scholarly journals Nanobiosensors Based on Localized Surface Plasmon Resonance for Biomarker Detection

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
Yoochan Hong ◽  
Yong-Min Huh ◽  
Dae Sung Yoon ◽  
Jaemoon Yang

Localized surface plasmon resonance (LSPR) is induced by incident light when it interacts with noble metal nanoparticles that have smaller sizes than the wavelength of the incident light. Recently, LSPR-based nanobiosensors were developed as tools for highly sensitive, label-free, and flexible sensing techniques for the detection of biomolecular interactions. In this paper, we describe the basic principles of LSPR-based nanobiosensing techniques and LSPR sensor system for biomolecule sensing. We also discuss the challenges using LSPR nanobiosensors for detection of biomolecules as a biomarker.

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 23990-23998 ◽  
Author(s):  
Gaoling Liang ◽  
Zhongjun Zhao ◽  
Yin Wei ◽  
Kunping Liu ◽  
Wenqian Hou ◽  
...  

A simple, label-free and cost-effective localized surface plasmon resonance (LSPR) immunosensing method was developed for detection of alpha-fetoprotein (AFP).


2016 ◽  
Vol 52 (79) ◽  
pp. 11799-11802 ◽  
Author(s):  
Ruyan Li ◽  
Rong Yan ◽  
Jianchun Bao ◽  
Wenwen Tu ◽  
Zhihui Dai

In this work, a novel photoelectrochemical biosensing strategy was designed for cell assay under 630 nm (red light) excitation.


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