scholarly journals The Role of Magnetic Nanoparticles in the Localization and Treatment of Breast Cancer

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
M. Ahmed ◽  
M. Douek
Keyword(s):  
Breast Cancer ◽  
Magnetic Nanoparticles ◽  
Drug Delivery Systems ◽  
Magnetic Hyperthermia ◽  
Lymph Node Biopsy ◽  
Clinical Applications ◽  
Current Evidence ◽  
Oncological Surgery ◽  
Node Biopsy

The role of magnetic nanoparticles (MNPs) in medical applications is rapidly developing. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are challenging the traditional distinction between diagnostic and treatment agents. The current use of MNPs in breast cancer falls into four main groups: (1) imaging of primary and metastatic disease, (2) sentinel lymph node biopsy (SLNB), (3) drug delivery systems, and (4) magnetic hyperthermia. The current evidence for the use of MNPs in these fields is mounting, and potential cutting-edge clinical applications, particularly with relevance to the fields of breast oncological surgery, are emerging.

67P The role of FDG PET/CT to omit sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer

2021 ◽  
Vol 32 ◽  
pp. S50
Author(s):  
E. Tanrikulu Simsek ◽  
E. Çoban ◽  
E. Atag ◽  
S. Gungor ◽  
M. Sarı ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Neoadjuvant Chemotherapy ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Pet Ct ◽  
Fdg Pet Ct

Sentinel node biopsy in patients with microinvasive breast cancer: A systematic review and meta-analysis.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 1119-1119
Author(s):  
Helene Gojon ◽  
David Fawunmi ◽  
Antonis Valachis
Keyword(s):  
Breast Cancer ◽  
Sentinel Node ◽  
Meta Analysis ◽  
Lymph Node Biopsy ◽  
Eligibility Criteria ◽  
Summary Estimate ◽  
Node Biopsy ◽  
Study Heterogeneity ◽  
Microinvasive Breast Cancer

1119 Background: The aim of this meta-analysis is to evaluate the role of sentinel lymph node biopsy (SLNB) in patients with microinvasive breast cancer. Methods: We searched MEDLINE and ISI Web of Science to identify studies including patients with microinvasive breast cancer who underwent SLNB and reported the rate of sentinel-node positivity. We performed proportion meta-analysis using either fixed or random-effects model based on the between-study heterogeneity. Results: A total of 23 studies including 952 patients met the eligibility criteria. The summary estimate for the sentinel-node (SN) positivity rate was 3.1% (95% Confidence Interval (CI): 2.0%-4.4%), 4.1 % (95% CI 2.8%-5.6%), and 2.8% (95% CI : 1.6%-4.5%) for macrometastasis, micrometastasis and isolated tumor cells (ITC) respectively. Significant between-study heterogeneity was observed only in the meta-analysis of ITC positivity rate. Conclusions: The amount of positive sentinel node in patients with proven microinvasive breast cancer is relatively low. As a result, the indications for SLNB in these patients should be probably individualized.

scholarly journals The Ever-Changing Role of Sentinel Lymph Node Biopsy in the Management of Breast Cancer

2014 ◽  
Vol 138 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Steven Goodman ◽  
Ashling O'Connor ◽  
Dina Kandil ◽  
Ashraf Khan
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Sentinel Node ◽  
Lymph Node Biopsy ◽  
Axillary Lymph ◽  
Node Dissection ◽  
Node Biopsy

Context.—Axillary nodal status remains one of the most important prognostic indicators in the management of breast cancer. Axillary node metastases are seen in fewer than half of breast cancer cases, and axillary lymph node dissection is associated with significant morbidity. Sentinel lymph node biopsy (SLNB) has become the gold standard for axillary staging of breast cancer. Objective.—To present a detailed review of the existing studies on SLNB in relation to the various techniques, the pathologic evaluation of the sentinel node, and special situations that can involve SLNB. We discuss recent trials that have already had an influence on surgical and pathologic management of breast cancer. In this article, we also discuss our practice and experience at UMass Memorial Medical Center, Worcester, Massachusetts, from a pathologic and surgical perspective. Data Sources.—Published articles from peer-reviewed journals in PubMed (US National Library of Medicine). Conclusions.—Sentinel node biopsy has become standard of care in the surgical management of breast cancer, and emerging data show that the survival benefits of axillary lymph node dissection may not be greater than sentinel node biopsy alone in patients with up to 2 positive sentinel nodes. Therefore, there have been recent changes to the role of intraoperative sentinel node evaluation, and an impact on overall breast cancer management.

scholarly journals The Role of Sentinel Lymph Node Biopsy in Patients With B5c Breast Cancer Diagnosis

In Vivo ◽  
2019 ◽  
Vol 34 (1) ◽  
pp. 355-359
Author(s):  
PIERO FREGATTI ◽  
MARCO GIPPONI ◽  
RAQUEL DIAZ ◽  
RAFFAELE DE ROSA ◽  
FEDERICA MURELLI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Lymph Node Biopsy ◽  
Node Biopsy

Sentinel lymph node biopsy in breast cancer: the role of micrometastasis

2015 ◽  
Vol 32 (2) ◽  
Author(s):  
David Pérez-Callejo ◽  
Fernando Franco ◽  
Beatriz Núñez ◽  
Carmen González-Lois ◽  
Blanca Cantos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Lymph Node Biopsy ◽  
Node Biopsy
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