scholarly journals Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of the Pancreas in a Porcine Model

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Monica Gaidhane ◽  
Ioana Smith ◽  
Kristi Ellen ◽  
Jeremy Gatesman ◽  
Nagy Habib ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
High Frequency ◽  
Porcine Model ◽  
Tissue Injury ◽  
Pancreatic Head ◽  
Minimal Amount ◽  
Coagulative Necrosis ◽  
Ultrasound Guided ◽  
Distal Pancreas ◽  
Minimal Evidence

Backgrounds. Limited effective palliative treatments exist for pancreatic cancer which includes surgery or chemotherapy. Radiofrequency ablation (RFA) uses high frequency alternating current to ablate diseased tissue and has been used to treat various tumors. In this study, we evaluated a prototype probe adjusted to the EUS-needle to perform EUS-RFA to permit coagulative necrosis in the pancreas.Methods. Five Yucatan pigs underwent EUS-guided radiofrequency ablation of the head of their pancreas. Using an EUS-needle, RFA was applied with 6 mm and then 10 mm of the probe exposed at specific wattage for preset durations.Results. Only one pig showed moderate levels of pancreatitis (20% proximal pancreatitis). The other animals showed much lower areas of tissue damage. In 3 of the 5 pigs, the proximal pancreas showed greater levels of tissue injury than the distal pancreas, consistent with the proximity of the tissue to the procedure site. In 1 pig, both proximal and distal pancreas showed minimal pancreatitis (1%). There was minimal evidence of fat necrosis in intra-pancreatic and/or extra-pancreatic adipose tissue.Conclusion. EUS-guided RFA of the pancreatic head with the monopolar probe through a 19-gauge needle was well tolerated in 5 Yucatan pigs and with minimal amount of pancreatitis.

Sa1531 Endoscopic Ultrasound Guided Radiofrequency Ablation (EUS-RFA) of the Pancreas in a Porcine Model: A Novel Palliative Option?

2012 ◽  
Vol 75 (4) ◽  
pp. AB193
Author(s):  
Michel Kahaleh ◽  
Monica Gaidhane ◽  
Ioana B. Smith ◽  
Kristi Ellen ◽  
Jeremy J. Gatesman ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Endoscopic Ultrasound ◽  
Porcine Model ◽  
Ultrasound Guided

Endoscopic ultrasound-guided lymph node ablation with a novel radiofrequency ablation probe: feasibility study in an acute porcine model

Endoscopy ◽  
2014 ◽  
Vol 46 (05) ◽  
pp. 411-415 ◽  
Author(s):  
Amrita Sethi ◽  
Mark Ellrichmann ◽  
Shantiswaroop Dhar ◽  
Klaus-Gerd Hadeler ◽  
Erich Kahle ◽  
...  
Keyword(s):  
Lymph Node ◽  
Radiofrequency Ablation ◽  
Feasibility Study ◽  
Endoscopic Ultrasound ◽  
Porcine Model ◽  
Ultrasound Guided

scholarly journals Endoscopic ultrasound-guided radiofrequency ablation of pancreatic neuroendocrine tumors: a case series

2020 ◽  
Vol 08 (12) ◽  
pp. E1754-E1758
Author(s):  
Germana de Nucci ◽  
Nicola Imperatore ◽  
Enzo Domenico Mandelli ◽  
Franca di Nuovo ◽  
Corrado d’Urbano ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Neuroendocrine Tumors ◽  
Endoscopic Ultrasound ◽  
Therapeutic Option ◽  
Case Series ◽  
Pancreatic Head ◽  
Complete Disappearance ◽  
Pancreatic Neuroendocrine Tumors ◽  
Ultrasound Guided ◽  
Effective Therapeutic Option

Abstract Background and study aims Surgery is the considered the therapeutic cornerstone for pancreatic neuroendocrine tumors (P-NETs), although burdened by high risk of significant adverse events. Recently, endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) has been described for P-NETs. We aimed to evaluate the effectiveness and safety of EUS-RFA for treatment of P-NETs. Patients and methods We prospectively included all consecutive patients with P-NET ≤ 20 mm who were treated with EUS-RFA and were followed-up for at least 12 months. Results Ten patients (5 males, mean age 78.6 years, mean body mass index 28.2) with 11 P-NETs (mean size 14.5 mm; range 9 – 20 mm) localized in the pancreatic head (3 lesions), pancreatic body (5 lesions), and tail (3 lesions) underwent complete EUS ablation with one session of RFA. Complete ablation of P-NET was reached using a single-session RFA with a mean of 2.3 treatment applications per session. At both 6 – and 12-months computed tomography scans, all the patients had complete disappearance of lesions with radiological normalization. Regarding safety, only two cases of mild abdominal pain were recorded in two subjects with pancreatic head lesion, which were effectively treated with analgesics. The mean duration of hospital stay was 4 days (range 3 – 7 days). Conclusions EUS-RFA is effective and safe in treating P-NETs. It may be considered an effective therapeutic option in the treatment of small P-NETs independently from their functional status.

Leberzellkarzinom – Radiofrequenzablation: Welches Bildgebungsverfahren ist effektiver?

2019 ◽  
Vol 24 (04) ◽  
pp. 163-164
Author(s):  
Cornelia Fietz
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Comparative Effectiveness ◽  
Percutaneous Radiofrequency Ablation ◽  
Ultrasound Guided ◽  
Medicare Patients ◽  
Us Dollar

Huo J et al. Comparative Effectiveness of Computed Tomography-Versus Ultrasound-Guided Percutaneous Radiofrequency Ablation Among Medicare Patients 65 Years of Age or Older With Hepatocellular Carcinoma. Value Health 2019; 22(3):284–292 Die Inzidenz des Leberzellkarzinoms hat sich in den letzen 20 Jahren mehr als verdoppelt. 2018 wurden in den USA mehr als 31 600 neue Fälle registriert, knapp die Hälfte dieser Patienten war älter als 65 Jahre. Die damit verbundenen jährlichen Kosten werden auf 455 Millionen US Dollar geschätzt. Für fortgeschrittene, inoperable Fälle steht die Radiofrequenzablation als Therapieoption zur Verfügung, die Ultraschall- oder Computertomographie-gestützt durchgeführt werden kann. Die Autoren vergleichen die Effektivität beider Bildgebungstechniken für das Verfahren.

Mo1268 Endoscopic Ultrasound Guided Radiofrequency Ablation (EUS-RFA): Initial Assessment of Safety and Efficacy

2017 ◽  
Vol 85 (5) ◽  
pp. AB484 ◽  
Author(s):  
Tom Malikowski ◽  
Ferga C. Gleeson ◽  
Matthew Block ◽  
Suresh T. Chari ◽  
Barham K. Abu Dayyeh ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Endoscopic Ultrasound ◽  
Initial Assessment ◽  
Ultrasound Guided ◽  
Safety And Efficacy

scholarly journals Ultrasound-guided thermal radiofrequency ablation to treat refractory knee and hip pain: Outcomes of a case series

2021 ◽  
Vol 28 ◽  
pp. 221049172110033
Author(s):  
Ismael Carneiro ◽  
Joana Silva ◽  
Tiago Lopes ◽  
José Luís Carvalho
Keyword(s):  
Radiofrequency Ablation ◽  
Pain Control ◽  
Case Series ◽  
Hip Pain ◽  
Ultrasound Guided ◽  
Symptomatic Knee ◽  
Pain Outcomes

A number of options are currently available to treat symptomatic knee and hip pain. Among them, there is the use of thermal radiofrequency ablation. It is a more recent technique and we still have a lack regarding safety and effectiveness. In this report, we briefly present a case series of patients with refractory knee and hip pain, treated with thermal radiofrequency ablation, where we discuss the results in safety and effectiveness, concerning not only the pain control, but also the return to participation in activities.

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