scholarly journals Effect of muscle mass on V˙o 2kinetics at the onset of work

2001 ◽  
Vol 90 (2) ◽  
pp. 461-468 ◽  
Author(s):  
Shunsaku Koga ◽  
Thomas J. Barstow ◽  
Tomoyuki Shiojiri ◽  
Tetsuo Takaishi ◽  
Yoshiyuki Fukuba ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Ventilatory Threshold ◽  
Slow Component ◽  
Cycle Ergometer ◽  
Muscle Recruitment ◽  
Heavy Exercise ◽  
Mean Response Time ◽  
Heavy Work ◽  
Exercise Transitions ◽  
Recruitment Patterns

The dependence of O2 uptake (V˙o 2) kinetics on the muscle mass recruited under conditions when fiber and muscle recruitment patterns are similar following the onset of exercise has not been determined. We developed a motorized cycle ergometer that facilitated one-leg (1L) cycling in which the electromyographic (EMG) profile of the active muscles was not discernibly altered from that during two-leg (2L) cycling. Six subjects performed 1L and 2L exercise transitions from unloaded cycling to moderate [<ventilatory threshold (VT)] and heavy (>VT) exercise. The 1L condition yielded kinetics that was unchanged from the 2L condition [the phase 2 time constants (τ1, in s) for <VT were as follows: 1L = 16.8±8.4 (SD), 2L = 18.4 ± 8.1, P > 0.05; for >VT: 1L = 26.8 ± 12.0; 2L = 27.8 ± 16.1, P > 0.05]. The overall V˙o 2 kinetics (mean response time) was not significantly different for the two exercise conditions. However, the gain of the fast component (the amplitude/work rate) during the 1L exercise was significantly higher than that for the 2L exercise for both moderate and heavy work rates. The slow-component responses evident for heavy exercise were temporally and quantitatively unaffected by the 1L condition. These data demonstrate that, when leg muscle recruitment patterns are unchanged as assessed by EMG analysis, on-transient V˙o 2 kinetics for both moderate and heavy exercise are not dependent on the muscle mass recruited.

Acceleration of V˙o 2kinetics in heavy submaximal exercise by hyperoxia and prior high-intensity exercise

1997 ◽  
Vol 83 (4) ◽  
pp. 1318-1325 ◽  
Author(s):  
Maureen Macdonald ◽  
Preben K. Pedersen ◽  
Richard L. Hughson
Keyword(s):  
High Intensity ◽  
Ventilatory Threshold ◽  
Slow Component ◽  
Submaximal Exercise ◽  
High Intensity Exercise ◽  
Total Change ◽  
Group Of Seven ◽  
Mean Response Time ◽  
Exercise Transitions ◽  
The Mean

MacDonald, Maureen, Preben K. Pedersen, and Richard L. Hughson. Acceleration ofV˙o 2 kinetics in heavy submaximal exercise by hyperoxia and prior high-intensity exercise. J. Appl. Physiol. 83(4): 1318–1325, 1997.—We examined the hypothesis that O2 uptake (V˙o 2) would change more rapidly at the onset of step work rate transitions in exercise with hyperoxic gas breathing and after prior high-intensity exercise. The kinetics ofV˙o 2 were determined from the mean response time (MRT; time to 63% of total change inV˙o 2) and calculations of O2 deficit and slow component during normoxic and hyperoxic gas breathing in one group of seven subjects during exercise below and above ventilatory threshold (VT) and in another group of seven subjects during exercise above VT with and without prior high-intensity exercise. In exercise transitions below VT, hyperoxic gas breathing did not affect the kinetic response of V˙o 2 at the onset or end of exercise. At work rates above VT, hyperoxic gas breathing accelerated both the on- and off-transient MRT, reduced the O2 deficit, and decreased theV˙o 2 slow component from minute 3 to minute 6 of exercise, compared with normoxia. Prior exercise above VT accelerated the on-transient MRT and reduced theV˙o 2 slow component from minute 3 to minute 6 of exercise in a second bout of exercise with both normoxic and hyperoxic gas breathing. However, the summated O2 deficit in the second normoxic and hyperoxic steps was not different from that of the first steps in the same gas condition. Faster on-transient responses in exercise above, but not below, VT with hyperoxia and, to a lesser degree, after prior high-intensity exercise above VT support the theory of an O2 transport limitation at the onset of exercise for workloads >VT.

Cardiovascular and Oxygen Uptake Kinetics During Sequential Heavy Cycling Exercises

2003 ◽  
Vol 28 (2) ◽  
pp. 283-298 ◽  
Author(s):  
Stéphane Perrey ◽  
Jodie Scott ◽  
Laurent Mourot ◽  
Jean-Denis Rouillon
Keyword(s):  
Cardiac Output ◽  
Oxygen Uptake ◽  
Time Constant ◽  
Impedance Cardiography ◽  
Ventilatory Threshold ◽  
Slow Component ◽  
Oxygen Uptake Kinetics ◽  
Cycle Ergometer ◽  
Fast Component ◽  
Heavy Exercise

The purpose of the present study was to assess the relationship between the rapidity of increased oxygen uptake [Formula: see text] and increased cardiac output (CO) during heavy exercise. Six subjects performed repeated bouts on a cycle ergometer above the ventilatory threshold (∼80% of peak [Formula: see text]) separated by 10-min recovery cycling at 35% peak [Formula: see text]. [Formula: see text] was determined breath-by-breath and CO was determined continuously by impedance cardiography. CO and [Formula: see text] values were significantly higher during the 2-min period preceding the second bout. The overall responses for [Formula: see text] and CO were significantly related and were faster during the second bout. Prior heavy exercise resulted in a significant increase in the amplitude of the fast component of [Formula: see text] with no change in the time constant and a decrease in the slow component. Under these circumstances, the amplitude of the fast component was more sensitive to prior heavy exercise than was the associated time constant. Key words: impedance cardiography, exercise transitions, cardiac output, prior exercise

scholarly journals Effects of prior heavy exercise on phase II pulmonary oxygen uptake kinetics during heavy exercise

2000 ◽  
Vol 89 (4) ◽  
pp. 1387-1396 ◽  
Author(s):  
Mark Burnley ◽  
Andrew M. Jones ◽  
Helen Carter ◽  
Jonathan H. Doust
Keyword(s):  
Oxygen Uptake ◽  
Phase Ii ◽  
Slow Component ◽  
Exercise Bout ◽  
Oxygen Uptake Kinetics ◽  
Cycle Ergometer ◽  
Moderate Exercise ◽  
Heavy Exercise ◽  
Mean Response Time ◽  
The Mean

We tested the hypothesis that heavy-exercise phase II oxygen uptake (V˙o 2) kinetics could be speeded by prior heavy exercise. Ten subjects performed four protocols involving 6-min exercise bouts on a cycle ergometer separated by 6 min of recovery: 1) moderate followed by moderate exercise; 2) moderate followed by heavy exercise; 3) heavy followed by moderate exercise; and 4) heavy followed by heavy exercise. The V˙o 2 responses were modeled using two (moderate exercise) or three (heavy exercise) independent exponential terms. Neither moderate- nor heavy-intensity exercise had an effect on the V˙o 2 kinetic response to subsequent moderate exercise. Although heavy-intensity exercise significantly reduced the mean response time in the second heavy exercise bout (from 65.2 ± 4.1 to 47.0 ± 3.1 s; P < 0.05), it had no significant effect on either the amplitude or the time constant (from 23.9 ± 1.9 to 25.3 ± 2.9 s) of theV˙o 2 response in phase II. Instead, this “speeding” was due to a significant reduction in the amplitude of the V˙o 2 slow component. These results suggest phase II V˙o 2 kinetics are not speeded by prior heavy exercise.

scholarly journals Effect of a 15% Increase in Preferred Pedal Rate on Time to Exhaustion During Heavy Exercise

2004 ◽  
Vol 29 (2) ◽  
pp. 146-156 ◽  
Author(s):  
Xavier Nesi ◽  
Laurent Bosquet ◽  
Serge Berthoin ◽  
Jeanne Dekerle ◽  
Patrick Pelayo
Keyword(s):  
Exercise Tolerance ◽  
Ventilatory Threshold ◽  
Slow Component ◽  
Time To Exhaustion ◽  
Heavy Exercise ◽  
Pedal Rate ◽  
Competitive Cyclists ◽  
Text Response ◽  
Specific Formula ◽  
The Difference

The aim of this study was to evaluate the effect of a 15% increase in preferred pedal rate (PPR) on both time to exhaustion and pulmonary O2 uptake [Formula: see text] response during heavy exercise. Seven competitive cyclists underwent two constant-power tests (CPT) at a power output that theoretically requires 50% of the difference in [Formula: see text] between the second ventilatory threshold and [Formula: see text]max (PΔ50). Each cyclist cycled a CPT at PPR (CPTPPR) and a CPT at +15% of PPR (CPT+15%) in a randomized order. The average PPR value was 94 ± 4 rpm, and time to exhaustion was significantly longer in CPTPPR compared with CPT+15% (465 ± 139 vs. 303 ± 42 s, respectively; p = 0.01). A significant decrease in [Formula: see text] values in the first minutes of exercise and a significant increase in [Formula: see text] slow component was reported in CPT+15% compared with CPTPPR. These data indicate that the increase of 15% PPR was associated with a decrease in exercise tolerance and a specific [Formula: see text] response, presumably due to an increase of negative muscular work, internal work, and an altering of motor unit recruitment patterns. Key words: aerobic demand, cadence, cyclists, exercise tolerance, pedaling frequency

V˙o 2 kinetics in the horse during moderate and heavy exercise

1997 ◽  
Vol 83 (4) ◽  
pp. 1235-1241 ◽  
Author(s):  
I. Langsetmo ◽  
G. E. Weigle ◽  
M. R. Fedde ◽  
H. H. Erickson ◽  
T. J. Barstow ◽  
...  
Keyword(s):  
Time Constant ◽  
Slow Component ◽  
Venous Blood ◽  
Exponential Model ◽  
Mixed Venous Blood ◽  
Phase 2 ◽  
Heavy Exercise ◽  
Two Phase ◽  
Treadmill Testing ◽  
Exercise Transitions

Langsetmo, I., G. E. Weigle, M. R. Fedde, H. H. Erickson, T. J. Barstow, and D. C. Poole.V˙o 2 kinetics in the horse during moderate and heavy exercise. J. Appl. Physiol. 83(4): 1235–1241, 1997.—The horse is a superb athlete, achieving a maximal O2 uptake (∼160 ml ⋅ min−1 ⋅ kg−1) approaching twice that of the fittest humans. Although equine O2 uptake (V˙o 2) kinetics are reportedly fast, they have not been precisely characterized, nor has their exercise intensity dependence been elucidated. To address these issues, adult male horses underwent incremental treadmill testing to determine their lactate threshold (Tlac) and peakV˙o 2(V˙o 2 peak), and kinetic features of theirV˙o 2 response to “square-wave” work forcings were resolved using exercise transitions from 3 m/s to a below-Tlac speed of 7 m/s or an above-Tlac speed of 12.3 ± 0.7 m/s (i.e., between Tlac andV˙o 2 peak) sustained for 6 min. V˙o 2 and CO2 output were measured using an open-flow system: pulmonary artery temperature was monitored, and mixed venous blood was sampled for plasma lactate.V˙o 2 kinetics at work levels below Tlac were well fit by a two-phase exponential model, with a phase 2 time constant (τ1 = 10.0 ± 0.9 s) that followed a time delay (TD1 = 18.9 ± 1.9 s). TD1 was similar to that found in humans performing leg cycling exercise, but the time constant was substantially faster. For speeds above Tlac, TD1 was unchanged (20.3 ± 1.2 s); however, the phase 2 time constant was significantly slower (τ1 = 20.7 ± 3.4 s, P < 0.05) than for exercise below Tlac. Furthermore, in four of five horses, a secondary, delayed increase inV˙o 2 became evident 135.7 ± 28.5 s after the exercise transition. This “slow component” accounted for ∼12% (5.8 ± 2.7 l/min) of the net increase in exercise V˙o 2. We conclude that, at exercise intensities below and above Tlac, qualitative features ofV˙o 2 kinetics in the horse are similar to those in humans. However, at speeds below Tlac the fast component of the response is more rapid than that reported for humans, likely reflecting different energetics of O2utilization within equine muscle fibers.

Letters to the Editor

1998 ◽  
Vol 85 (4) ◽  
pp. 1593-1600
Author(s):  
Guido Ferretti
Keyword(s):  
Slow Component ◽  
Oxygen Uptake Kinetics ◽  
Work Rate ◽  
Hot Water ◽  
Muscle Temperature ◽  
Appreciable Effect ◽  
Heavy Exercise ◽  
Letters To The Editor ◽  
Heavy Work ◽  
The Difference

The following is the abstract of the article discussed in the subsequent letter: Koga, Shunsaku, Tomoyuki Shiojiri, Narihiko Kondo, and Thomas J. Barstow. Effect of increased muscle temperature on oxygen uptake kinetics during exercise. J. Appl. Physiol. 83(4): 1333–1338, 1997.—To test whether increased muscle temperature (Tm) would improve O2 uptake (V˙o 2) kinetics, seven men performed transitions from rest to a moderate work rate [below the estimated lactate threshold (LTest)] and a heavy work rate (V˙o 2 = 50% of the difference between LTest and peakV˙o 2) under conditions of normal Tm (N) and increased Tm (H), produced by wearing hot water-perfused pants before exercise. Quadriceps Tm was significantly higher in H, but rectal temperature was similar for the two conditions. There were no significant differences in the amplitudes of the fast component ofV˙o 2 or in the time constants of the on and off transients for moderate and heavy exercise between the two conditions. The increment inV˙o 2 between the 3rd and 6th min of heavy exercise was slightly but significantly smaller for H than for N. These data suggest that elevated Tm before exercise onset, which would have been expected to increase O2delivery and off-loading to the muscle, had no appreciable effect on the fast exponential component ofV˙o 2 kinetics (invariant time constant). These data further suggest that elevated Tm does not contribute to the slow component ofV˙o 2 during heavy exercise.

Slow component of O2 uptake during heavy exercise: adaptation to endurance training

1995 ◽  
Vol 79 (3) ◽  
pp. 838-845 ◽  
Author(s):  
C. J. Womack ◽  
S. E. Davis ◽  
J. L. Blumer ◽  
E. Barrett ◽  
A. L. Weltman ◽  
...  
Keyword(s):  
Heart Rate ◽  
Power Output ◽  
Slow Component ◽  
Exercise Bout ◽  
Cycle Ergometer ◽  
O2 Uptake ◽  
Heavy Exercise ◽  
Absolute Power ◽  
Exercise Adaptation ◽  
Male Subjects

Seven untrained male subjects [age 25.6 +/- 1.5 (SE) yr, peak O2 uptake (VO2) 3.20 +/- 0.19 l/min] trained on a cycle ergometer 4 days/wk for 6 wk, with the absolute training workload held constant for the duration of training. Before and at the end of each week of training, the subjects performed 20 min of constant-power exercise at a power designed to elicit a pronounced slow component of VO2 (end-exercise VO2-VO2 at minute 3 of exercise) in the pretraining session. An additional 20-min exercise bout was performed after training at this same absolute power output during which epinephrine (Epi) was infused at a rate of 100 ng.kg-1.min-1 between minutes 10 and 20. After 2 wk of training, significant decreases in VO2 slow component, end-exercise VO2, blood lactate ([La-] and glucose concentrations, plasma Epi ([Epi]) and norepinephrine concentrations, ventilation (VE), and heart rate (HR) were observed (P < 0.05). Although the rapid attenuation of the VO2 slow component coincided temporally with reductions in plasma [Epi], blood [La-], and VE, the infusion of Epi after training significantly increased plasma [Epi] (delta 2.22 ng/ml), blood [La-] (delta 2.4 mmol/l) and VE (delta 10.0 l/min) without any change in exercise VO2. We therefore conclude that diminution of the VO2 slow component with training is attributable to factors other than the reduction in plasma [Epi], blood [La-] and VE.

scholarly journals Effect of pedal rate on primary and slow-component oxygen uptake responses during heavy-cycle exercise

2003 ◽  
Vol 94 (4) ◽  
pp. 1501-1507 ◽  
Author(s):  
Jamie S. M. Pringle ◽  
Jonathan H. Doust ◽  
Helen Carter ◽  
Keith Tolfrey ◽  
Andrew M. Jones
Keyword(s):  
Power Output ◽  
Ventilatory Threshold ◽  
Slow Component ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Motor Units ◽  
Primary Component ◽  
Heavy Exercise ◽  
Cycle Exercise ◽  
Pedal Rate

We hypothesized that a higher pedal rate (assumed to result in a greater proportional contribution of type II motor units) would be associated with an increased amplitude of the O2 uptake (V˙o 2) slow component during heavy-cycle exercise. Ten subjects (mean ± SD, age 26 ± 4 yr, body mass 71.5 ± 7.9 kg) completed a series of square-wave transitions to heavy exercise at pedal rates of 35, 75, and 115 rpm. The exercise power output was set at 50% of the difference between the pedal rate-specific ventilatory threshold and peakV˙o 2, and the baseline power output was adjusted to account for differences in the O2 cost of unloaded pedaling. The gain of the V˙o 2primary component was significantly higher at 35 rpm compared with 75 and 115 rpm (mean ± SE, 10.6 ± 0.3, 9.5 ± 0.2, and 8.9 ± 0.4 ml · min−1 · W−1, respectively; P < 0.05). The amplitude of theV˙o 2 slow component was significantly greater at 115 rpm (328 ± 29 ml/min) compared with 35 rpm (109 ± 30 ml/min) and 75 rpm (202 ± 38 ml/min) ( P < 0.05). There were no significant differences in the time constants or time delays associated with the primary and slow components across the pedal rates. The change in blood lactate concentration was significantly greater at 115 rpm (3.7 ± 0.2 mM) and 75 rpm (2.8 ± 0.3 mM) compared with 35 rpm (1.7 ± 0.4 mM) ( P < 0.05). These data indicate that pedal rate influences V˙o 2 kinetics during heavy exercise at the same relative intensity, presumably by altering motor unit recruitment patterns.

V˙o 2 kinetics and the O2 deficit in heavy exercise

2000 ◽  
Vol 88 (4) ◽  
pp. 1407-1412 ◽  
Author(s):  
S. E. Bearden ◽  
R. J. Moffatt
Keyword(s):  
Slow Component ◽  
Work Rate ◽  
New Method ◽  
Heavy Exercise ◽  
Delayed Onset ◽  
Final Steady State ◽  
Exercise Transitions ◽  
The Difference ◽  
Traditional Manner ◽  
O2 Deficit

The purpose of this study was to examine a new method for calculating the O2 deficit that considered the O2 uptake (V˙o 2) kinetics during exercise as two separate phases in light of previous research in which it was shown that the traditional O2 deficit calculation overestimated the recovery O2 consumption (ROC). Eight subjects completed exercise transitions between unloaded cycling and 25% (heavy, H) or 50% (very heavy, VH) of the difference between the lactic acid threshold (LAT) and peakV˙o 2 for 8 min. The O2 deficit, calculated in the traditional manner, was significantly greater than the measured ROC for both above-LAT exercises: 4.03 ± 1.01 vs. 2.63 ± 0.80 (SD) liters for VH and 2.36 ± 0.91 vs. 1.74 ± 0.63 liters for H for the O2deficit vs. ROC ( P < 0.05). When the kinetics were viewed as two separate components with independent onsets, the calculated O2 deficit (2.89 ± 0.79 and 1.71 ± 0.70 liters for VH and H, respectively) was not different from the measured ROC ( P < 0.05). Subjects also performed the same work rate for only 3 min. These data, from bouts terminated before the slow component could contribute appreciably to the overallV˙o 2 response, show that the O2 requirement during the transition is less than the final steady state for the work rate, as evidenced by symmetry between the O2 deficit and ROC. This new method of calculating the O2 deficit more closely reflects the expected O2 deficit-ROC relationship (i.e., ROC ≥ O2deficit). Therefore, estimation of the O2 deficit during heavy exercise transitions should consider the slow component ofV˙o 2 as an additional deficit component with delayed onset.

Dynamic Responses of Oxygen Uptake at the Onset and End of Moderate and Heavy Exercise in Trained Subjects

2004 ◽  
Vol 29 (1) ◽  
pp. 32-44 ◽  
Author(s):  
Christophe Cleuziou ◽  
Stéphane Perrey ◽  
Fabio Borrani ◽  
Anne Marie Lecoq ◽  
Robin Candau ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Ventilatory Threshold ◽  
Slow Component ◽  
Exponential Model ◽  
Dynamic Responses ◽  
Parameter Estimates ◽  
Heavy Exercise ◽  
Cycling Exercise ◽  
Trained Subjects ◽  
Key Words Oxygen Uptake

Inconsistencies about dynamic asymmetry between the on- and off-transient responses in [Formula: see text] are found in the literature. Therefore the purpose of this study was to examine [Formula: see text]on-and off-transients during moderate- and heavy-intensity cycling exercise in trained subjects. Ten men underwent an initial incremental test for the estimation of ventilatory threshold (VT) and, on different days, two bouts of square-wave exercise at moderate (< VT) and heavy (> VT) intensities. [Formula: see text] kinetics in exercise and recovery were better described by a single exponential model (< VT), or by a double exponential with two time delays (> VT). For moderate exercise, we found a symmetry of [Formula: see text] kinetics between the on- and off-transients (i.e., fundamental component), consistent with a system manifesting linear control dynamics. For heavy exercise, a slow component superimposed on the fundamental phase was expressed in both the exercise and recovery, with similar parameter estimates. But the on-transient values of the time constant were appreciably faster than the associated off-transient, and independent of the work rate imposed (< VT and > VT). Our results do not support a dynamically linear system model of [Formula: see text] during cycling exercise in the heavy-intensity domain. Key words: oxygen uptake kinetics, on- and off-transients, slow component

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