scholarly journals Steroid Cell Ovarian Neoplasm, Not Otherwise Specified: A Case Report and Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Paul Singh ◽  
Frank Deleon ◽  
Ralph Anderson

Background. Steroid cell ovarian tumors, not otherwise specified, represent a unique cause of female virilization. Most commonly encountered in premenopausal women, these tumors can exist throughout a women’s lifetime, from before puberty until after menopause.Case. Steroid cell, not otherwise specified, was diagnosed in a 70-year-old female significant for hirsutism. The patient demonstrated elevated total testosterone levels with normal gonadotropins, DHEA, and DHEA-S levels. CT imaging revealed a right ovarian mass and subsequent laparoscopic right oophorectomy yielded clinical improvement promptly.Conclusion. Virilization in females can occur based on ovarian or adrenal pathology. In terms of ovarian-based female virilization, many tumors exist that may induce women to demonstrate masculine features, such as pure Sertoli, pure Leydig, Sertoli-Leydig combinations, and gynandroblastomas. Each of these tumor types possesses a unique histologic pattern that allows for pathologic identification after removal. A rare source of ovarian-based female virilization is steroid cell neoplasms, not otherwise specified, that do not demonstrate these specific histologic characteristics and thus represent a diagnosis of exclusion after other causes of ovarian-based female virilization have been ruled out.

2010 ◽  
Vol 30 (5) ◽  
pp. 1732-1736
Author(s):  
Canan KELTEN ◽  
Nagihan YALÇIN ◽  
Şermin ÇOBAN ◽  
Erkan ALATAŞ ◽  
Metin AKBULUT

2021 ◽  
Vol 13 (4) ◽  
pp. 405-410
Author(s):  
M Mabrouk ◽  
D Raimondo ◽  
M Cofano ◽  
L Cocchi ◽  
R Paradisi ◽  
...  

Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. It is a common finding in premenopausal women and commonly affects the gastrointestinal tract, especially the rectosigmoid tract. Small bowel involvement is rare and usually asymptomatic making diagnosis difficult. Here we report an uncommon case of exophytic ileal endometriosis surgically treated. Detailed pre-operative counselling on the risk of ileal surgery should always be considered in all cases with endometriosis requiring surgery. We also present a review of the literature regarding the clinical presentation, diagnosis, and treatment of this challenging condition.


2020 ◽  
pp. 180-181
Author(s):  
Amrita Prasad ◽  
Aravind. K.R.

Xanthogranulomatous inflammation is a rare type of granulomatous inflammation and the cause is yet to be identified. In this pathology, the affected organ undergoes lysis and is replaced by dense inflammatory cell infiltrates. Here is a case of a 42 year old woman presenting with lower abdominal lump and pain for 3 months, clinical examination revealed a suspicion of tubo-ovarian mass, which on further hematological and radiological examination gave the impression of an ovarian neoplasm. Finally Histopathological study of the resected specimen came out as Xanthogranulomatous oophoritis (XO).


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Jessica Lee ◽  
Veena S. John ◽  
Sharon X. Liang ◽  
Catherine A. D’Agostino ◽  
Andrew W. Menzin

We report a case of malignant ovarian steroid cell tumor not otherwise specified (NOS) in a 47-year-old female who presented with hirsutism, virilization, and amenorrhea. At the time of laparotomy, the tumor had already spread to the pelvic cul-de-sac. She underwent a total hysterectomy, bilateral salpingo-oophorectomy, and tumor resection with no residual disease. She received three cycles of bleomycin, etoposide, and cisplatin (BEP) and is now free of disease 24 months after surgery. Literature review of ovarian steroid cell tumors NOS including clinicopathological features and clinical management was performed.


2013 ◽  
Vol 137 (4) ◽  
pp. 576-579 ◽  
Author(s):  
Justin Hardin ◽  
Jerad M. Gardner ◽  
Maria I. Colomé ◽  
Patricia Chévez-Barrios

A 58-year-old woman presented with a cystic skin lesion. Microscopic examination showed an intradermal cyst lined by acanthotic squamous epithelium with squamous eddies and compact hyperkeratosis, and changes typical of verrucous lesions. Mature sebaceous cells and dendritic melanocytes were present as well. To our knowledge, this is the first report of a verrucous cyst with areas of sebaceous differentiation and melanocytes. Verrucous cysts are well-known, benign lesions with a clear histologic pattern. Histologically, they resemble verruca vulgaris with acanthosis, hypergranulosis, dense keratohyaline granules, and viral cytopathic effects seen. Until now, melanocytes and mature sebaceous cells in the cyst lining have not been reported. We do not feel that these findings alter the expected benign nature of this lesion. Instead, we report this case to suggest the possible adnexal embryonic origin, given the presence of sebaceous cells and dendritic melanocytes that support this histologic lineage in our specific case.


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