scholarly journals Endoscopic Management of Gastric Varices: Efficacy and Outcomes of Gluing with N-Butyl-2-Cyanoacrylate in a North American Patient Population

2008 ◽  
Vol 22 (11) ◽  
pp. 931-936 ◽  
Author(s):  
PJ Belletrutti ◽  
J Romagnuolo ◽  
RJ Hilsden ◽  
F Chen ◽  
B Kaplan ◽  
...  

BACKGROUND: Gastric variceal bleeding is associated with significant morbidity and mortality in patients with portal hypertension. Outside of North America, gastric variceal injection of N-butyl-2-cyanoacrylate has been shown to be safe and effective. The majority of studies on this mode of therapy are in Asian populations in which the etiology of portal hypertension differs from North America.AIM: To assess the safety and efficacy of gastric variceal glue injection in a North American population.METHODS: Consecutive patients that underwent glue injection of gastric varices in the Calgary Health Region from 2001 to 2006 were assessed.RESULTS: Thirty-four patients (19 men, 15 women) underwent a total of 47 separate gluing procedures. Of those presenting with active bleeding at endoscopy, immediate hemostasis was achieved in 93.8% of patients. Rebleeding within 48 h of gluing was observed after four procedures. Gastric varices were eradicated in 84.0% of cases. Complications included superior mesenteric vein thrombosis in one patient. Twenty-eight (82.4%) patients were alive at the end of follow-up. The treatment failure-related mortality rate was 2.1%.CONCLUSIONS: The present study is one of the few to assess the role of gastric variceal gluing in a North American population. Glue injection with cyanoacrylate is safe and effective in the treatment of bleeding gastric varices.

2011 ◽  
Vol 57 (14) ◽  
pp. E1924
Author(s):  
Ana Laynez Carnicero ◽  
Michael A. Gaglia ◽  
Kohei Wakabayashi ◽  
Rafael Romaguera ◽  
Gabriel Maluenda ◽  
...  

2007 ◽  
Vol 17 (9-10) ◽  
pp. 869
Author(s):  
C. Feener ◽  
P. Kang ◽  
E. Estrella ◽  
B. Darras ◽  
A. Amato ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Said A. Al-Busafi ◽  
Peter Ghali ◽  
Philip Wong ◽  
Marc Deschenes

Cirrhosis is the leading cause of portal hypertension worldwide, with the development of bleeding gastroesophageal varices being one of the most life-threatening consequences. Endoscopy plays an indispensible role in the diagnosis, staging, and prophylactic or active management of varices. With the expected future refinements in endoscopic technology, capsule endoscopy may one day replace traditional gastroscopy as a diagnostic modality, whereas endoscopic ultrasound may more precisely guide interventional therapy for gastric varices.


The Auk ◽  
2002 ◽  
Vol 119 (3) ◽  
pp. 676-684 ◽  
Author(s):  
Michel Robert ◽  
Réjean Benoit ◽  
Jean-Pierre L. Savard

Abstract Little is known of the eastern North American population of Barrow's Goldeneyes (Bucephala islandica), which was recently listed as “of special concern” in Canada. In 1998 and 1999, we marked 18 adult males wintering along the St. Lawrence River, Québec, with satellite transmitters to document their breeding, molting, and wintering distribution and phenology, and to describe timing and routes of their spring, molt, and fall migrations. Thirteen males moved inland from the St. Lawrence River to breed; the spring migration averaged 5.9 days, and birds arrived on breeding areas on average 9 May. All breeding areas were inland, on the north shore of the St. Lawrence River estuary and gulf. Breeding areas averaged 64.8 km from the St. Lawrence corridor. Males stayed on their respective breeding area a mean of 34.5 days, and left on average 11 June. Twelve males were tracked to their molting areas, one of which stayed on its wintering area until 5 June and flew directly to its molting area. Their molt migration averaged 18.6 days, and the mean arrival date on molting areas was 30 June. All molting areas were located north and averaged 986 km from breeding areas. Four males molted in Hudson Bay, four in Ungava Bay, two in northern Labrador, one on Baffin Island, and one inland, near the Québec–Labrador border. The mean length of stay on the molting areas was 105.3 days, and the mean date of departure from molting areas was 4 October. All goldeneyes for which the radio still functioned during fall migration returned to winter in the St. Lawrence River estuary, on average 6 November. Our results refute the idea that the main breeding area of the eastern North American population of Barrow's Goldeneyes is located in northern Québec and Labrador and rather indicate that it is in the boreal forest just north of the St. Lawrence River estuary and gulf. They also indicate that Barrow's Goldeneye males undertake a genuine molt migration, and highlight the importance of molting areas because birds stayed there approximately four months each year.


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