Pulmonary Mucus Gland Adenomas: Are They Always of Endobronchial Localization?

Mucus gland adenoma is an extremely rare benign lung tumor, presumed to arise from the bronchial mucus glands; it is a TTF-1 negative tumor, centrally located, causing the clinical manifestations of obstruction. We report a TTF-1 negative mucus gland adenoma, arising into the medial bronchopulmonary segment, lacking any relation to a bronchus.

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Alveolar adenoma: A rare lung tumor

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh0708461s ◽

2007 ◽

Vol 135 (7-8) ◽

pp. 461-464 ◽

Cited By ~ 2

Author(s):

Jelena Stojsic ◽

Branislava Milenkovic ◽

Jelena Radojicic ◽

Malina Percinkovski

Keyword(s):

Pulmonary Nodule ◽

Solitary Pulmonary Nodule ◽

Lung Tumor ◽

Fibrous Tissue ◽

Surgical Excision ◽

Middle Lobe ◽

Benign Lung Tumor ◽

Right Middle Lobe ◽

Malignant Alteration ◽

The Right

Introduction Alveolar adenoma belongs to the group of benign epithelial tumors. Histogenesis of alveolar adenoma is a combination of proliferation of alveolar pneumocytes and fibrous tissue originating from septal mesenchyma. Case outline A sixty-nine-year old female patient was hospitalized for clinical examination and surgery of well defined and homogenous timorous lesion in the right middle lobe causing pleural pain. Bronchoscopic examination with biopsy did not resolve etiology of the disease. Tumorectomy was performed. Timorous nodule had a multicystic appearance and histologically, histochemically and immunohistochemically, an alveolar adenoma was estimated. Five years after surgery, the patient feels well, without respiratory symptoms and signs of recurrence or malignant alteration, respectively. Conclusion Alveolar adenoma is a rare benign lung tumor, most frequently presented as a solitary pulmonary nodule. After complete surgery, the tumor neither relapses nor malignantly alters. Surgical excision is curative. It is necessary to take into consideration alveolar adenoma, too, when a solitary pulmonary nodule is diagnosed.

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Label Propagation Algorithm for the Slices Detection of a Ground-Glass Opacity Nodule

International Journal of Software Innovation ◽

10.4018/ijsi.2019010106 ◽

2019 ◽

Vol 7 (1) ◽

pp. 104-118 ◽

Cited By ~ 1

Author(s):

Weiwei Du ◽

Dandan Yuan ◽

Jianming Wang ◽

Xiaojie Duan ◽

Yanhe Ma ◽

...

Keyword(s):

Supervised Learning ◽

Lung Tumor ◽

Ground Glass Opacity ◽

Label Propagation ◽

Ground Glass ◽

Volume Data ◽

Propagation Algorithm ◽

Benign Lung Tumor ◽

The Impact ◽

Ct Volume

A radiologist must read hundreds of slices to recognize a malignant or benign lung tumor in computed tomography (CT) volume data. To reduce the burden of the radiologist, some proposals have been applied with the ground-glass opacity (GGO) nodules. However, the GGO nodules need be detected and labeled by a radiologist manually. Some slices with the GGO nodule can be missed because there are many slices in several volume data. Although some papers have proposed a semi-supervised learning method to find the slices with GGO nodules, the was no discussion on the impact of parameters in the proposed semi-supervised learning. This article also explains and analyzes the label propagation algorithm which is one of the semi-supervised learning methods to detect the slices including the GGO nodules based on the parameters. Experimental results show that the proposal can detect the slices including the GGO nodules effectively.

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Endobronchial Lipomatous Polyp: A Rare Benign Tumor of the Lung

Case Reports in Pulmonology ◽

10.1155/2014/240834 ◽

2014 ◽

Vol 2014 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Salim Surani ◽

Karen Allen ◽

Saherish Surani ◽

Joseph Varon

Keyword(s):

Benign Tumor ◽

Lung Tumor ◽

Benign Tumors ◽

Recurrent Pneumonia ◽

Benign Lung Tumor ◽

Rare Benign Tumor ◽

Endobronchial Lesion

Endobronchial lipomatous polyp is a rare nonmalignant tumor of the lung. It comprises 5% of the benign lung tumor, with the majority of benign tumors being hamartoma. Lipomatous polyp often leads to endobronchial lesion, associated with postobstructive pneumonia, hemoptysis, and atelectasis. We hereby present a case and discussion of an elderly man with endobronchial lipomatous polyp, presenting as recurrent pneumonia.

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A case of primary pulmonary synovial sarcoma initially diagnosed as a benign lung tumor due to calcification of the tumor

The Journal of the Japanese Association for Chest Surgery ◽

10.2995/jacsurg.28.488 ◽

2014 ◽

Vol 28 (4) ◽

pp. 488-494

Author(s):

Takeo Hasegawa ◽

Naoyuki Okabe ◽

Hiroshi Yaginuma ◽

Jun Ohsugi ◽

Mitsunori Higuchi ◽

...

Keyword(s):

Synovial Sarcoma ◽

Lung Tumor ◽

Benign Lung Tumor ◽

Primary Pulmonary Synovial Sarcoma

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Bronchial mucus gland hypertrophy: Its relation to symptoms and environment

British Journal of Diseases of the Chest ◽

10.1016/s0007-0971(66)80002-5 ◽

1966 ◽

Vol 60 (2) ◽

pp. 66-80 ◽

Cited By ~ 19

Author(s):

Winifred E.H. Field ◽

E.N. Davey ◽

Lynne Reid ◽

F.J.C. Roe

Keyword(s):

Bronchial Mucus ◽

Mucus Gland

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Surgical treatment for the patient with the neuroendocrine lung tumor associated with ectopic ACTH-secretion syndrome: case report

Endocrine Surgery ◽

10.14341/serg9766 ◽

2018 ◽

Vol 12 (2) ◽

pp. 96-101

Author(s):

Michail Y. Pikunov ◽

Alexey A. Pechetov ◽

Yury S. Esakov ◽

Alexey N. Lednev

Keyword(s):

Lung Tumor ◽

Clinical Manifestations ◽

Perioperative Period ◽

Carcinoid Tumors ◽

Long Term Results ◽

Optimal Method ◽

Ectopic Acth ◽

Ectopic Acth Secretion ◽

Results Of Treatment ◽

Topical Diagnosis

Among primary neoplasms of the lungs, the proportion of neuroendocrine tumors is up to 20–25%. According to the Surveillance Epidemiology and Results (SEER) database, since 1970 there has been a significant increase in primary carcinoid tumors of various organs with the highest incidence of morbidity in the broncho-pulmonary localization group. Carcinoid tumors of the lung level are approximately 2% of all primary lung tumors, but only 5% of these formations are associated with ACTH production. Despite the severity of clinical manifestations and the acceleration of hypercorticoid processes, the topical diagnosis of ACTH-ectopic syndrome often causes certain difficulties. The difficulty in diagnosing ectopic tumors is due to the fact that most of these formations are so small that they can be missed by standard methods of examination (X-ray, ultrasound, MSCT or MRI). After the diagnosis of ACTH-ectopic syndrome is completely optimal method of pathogenetic therapy is a radical removal of the tumor, which leads to the normalization of the functions of the adrenal cortex and the elimination of hypercorticoidism. However, the achievement of this goal in many cases is difficult due to late topical diagnosis, the prevalence of the tumor process and extensive metastasis. There is a clinical observation of a patient with a diagnosis of a neuroendocrine lung tumor with ACTH-ectopic syndrome. The importance of the multidisciplinary approach, the methods of differential diagnosis, the features of the perioperative period and the long-term results of treatment are described.

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A Fifteen Years’ Experience in the Diagnosis and Treatment of Benign Lung Tumors

Tumori Journal ◽

10.1177/030089168607200413 ◽

1986 ◽

Vol 72 (4) ◽

pp. 413-416

Author(s):

Cosimo Lequaglie ◽

Ferdinando Preda ◽

Mauro Ongari ◽

Marco Alloisio ◽

Gianluigi Ravasi

Keyword(s):

Lung Cancer ◽

Needle Biopsy ◽

Lung Tumor ◽

Primary Lung Cancer ◽

Clinical History ◽

Fine Needle Biopsy ◽

Lung Tumors ◽

Benign Lung Tumor ◽

Psychologic Stress ◽

Bronchial Washing

Even the most sophisticated examinations, such as computerized tomography and percutaneous fine needle biopsy, often do not allow a certain preoperative diagnosis of benign lung cancer. The clinical history may also be deceiving: a smoker over 35 years of age need not necessarily have a primary lung cancer, but this event is frequent enough to justify a diagnostic thoracotomy. In our series, chest tomography proved to be useful and sometimes revealed unsuspected lesions. In contrast, bronchoscopy is useful only for centrally located lesions, and the same is true for bronchial washing and brushing. Finally, thoracotomy, possibly an axillary one with enucleation or possibly transegmentary resection, is the most frequent operation in benign lung tumors, because of the unfailing diagnosis and for the minimal functional damage to the patient. A diagnostic thoracotomy may also avoid the psychologic stress suffered by a patient with a simple but undiagnosed benign lung tumor.

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Morphologic alteration in the muscles of patients with hypokalemic periodic paralysis or myopathy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100158650 ◽

1990 ◽

Vol 48 (3) ◽

pp. 222-223

Author(s):

T. Shimizu ◽

Y. Muranaka ◽

I. Ohta ◽

N. Honda

Keyword(s):

Clinical Manifestations ◽

Quadriceps Muscle ◽

Honeycomb Structure ◽

Periodic Paralysis ◽

Ultrastructural Changes ◽

Hypokalemic Periodic Paralysis ◽

Electron Microscopic ◽

Tubular Aggregates ◽

Hypokalemic Myopathy ◽

Transmission Electron

There have been many reports on ultrastructural alterations in muscles of hypokalemic periodic paralysis (hpp) and hypokalemic myopathy(hm). It is stressed in those reports that tubular structures such as tubular aggregates are usually to be found in hpp as a characteristic feature, but not in hm. We analyzed the histological differences between hpp and hm, comparing their clinical manifestations and morphologic changes in muscles. Materials analyzed were biopsied muscles from 18 patients which showed muscular symptoms due to hypokalemia. The muscle specimens were obtained by means of biopsy from quadriceps muscle and fixed with 2% glutaraldehyde (pH 7.4) and analyzed by ordinary method and modified Golgimethod. The ultrathin section were examined in JEOL 200CX transmission electron microscopy.Electron microscopic examinations disclosed dilated t-system and terminal cistern of sarcoplasmic reticulum (SR)(Fig 1), and an unique structure like “sixad” was occasionally observed in some specimens (Fig 2). Tubular aggregates (Fig 3) and honeycomb structure (Fig 4) were also common characteristic structures in all cases. These ultrastructural changes were common in both the hypokalemic periodic paralysis and the hypokalemic myopathy, regardless of the time of biopsy or the duration of hypokalemia suffered.

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