE GROWTH RATE OF ADOLESCENT RATS

1932 ◽  
Vol 99 (2) ◽  
pp. 379-390 ◽  
Author(s):  
A. Hughes Bryan ◽  
David W. Gaiser
Keyword(s):  
Growth Hormone ◽  
Growth Rate ◽  
Anterior Pituitary ◽  
Pituitary Growth Hormone ◽  
Adolescent Rats

scholarly journals The mobilization of lipid by anterior pituitary growth hormone

1953 ◽  
Vol 54 (3) ◽  
pp. 407-413 ◽  
Author(s):  
A. L. Greenbaum ◽  
Patricia McLean
Keyword(s):  
Growth Hormone ◽  
Anterior Pituitary ◽  
Pituitary Growth Hormone

Anterior Pituitary Growth Hormone (STH) and Pancreatic Secretion of Glucagon (HGF).

1953 ◽  
Vol 83 (4) ◽  
pp. 758-761 ◽  
Author(s):  
P. P. Foa ◽  
E. B. Magid ◽  
M. D. Glassman ◽  
H. R. Weinstein
Keyword(s):  
Growth Hormone ◽  
Pancreatic Secretion ◽  
Anterior Pituitary ◽  
Pituitary Growth Hormone

Galactopoietic Activity of Purified Anterior Pituitary Growth Hormone

Nature ◽  
1949 ◽  
Vol 164 (4180) ◽  
pp. 992-993 ◽  
Author(s):  
P. M. Cotes ◽  
J. A. Crichton ◽  
S. J. Folley ◽  
F. G. Young
Keyword(s):  
Growth Hormone ◽  
Anterior Pituitary ◽  
Pituitary Growth Hormone

ADMINISTRATION OF ANTERIOR PITUITARY GROWTH HORMONE TO RATS DURING COLD EXPOSURE

1963 ◽  
Vol 41 (1) ◽  
pp. 1449-1453
Author(s):  
John R. Beaton ◽  
T. Orme ◽  
J. Laufer ◽  
A. Turner
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Weight Gain ◽  
Cold Exposure ◽  
Anterior Pituitary ◽  
Body Weight Gain ◽  
Nitrogen Retention ◽  
Growing Rats ◽  
Pituitary Growth Hormone ◽  
Environmental Temperatures

Male, growing rats were injected daily with anterior pituitary growth hormone (3 mg/100 g body weight) and fed ad libitum for 7 days at environmental temperatures of 22 °C and 2–3 °C. Body weight gain, nitrogen retention, and four liver enzyme activities were measured. As observed previously, cold exposure retarded body weight gain and decreased nitrogen retention despite an increased food intake. These effects of cold were not eliminated by administration of growth hormone. The increased activities of liver arginase, alanine-glutamic transminase, and phosphate-activated glutaminase consequent upon cold exposure were not significantly affected by growth hormone although, at 22 °C, growth hormone decreased the activities of liver arginase and alanine-glutamic transaminase. Cold exposure eliminated the lowering effect of growth hormone on liver glutamic acid dehydrogenase activity observed at 22 °C. It is concluded that, under these conditions, growth hormone does not overcome the protein catabolic effects of cold exposure but rather, cold exposure eliminates the protein anabolic effects of the hormone.

Effects of a fragment of human growth hormone-releasing factor in normal and 'Little' mice

1985 ◽  
Vol 106 (1) ◽  
pp. 1-5 ◽  
Author(s):  
R. G. Clark ◽  
I. C. A. F. Robinson
Keyword(s):  
Growth Hormone ◽  
Growth Rate ◽  
Pituitary Gland ◽  
Human Growth Hormone ◽  
Anterior Pituitary ◽  
Human Growth ◽  
Body Growth ◽  
Stimulus Secretion Coupling ◽  
And Storage ◽  
Little Mouse

ABSTRACT The 'Little' mouse is characterized by a body growth rate 60% of normal due to a defect in the synthesis and storage of GH in the anterior pituitary gland. We have now investigated the effects of GH releasing factor (GRF) in these mice and in normal animals. The pituitary GH content in Little mice was only 4% of that in normal C57: +/+ mice, and was not affected by twice daily i.p. injections of human (h) GRF1-29NH2 (0·2−2 μg) for 14 days. This treatment also had no effect on body growth. In anaesthetized normal mice, single i.v. injections of 0·1 or 2 μg hGRF1-29NH2 released large amounts of GH into the plasma, whereas this peptide was ineffective in Little mice, whether or not they had been pretreated with GRF. Therefore, although pituitaries of Little mice contain significant amounts of GH, this pool is not releasable by GRF. This suggests that the dwarfism in Little mice may be partly due to a pituitary defect in GRF receptors or their stimulus-secretion coupling, rather than a deficiency in hypothalamic GRF. J. Endocr. (1985) 106, 1–5

ADMINISTRATION OF ANTERIOR PITUITARY GROWTH HORMONE TO RATS DURING COLD EXPOSURE

1963 ◽  
Vol 41 (6) ◽  
pp. 1449-1453 ◽  
Author(s):  
John R. Beaton ◽  
T. Orme ◽  
J. Laufer ◽  
A. Turner
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Weight Gain ◽  
Cold Exposure ◽  
Anterior Pituitary ◽  
Body Weight Gain ◽  
Nitrogen Retention ◽  
Growing Rats ◽  
Pituitary Growth Hormone ◽  
Environmental Temperatures

Male, growing rats were injected daily with anterior pituitary growth hormone (3 mg/100 g body weight) and fed ad libitum for 7 days at environmental temperatures of 22 °C and 2–3 °C. Body weight gain, nitrogen retention, and four liver enzyme activities were measured. As observed previously, cold exposure retarded body weight gain and decreased nitrogen retention despite an increased food intake. These effects of cold were not eliminated by administration of growth hormone. The increased activities of liver arginase, alanine-glutamic transminase, and phosphate-activated glutaminase consequent upon cold exposure were not significantly affected by growth hormone although, at 22 °C, growth hormone decreased the activities of liver arginase and alanine-glutamic transaminase. Cold exposure eliminated the lowering effect of growth hormone on liver glutamic acid dehydrogenase activity observed at 22 °C. It is concluded that, under these conditions, growth hormone does not overcome the protein catabolic effects of cold exposure but rather, cold exposure eliminates the protein anabolic effects of the hormone.

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