scholarly journals Ulcerative Granular Cell Tumor: A Clinicopathological and Immunohistochemical Study

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Mohamed El-Khalawany ◽  
Al-Sadat Mosbeh ◽  
Fatma Abd-Al Salam ◽  
Amany Abou-Bakr
Keyword(s):  
Differential Diagnosis ◽  
Granular Cell Tumor ◽  
Immunohistochemical Study ◽  
Granular Cell ◽  
Cell Tumor ◽  
Granular Cytoplasm ◽  
Solitary Ulcer ◽  
Cutaneous Ulcer ◽  
Ulcerative Lesions ◽  
Dermal Infiltrate

Granular cell tumor (GCT) is uncommonly presented with cutaneous ulcer. We examined the clinicopathological and immunohistochemical features of this ulcerative form in fourteen cases that may raise the awareness of this variant. The study included 11 males and 3 females with a mean age 31.5 ± 7.42 years. All cases were presented with large solitary ulcer with indurated base, elevated border, skin colored margin, and necrotic floor. Twelve lesions were located on the extremities and two lesions on the genital region. Histologically, the lesions showed dermal infiltrate composed of large polygonal cells with granular cytoplasm and characteristic infiltration of the dermal muscles in all cases. Immunostaining showed positive reaction for S100 (14/14), NSE (14/14), CD68 (5/14), and Vimentin (7/14) while HMB45, CK, EMA, and Desmin were negative. We hope that this paper increases the awareness of ulcerative GCT and consider it in the differential diagnosis of ulcerative lesions.

scholarly journals Immunohistochemical Study of Granular Cell Tumor of Tongue.

1993 ◽  
Vol 86 (5) ◽  
pp. 687-690 ◽  
Author(s):  
Masaji Lee ◽  
Tetsuo Saeki ◽  
Shinya Ohashi ◽  
Shin Kawai ◽  
Akihide Ichimura ◽  
...  
Keyword(s):  
Granular Cell Tumor ◽  
Immunohistochemical Study ◽  
Granular Cell ◽  
Cell Tumor

scholarly journals Laryngeal Granular Cell Tumor; Rare Location

2011 ◽  
Vol 54 (1) ◽  
pp. 41-43
Author(s):  
Sedat Aydın ◽  
Arif Şanlı ◽  
Özlem Çelebi ◽  
Emin Ayduran ◽  
Gecer Melin
Keyword(s):  
Differential Diagnosis ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Complete Surgical Resection ◽  
Submucosal Lesions ◽  
Neurogenic Origin ◽  
Rare Location ◽  
Posterior Glottis

Granular cell tumors are benign subcutaneous or submucosal lesions of neurogenic origin. In this case study one patient was diagnosed and treated successfully with complete surgical resection of a laryngeal granular cell tumor that was originated from the left arytenoid region that very rare location. There is no evidence of recurrence 2 years after surgery. Granular cell tumors should be considered in the differential diagnosis of laryngeal masses, particularly in the posterior glottis.

scholarly journals Granular Cell Tumor of the Tongue: A Rare Case Presentation of a 14 Years Old Girl

2021 ◽  
pp. 1-2
Author(s):  
Mansour Nacouzi ◽  
Keyword(s):  
Granular Cell Tumor ◽  
Benign Neoplasm ◽  
Granular Cell ◽  
Cell Tumor ◽  
Lateral Border ◽  
Case Presentation ◽  
Granular Cytoplasm ◽  
The Right ◽  
Sixth Decade ◽  
Mobile Tongue

Granular cell tumor or Abrikossoff ’s tumor is an infrequent tumor that can arise in most organs, and especially in the ENT area. It is a usually benign neoplasm, that can lead to a misdiagnose of malignancy. It affects both sex, between the fourth and the sixth decade. We present in this report a case of a 14 years old girl with a slowly growing lesion on the right lateral border of the mobile tongue. The biopsy showed a proliferation of large cells with a granular cytoplasm that expressed two immunohistochemistry markers: CD68 and S100 antibodies. Surgical resection was completed with a one centimeter margin.The rare issue about this case is the age of presentation: the age of the patient is 14, whereas this tumor usually affects adult patients.

scholarly journals Granular cell tumor of the tongue: An electron microscopical and immunohistochemical study.

1990 ◽  
Vol 32 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Hiroyuki OKADA ◽  
Hirotsugu YAMAMOTO ◽  
Tomonori KAWANA ◽  
Takao KATOH ◽  
Yukishige KOZAWA ◽  
...  
Keyword(s):  
Granular Cell Tumor ◽  
Immunohistochemical Study ◽  
Granular Cell ◽  
Cell Tumor ◽  
Electron Microscopical

Granular Cell Tumors of the Larynx

1976 ◽  
Vol 85 (4) ◽  
pp. 504-507 ◽  
Author(s):  
Harvey L. Coates ◽  
Thomas J. McDonald ◽  
Kenneth D. Devine ◽  
Louis H. Weiland
Keyword(s):  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Posterior Portion ◽  
Pseudoepitheliomatous Hyperplasia

Granular cell tumors of the larynx are relatively uncommon, always benign, and most commonly located in the posterior portion of the larynx. They are easily identified and should be differentiated from other lesions. A possible problem in the differential diagnosis is the presence of pseudoepitheliomatous hyperplasia, which overlies the granular cell tumor and which may mimic squamous cell carcinoma. Careful histopathologic differentiation is important because the laryngeal granular cell lesion should be managed conservatively, with transoral local excision usually being adequate. The histogenesis of these lesions remains in doubt, with a neural or epithelial derivation being the most likely possibility.

scholarly journals Granular cell tumor in the geriatric patient. Clinical, histological and immunohistochemical study

2015 ◽  
pp. S18-18
Author(s):  
P Martinez Balayo ◽  
D Perez Lopez ◽  
R Luces Gonzalez ◽  
MA Penamaria Mallon ◽  
E Otero Rey ◽  
...  
Keyword(s):  
Geriatric Patient ◽  
Granular Cell Tumor ◽  
Immunohistochemical Study ◽  
Granular Cell ◽  
Cell Tumor
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