scholarly journals Skin Perfusion Pressure Is a Prognostic Factor in Hemodialysis Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Shingo Hatakeyama ◽  
Masaaki Saito ◽  
Kumiko Ishigaki ◽  
Hayato Yamamoto ◽  
Akiko Okamoto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Overall Survival ◽  
Lower Limb ◽  
Poor Prognosis ◽  
Perfusion Pressure ◽  
Hemodialysis Patients ◽  
Smoking History ◽  
Skin Perfusion ◽  
Skin Perfusion Pressure ◽  
Independent Risk Factors

Peripheral arterial disease (PAD) is common in hemodialysis patients and predicts a poor prognosis. We conducted a prospective cohort study to identify risk factors for PAD including skin perfusion pressure (SPP) in hemodialysis patients. The cohort included 373 hemodialysis patients among 548 patients who received hemodialysis at Oyokyo Kidney Research Institute, Hirosaki, Japan from August 2008 to December 2010. The endpoints were lower limb survival (peripheral angioplasty or amputation events) and overall survival of 2 years. Our results showed that <70 mmHg SPP was a poor prognosis for the lower limb survival and overall survival. We also identified age, history of cardiovascular disease, presence of diabetes mellitus, smoking history, and SPP < 70 mmHg as independent risk factors for lower limb survival and overall survival. Then, we constructed risk criteria using the significantly independent risk factors. We can clearly stratify lower limb survival and overall survival of the hemodialysis patients into 3 groups. Although the observation period is short, we conclude that SPP value has the potential to be a risk factor that predicts both lower limb survival and the prognosis of hemodialysis patients.

scholarly journals Examination of a skin perfusion pressure measurement method for the detection of lower limb peripheral arterial disease in hemodialysis patients

2021 ◽  
Vol 54 (3) ◽  
pp. 123-129
Author(s):  
Takuya Kamino ◽  
Mayumi Shibuya ◽  
Yuki Ohmae ◽  
Shigeru Nishikawa ◽  
Kiyoshi Tsurusaki ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Pressure Measurement ◽  
Lower Limb ◽  
Measurement Method ◽  
Perfusion Pressure ◽  
Arterial Disease ◽  
Hemodialysis Patients ◽  
Skin Perfusion ◽  
Skin Perfusion Pressure ◽  
Peripheral Arterial

scholarly journals Skin perfusion pressure predicts mortality in hemodialysis patients: long term follow-up

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Nanami Kida ◽  
Shunro Ageta ◽  
Yasunori Tsujimoto ◽  
Kiyoko Maehara ◽  
Masayuki Nagahara ◽  
...  
Keyword(s):  
Perfusion Pressure ◽  
Hemodialysis Patients ◽  
Skin Perfusion ◽  
Long Term Follow Up ◽  
Skin Perfusion Pressure

Assessment of Lower Limb Ischemia With Measurement of Skin Perfusion Pressure in Patients on Hemodialysis

2007 ◽  
Vol 11 (3) ◽  
pp. 196-201 ◽  
Author(s):  
Masaru Shimazaki ◽  
Takayuki Matsuki ◽  
Kazuaki Yamauchi ◽  
Michihiro Iwata ◽  
Hiroshi Takahashi ◽  
...  
Keyword(s):  
Lower Limb ◽  
Perfusion Pressure ◽  
Limb Ischemia ◽  
Lower Limb Ischemia ◽  
Skin Perfusion ◽  
Skin Perfusion Pressure

scholarly journals Diabetes mellitus indicate poor prognosis in uterine serous cancer patients

2021 ◽  
Author(s):  
Yunyun Liu ◽  
Jing Li ◽  
Zhibo Cheng ◽  
Guocai Xu ◽  
Yongpai Peng ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Overall Survival ◽  
Prognostic Factors ◽  
Poor Prognosis ◽  
Cox Regression ◽  
Figo Stage ◽  
Chi Square ◽  
Institutional Review ◽  
Independent Risk Factors

Abstract Purpose. We aimed to find prognostic factors for uterine serous cancer(USC) patients in a retrospective study.Methods. 51 USC patients between 2010-2020 were enrolled. All pathological specimens were reviewd. The research protocol was approved by Institutional Review Board and all patients were informed consent before the study began. Statistics were done using SPSS 25.0, T test and chi-square analyses were used to compare differences, the overall survival(OS) was estimated with Kaplan-Meier(KM) analysis, univariate and multivariate Cox regression analyses were utilized to find prognostic factors.Results. The median overall survival(OS) and progressive free survival(PFS) were 75.94 and 63.49 months, respectively. Diagnosed with diabetes mellitus(P=0.006, HR=6.792, 95%CI=1.726-26.722) and CA125＞28U/ml(P=0.006, HR=7.136, 95%CI=1.780-28.607) before surgery were independent risk factors for OS, advanced FIGO stage(P=0.001, HR=10.628, 95%CI=2.894-39.026) and DM(P=0.003, HR=6.327, 95%CI=1.875-21.354) were independent factors for PFS. Age≤52, , tumor size≥2.5cm and cervical mucosal infiltration may indicate poor prognosis but were not independent risk factors. Hypertension patients with routine medical treatment tend to survive longer, but there was no statistical differences in OS and PFS compared to patients with normal blood pressure.Conclusion. In addition to surgical and adjuvant treatments, gynecologists should focus more on the comorbid conditions of USC patiens, especially for DM.

scholarly journals TERT Mutations Correlated With the Prognosis of Patients With Hepatitis B-Related Hepatocellular Carcinoma Underwent Curative Hepatectomy

2021 ◽  
Author(s):  
Kangjian Song ◽  
Junyu Huo ◽  
Fu He ◽  
Qingwei Zhu ◽  
Liqun Wu
Keyword(s):  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Overall Survival ◽  
Hepatitis B ◽  
Poor Prognosis ◽  
Early Recurrence ◽  
Single Factor ◽  
Risk Factors For Recurrence ◽  
Independent Risk Factors ◽  
Curative Hepatectomy

Abstract Background To explore the value of TERT mutations in predicting the early recurrence and prognosis of hepatitis B-related hepatocellular carcinoma (HCC) patients underwent curative hepatectomy.Methods A total of 81 patients with hepatitis B-related HCC were enrolled and all patients underwent curative hepatectomy. Associations were sought between TERT mutations and recurrence rate within 2 years after hepatectomy, time to progress (TTP) and overall survival (OS).Results TERT mutations (HR: 2.985, 95%CI: 1.158-7.692, p=0.024) and Barcelona clinic liver (BCLC) stage B (HR: 3.326, 95%CI: 1.019-10.856, p=0.046) were independent risk factors for recurrence within 2 years after hepatectomy. Patients with a TERT mutation had poor TTP (p=0.003) and OS (p=0.013) than others. TERT mutations (HR: 2.245, 95%CI: 1.185-4.252, p=0.013) and BCLC stage B (HR: 2.132, 95%CI: 1.082-4.198, p=0.029) were independent risk factors for poor TTP after curative hepatectomy. A predictive model based on TERT mutations and BCLC stage had better ability to predict early recurrence after hepatectomy of HCC patients than any single factor (AUC: 0.688 vs. 0.639, 0.688 vs. 0.607, respectively). Patients with both TERT mutations and BCLC stage B had poorer TTP and OS than others (p=0.001, p<0.001, respectively).Conclusion TERT mutations had ability to predict early recurrence and poor prognosis for hepatitis B-related HCC patients underwent curative hepatectomy.

scholarly journals What are the Survival Factors in Surgically Resected Synchronous Multiple Primary Lung Cancers: A Retrospective Study

2020 ◽  
Author(s):  
Haichao Li ◽  
Kai Wang ◽  
Xingxing Zhang ◽  
Rong Chen ◽  
Jian Zhao
Keyword(s):  
Risk Factors ◽  
Overall Survival ◽  
Lymph Node ◽  
Independent Risk Factor ◽  
Complete Resection ◽  
Tnm Stage ◽  
Smoking History ◽  
Node Dissection ◽  
Multiple Primary ◽  
Independent Risk Factors

Abstract Background: With the popularization of high-resolution computed tomography (HRCT), the detection rate of synchronous multiple primary lung cancer (SMPLC) is increasing. We retrospectively analyzed the surgical results of SMPLC patients in our hospital to determine the best treatment, surgical prognosis and survival analysis.Methods: A total of 78 SMPLC patients met the diagnostic criteria underwent complete resection and lymph node dissection or sampling without any preoperative induction therapy in the Department of Thoracic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University. We analyzed the postoperative survival rate, and further studied the relationship between survival rates and sex, age, preoperative symptoms, tumor location, tumor number, tumor size, lymph node metastasis, TNM stage, surgical type, surgical frequency, histopathologic types, vascular infiltration, visceral pleural invasion and postoperative therapy.Results: Among 78 patients, the 1-,2-,3-,4- and 5-year disease free survival (DFS) rates were 93.42%, 86.84%, 77.78%, 62.96%, and 60.00%, respectively, while the 1-,2-,3-,4- and 5-year overall survival (OS) rates were 94.73%, 92.11%, 82.22%, 77.78%, and 65.00%, respectively. TNM stage of the largest tumor (II:HR=7.40,III:9.01,p=0.002) was an independent risk factor for DFS. Smoking history (HR=4.34,p=0.039) and TNM stage of the largest tumor (II:HR=9.38,III:9.42,p=0.003) were independent risk factors for overall survival.Conclusions: First, SMPLC is different from intrapulmonary metastasis and its clinical stage is also different from the 8th (2015) edition TNM classification for lung cancer. Second, when pulmonary function permits, surgery (complete resection and lymph node dissection) is a significantly beneficial treatment for patients with SMPLC. Third, TNM stage of the largest tumor (II:HR=7.40,III:9.01,p=0.002) was an independent risk factor for DFS. Smoking history (HR=4.34,p=0.039) and TNM stage of the largest tumor (II:HR=9.38,III:9.42,p=0.003) were independent risk factors for overall survival.

scholarly journals Effects of the Ankle-brachial Blood Pressure Index and Skin Perfusion Pressure on Mortality in Hemodialysis Patients

2013 ◽  
Vol 52 (21) ◽  
pp. 2417-2421 ◽  
Author(s):  
Yumi Otani ◽  
Shigeru Otsubo ◽  
Naoki Kimata ◽  
Mari Takano ◽  
Takayuki Abe ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Perfusion Pressure ◽  
Hemodialysis Patients ◽  
Brachial Blood Pressure ◽  
Skin Perfusion ◽  
Pressure Index ◽  
Skin Perfusion Pressure
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