Hammering home the sickle: an instructive case of endobronchial anaplastic large cell lymphoma

It is extremely unusual for primary pulmonary lymphoma, an uncommon occurrence in any form, to be of T-cell origin and to manifest as an endobronchial lesion. Each of these characteristics is rare individually, so cases that combine them are exceptional. We report a patient in whom primary pulmonary anaplastic large cell lymphoma, a T-cell neoplasm, presented with obstruction of the left upper lobe bronchus, resulting in left upper lobe atelectasis and creating the radiographic luftsichel sign. We briefly discuss anaplastic large cell lymphoma as a whole, place our case in the context of previously published literature on endobronchial anaplastic large cell lymphoma, and review the genesis of the luftsichel sign.

Endobronchial Hamartoma with Postobstructive Pneumonia- A Case of Successful Treatment with Endobronchial Interventions

Airway hamartomas are of mesenchymal tissue origin and have predominance of adipose tissue. Hamartoma refers to a tumour-like structure within an organ composed of an abnormal arrangement of tissue components normally found in that organ. The pulmonary parenchyma and airways are commonly described sites for this lesion, although endobronchial location is far less common than its parenchymal counterpart. When present within a major airway, the usual symptoms of an airway lesion like cough, wheezing, stridor, haemoptysis and postobstructive consolidation ensue. We describe the case of a 60-year-old gentleman who presented with cough of 9 months duration. On evaluation he was found to have an endobronchial lesion in the right main bronchus. The histopathology revealed features of endobronchial hamartoma which was then subjected to endobronchial intervention with electrocautery and cryoablation achieving complete removal and restoration of luminal patency. This case underscores the ability of endobronchial treatment modalities to successfully treat benign airway lesions like hamartoma when undertaken in experienced centres.

Robotic Resection of Pulmonary Epithelial Myoepithelial Carcinoma: A Case Report

Background Pulmonary epithelial–myoepithelial carcinoma (P-EMC) is an extremely rare, well-differentiated, and malignant neoplasm originating from submucosal bronchial glands in the lung. EMCs arise mainly in the salivary glands. Case Description This case represents an asymptomatic 78-year-old male with a remote 75-pack-year history of smoking who presents with a solitary endobronchial lesion, which is suggestive of a primary lung EMC, detected on annual screening chest computed tomography (CT) scan. Conclusion A recent review of literature reveals less than 50 documented cases of the pulmonary subtype of this tumor worldwide. We are reporting a unique case of robot-assisted pulmonary lobectomy for a P-EMC.

Rare broncho-pulmonary arterial fistula in a healthy 9-year-old girl

A 9-year-old previously well girl presented with multiple episodes of large volume haemoptysis and right sided consolidation. She continued to have haemoptysis despite intravenous antibiotics. CT chest suggested a right mainstem endobronchial lesion; this was not seen on bronchoscopy where an extensive blood clot was removed. Distal flexible bronchoscopy could not identify the source of bleeding. CT angiogram revealed a broncho-pulmonary arterial fistula, a rare cause of haemoptysis in children. Endovascular embolisation resulted in short-term symptom resolution; however, haemoptysis recurred months later, leading to re-embolisation. This case highlights a stepwise approach to the workup of large volume haemoptysis.

Invasive Thymoma with Right Upper Lobe Endobronchial Lesion and Autoimmune Enteropathy

Thymomas are slow-growing neoplasia arising from the epithelial cells of the thymus that usually present with respiratory symptoms, superior vena cava syndrome, or parathymic syndromes. Approximately 30% of thymomas develop myasthenia gravis. An additional 5% of patients with thymomas have other systemic syndromes, including rheumatoid arthritis, thyroiditis, red cell aplasia, systemic lupus erythematosus, and Cushing syndrome. Rarely, patients can present with diarrhea due to thymoma-associated autoimmune gastrointestinal pathologies that include Good syndrome (acquired hypogammaglobulinemia), thymoma- associated multiorgan autoimmunity, and autoimmune enteropathy. We present an uncommon and interesting case of an invasive metastatic thymoma with right upper lobe endobronchial lesion and autoimmune enteropathy in a 27-year-old female. The novelty of this case lay in the findings of extensive metastatic thymoma with right upper lobe endobronchial disease and autoimmune diarrhea.