scholarly journals Does Hypothyroidism Affect Gastrointestinal Motility?

2009 ◽  
Vol 2009 ◽  
pp. 1-7 ◽  
Author(s):  
Olga Yaylali ◽  
Suna Kirac ◽  
Mustafa Yilmaz ◽  
Fulya Akin ◽  
Dogangun Yuksel ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Gastrointestinal Motility ◽  
Primary Hypothyroidism ◽  
Dynamic Imaging ◽  
Control Group ◽  
Esophageal Transit ◽  
Gastric Emptying Scintigraphy ◽  
Esophageal Scintigraphy ◽  
Gastric Emptying Time ◽  
Healthy Females

Background. Gastrointestinal motility and serum thyroid hormone levels are closely related. Our aim was to analyze whether there is a disorder in esophagogastric motor functions as a result of hypothyroidism.Materials and Methods. The study group included 30 females (mean age ± SE 45.17 ± 2.07 years) with primary hypothyroidism and 10 healthy females (mean age ± SE 39.40 ± 3.95 years). All cases underwent esophagogastric endoscopy and scintigraphy. For esophageal scintigraphy, dynamic imaging of esophagus motility protocol, and for gastric emptying scintigraphy, anterior static gastric images were acquired.Results. The mean esophageal transit time (52.56 ± 4.07 sec for patients; 24.30 ± 5.88 sec for controls;P=.02) and gastric emptying time (49.06 ± 4.29 min for the hypothyroid group; 30.4 ± 4.74 min for the control group;P=.01) were markedly increased in cases of hypothyroidism.Conclusion. Hypothyroidism prominently reduces esophageal and gastric motor activity and can cause gastrointestinal dysfunction.

Gastric emptying time in patients with primary hypothyroidism

1997 ◽  
Vol 9 (9) ◽  
pp. 901-904 ◽  
Author(s):  
Hakk Kahraman ◽  
Nadir Kaya ◽  
Arif Demirçal ◽  
Irem Bernay ◽  
Fulya Tanyeri
Keyword(s):  
Gastric Emptying ◽  
Primary Hypothyroidism ◽  
Gastric Emptying Time ◽  
Emptying Time

Effect of percutaneous endoscopic gastrostomy on gastrointestinal motility: evaluation by gastric-emptying scintigraphy

2008 ◽  
Vol 29 (6) ◽  
pp. 562-567 ◽  
Author(s):  
Hideyuki Wakamatsu ◽  
Shigeki Nagamachi ◽  
Ryuichi Nishii ◽  
Kazutaka Higaki ◽  
Keiichi Kawai ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Gastrointestinal Motility ◽  
Percutaneous Endoscopic Gastrostomy ◽  
Gastric Emptying Scintigraphy ◽  
Endoscopic Gastrostomy

scholarly journals Influence of electroacupuncture on the points BP6 and E36 regarding gastric motility in Wistar rats

2017 ◽  
Vol 38 (2) ◽  
pp. 1071
Author(s):  
Guilherme Albuquerque de Oliveira Cavalcanti ◽  
Marlete Brum Cleff ◽  
Fábio Da Silva e Silva ◽  
Luiz Filipe Dame Schuch ◽  
Marina De Mattos Ferrasso ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Gastric Motility ◽  
Wistar Rats ◽  
Negative Control Group ◽  
Negative Control ◽  
Radiographic Examination ◽  
Control Group ◽  
Orogastric Tube ◽  
Gastric Emptying Time ◽  
Emptying Time

The study aimed to evaluate by radiographic examination the action of electroacupuncture on gastric motility in experimental animals. We used 24 Wistar rats, three months old, that received five metallic spheres, via orogastric tube (OT), with 2mL of barium contrast, followed by treatments: electroacupuncture points E36 and BP6 (T1); electroacupuncture in stitches (T2); sterile distilled water OT (T3); metoclopramide OT (T4). After treatment, serial radiographs, hourly, were made to follow the gastric emptying time of the spheres in rats. By analyzing the time of exit of the first sphere, animals in the group T1 had an average of 3h30min; at T2 the average was higher 6 hours; in T3 was 5h18min, and T4 showed an average of 4h36min. The action of electroacupuncture was comparable to the action of metoclopramide, which is know to increase peristalsis, whereas the response of the Shan group (T2) was close to the negative control group. Considering the results it was concluded that electroacupuncture at points predetermined significantly increases gastric peristalsis, reducing gastric emptying time in rats, may be an option for the treatment of motility disorders.

scholarly journals Gastrointestinal Motility, Mucosal Mast Cell, and Intestinal Histology in Rats: Effect of Prednisone

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Maysa Bruno de Lima ◽  
Loyane Almeida Gama ◽  
Andrieli Taise Hauschildt ◽  
Denize Jussara Rupolo Dall’Agnol ◽  
Luciana Aparecida Corá ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Mast Cells ◽  
Gastrointestinal Motility ◽  
Experimental Studies ◽  
Control Group ◽  
Mucosal Mast Cell ◽  
Intestinal Histology ◽  
Adult Rats ◽  
Small Intestinal Transit ◽  
Mucosal Mast Cells

Our aim was to verify the effects of prednisone related to gastrointestinal motility, intestinal histology, and mucosal mast cells in rats. Two-month-old male Wistar rats were randomly assigned to control group (vehicle) animals receiving saline 0.9% (n=7) or treated orally with 0.625 mg/kg/day of prednisone (n=7) or 2.5 mg/kg/day of prednisone (n=7) during 15 days. Mast cells and other histologic analyses were performed in order to correlate to gastric emptying, cecum arrival, and small intestine transit evaluated by Alternating Current Biosusceptometry. Results showed that prednisone in adult rats increased the frequency of gastric contractions, hastened gastric emptying, slowed small intestinal transit, and reduced mucosal mast cells. Histologically, the treatment with both doses of prednisone decreased villus height, whereas longitudinal and circular muscles and crypt depth were not affected. These findings indicate an impairment of intestinal absorption which may be linked to several GI dysfunctions and symptoms. The relationship between gastrointestinal motor disorders and cellular immunity needs to be clarified in experimental studies since prednisone is one of the most prescribed glucocorticoids worldwide.

scholarly journals Caffeine and Gastric Emptying Time in Very Preterm Neonates

2020 ◽  
Vol 9 (6) ◽  
pp. 1676
Author(s):  
Antonios K. Gounaris ◽  
Ioanna N. Grivea ◽  
Maria Baltogianni ◽  
Eleni Gounari ◽  
George Antonogeorgos ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Preterm Neonates ◽  
Control Group ◽  
Cross Sectional ◽  
Very Preterm ◽  
Caffeine Treatment ◽  
Study Results ◽  
Significant Difference ◽  
Gastric Emptying Time ◽  
Emptying Time

Background: Caffeine has been commonly used for prevention and treatment of apnea-related symptoms in premature infants. However, its side effects have not been thoroughly studied. We investigated whether caffeine affects gastric motility in very-preterm (VP) neonates. Methods: The study is a randomized crossover clinical trial. Twenty-two neonates with mean birth weight (BW) (standard deviation—SD) 1077 (229) g and mean gestational age (GA) (SD) 28.6 (2.1) weeks were recruited. Each neonate had its gastric emptying time checked twice with ultrasound assessment of changes in antral cross sectional area (ACSA). All neonates were sequentially allocated to the caffeine group (A) and the control group (B). Complications from the gastrointestinal tract were documented throughout the study. Results: Statistically significant difference was found with regards to the gastric emptying time [median, (range)] between caffeine and control group (p = 0.040). Additionally, in the neonates with BW 1000–1500 g and GA ≥ 28 weeks, the gastric emptying time (minutes) was significantly longer during caffeine treatment [44.5 (36–68.2)] and [40 (34.5–66.5)] respectively, as compared to the gastric emptying time during no caffeine treatment [27 (24.2–30)] (p = 0.002) and [27 (24.5–30)] (p = 0.001). The incidence of gastrointestinal (GI) complications was significantly greater in neonates receiving caffeine [6 (27.%)] as compared with those without caffeine treatment [1 (4.6%)] (p = 0.039). Conclusions: During caffeine treatment, a significantly delayed gastric emptying time was noted in all study neonates, especially in these with BW 1000–1500 g and those with GA ≥ 28 weeks. Further larger studies are necessary in order to confirm this interesting finding.

scholarly journals The Effect of Specific Oral Nutritional Supplements Compared to Tea with Sugar on Gastric Emptying Time, Blood Glucose Level, and Hunger Response in Healthy Adults

2017 ◽  
Vol 1 (1) ◽  
pp. 13
Author(s):  
Stella Evangeline Bela ◽  
Luciana Budiati Sutanto ◽  
Jacob Pandelaki
Keyword(s):  
Blood Glucose ◽  
Gastric Emptying ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Intervention Group ◽  
Healthy Adults ◽  
Control Group ◽  
Oral Nutritional Supplements ◽  
Gastric Emptying Time ◽  
Emptying Time

Introduction: The objective of this study was to compare gastric emptying time, hunger response, and blood glucose level after drinking specific oral nutritional supplements (S-ONS) to tea with sugar in healthy adults.Methods: This study was a clinical, parallel, random allocation, and single-blind trial. This study was conducted at Cipto Mangunkusumo General Hospital, Jakarta. The subjects were 12 healthy adults divided into 2 groups: intervention group (n = 6) and control group (n = 6). Patients in the intervention group received 200 mL S-ONS (200 kcal, 18% protein, 20% fat and 62% carbohydrate) and control group received 200 mL of tea with 10 grams of sugar (40 kcal). Gastric volume was measured using 2D-sonography every 30 minutes. Blood glucose level was measured using blood peripheral sample. Hunger response was measured using visual analog scale (VAS).Results: Gastric emptying time in the intervention group was <90 minutes, and in the control group <60 minutes. Blood glucose level was increased in the intervention group and decreased in control group. Hunger response was decreased in intervention group and increased in control group.Conclusion: Gastric emptying time after either drinking S-ONS and drinking tea with sugar in healthy adults subjects were less than 2 hours. Patients receiving S-ONS had significantly higher blood glucose level and were less hungry than the control group. 

A modified sonographic technique for assessment of gastric emptying of liquid

2003 ◽  
Vol 44 (3) ◽  
pp. 340-342 ◽  
Author(s):  
J. F. Pedersen
Keyword(s):  
Gastric Emptying ◽  
Repeated Measurements ◽  
Intraindividual Variation ◽  
Ultrasound Technique ◽  
Liquid Meal ◽  
Ultrasound Monitoring ◽  
Gastric Emptying Time ◽  
The Mean ◽  
Antral Area ◽  
Emptying Time

Purpose: Ultrasound scanning is replacing scintigraphy in studies of gastric emptying of liquid, but both have considerable day-to-day variability. This study describes a modified ultrasound technique for assessing gastric emptying of liquid, and evaluates the inter- and intraindividual variation in emptying time. Material and Methods: On different days, each of 12 healthy volunteers had meals of 350 ml broth. The antral area was measured at sonography 5 times before the meal as a baseline, and every 1–4 min after the meal. The time until the antral area had decreased to 150% of baseline (T150) was determined and used as surrogate expression of gastric emptying time. Results: The mean T150 for a broth meal was 12.6 min (range 5–21) and 13.5 min (6–23) (first and second meal, respectively). The standard deviation of the differences between the 12 pairs of repeated measurements was 3.1 min and the coefficient of variation was 24%. Conclusion: Ultrasound monitoring of antral size after a liquid meal is a well suited method for assessing gastric emptying of liquid.

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