scholarly journals Successful Treatment of Mediastinal Unicentric Castleman’s Disease Using Video-Assisted Thoracoscopic Surgery with Preoperative Embolization

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Yosuke Amano ◽  
Daiya Takai ◽  
Nobuya Ohishi ◽  
Aya Shinozaki-Ushiku ◽  
Masashi Fukayama ◽  
...  
Keyword(s):  
Thoracoscopic Surgery ◽  
Castleman’S Disease ◽  
Preoperative Embolization ◽  
Castleman's Disease ◽  
Tumor Vascularity ◽  
Mediastinal Tumors ◽  
Video Assisted ◽  
Vascular Type ◽  
Hyaline Vascular Type ◽  
Video Assisted Thoracoscopic Surgery

Unicentric Castleman’s disease is a rare, benign lymphoproliferative disorder that is curable with surgical resection. However, significant bleeding often occurs during surgery because of tumor hypervascularity. We herein present a case of hyaline-vascular-type mediastinal unicentric Castleman’s disease, successfully resected using video-assisted thoracoscopic surgery with preoperative embolization. In the present case, tumor hypervascularity and feeding vessels were revealed by computed tomography (CT), which led us to perform preoperative angiography and embolization to the tumor feeding arteries to reduce intraoperative bleeding. Castleman’s disease should be considered in the differential diagnosis of hypervascular mediastinal tumors. Tumor vascularity should be assessed prior to surgery, and preoperative embolization should be considered.

Video-assisted thoracoscopic surgery is a safe and effective method to treat intrathoracic unicentric Castleman’s disease

2019 ◽  
Author(s):  
Yan-qing Wang ◽  
Shan-qing Li ◽  
Feng Guo
Keyword(s):  
Thoracoscopic Surgery ◽  
Tumor Resection ◽  
Castleman’S Disease ◽  
Maximum Diameter ◽  
Invasive Technique ◽  
Castleman's Disease ◽  
Video Assisted ◽  
Vascular Type ◽  
Complete Surgical Excision ◽  
Video Assisted Thoracoscopic Surgery

Abstract Background: Castleman's disease (CD) is a rare non-clonal lymphadenopathy. Application of video-assisted thoracoscopic surgery (VATs) in intrathoracic unicentric Castleman's disease (UCD) is rarely reported. This study is aimed to clarify the role of VATs for diagnosis and treatment in intrathoracic UCD. Methods: The authors reviewed and identified patients who had received a histologic diagnosis of CD through VATs at our hospital from January2010 to June 2018. Clinical and radiologic variables, histopathology, type of approach, complications, and long-term effect were analyzed to evaluate the safety and efficacy of VATs. Results: A total of 10 patients were included in this study, with 8 hyaline vascular type and 2 plasma cell type. The mean maximum diameter of the lesions was 4.66cm. Nine cases underwent complete surgical excision by VATs, and 1 case was converted to thoracotomy. All patients had no postoperative complications. With a median follow-up of 5 years (range: 1-9 years), no tumor recurrence was found in 9 patients receiving complete tumor resection, and 1 patient with incomplete tumor resection remained symptom free without clinical or radiographic progression. Conclusions: VATs is an acceptable, minimally invasive technique which results in excellent rates of cure in patients with intrathoracic UCD.

scholarly journals Unicentric Castleman’s Disease in a Man Originally Diagnosed with Sarcoidosis: A Case and Analysis of the Key Differences in Diagnosis

2019 ◽  
Vol 4 (4) ◽  
Keyword(s):  
Lymph Nodes ◽  
Surgical Resection ◽  
Lymphoproliferative Disorder ◽  
Castleman’S Disease ◽  
Castleman Disease ◽  
Castleman's Disease ◽  
Vascular Type ◽  
Hyaline Vascular Type ◽  
Complete Surgical Resection ◽  
Vascular Proliferation

Castleman Disease (CD) is a lymphoproliferative disorder characterized by enlarged hyperplastic lymph nodes with regressed follicles surrounded by expanded mantle zones of small lymphocytes, and interfollicular vascular proliferation in the hyaline-vascular type. There are two types: unicentric and multicentric. Unicentric, hyalinevascular type of Castleman’s disease can be treated successfully with complete surgical resection with monitoring for reoccurrence. Here we report a case of a patient originally diagnosed with sarcoidosis who was found to have Unicentric Castleman’s disease.

scholarly journals Castleman’s disease: an entity forgotten in ENT

2021 ◽  
Vol 7 (5) ◽  
pp. 905
Author(s):  
Mohamed Riyas Ali ◽  
Vikram Wadhwa ◽  
Ravi Meher ◽  
Reena Tomar ◽  
Karishma Singh ◽  
...  
Keyword(s):  
Castleman’S Disease ◽  
Treatment Modalities ◽  
Retropharyngeal Space ◽  
Castleman's Disease ◽  
Complete Excision ◽  
Vascular Type ◽  
Hyaline Vascular Type ◽  
Systemic Lymphadenopathy ◽  
Rare Site ◽  
Usual Site

<p class="abstract">Castleman’s disease (CD) usually presents as localized or systemic lymphadenopathy or as an extra nodal mass. The usual site of presentation are mediastinum, retroperitoneum, axilla and mesentery. Only 3 cases of CD have been reported in retro pharyngeal space. We report a case of 20 year old male patient with retropharyngeal mass. He presented with difficulty in swallowing, change in voice and respiratory distress. The mass was removed in-toto transorally after performing elective tracheostomy. The histopathological findings were consistent with hyaline vascular type of CD. He was decannulated after two day and postoperative period was uneventful. Postoperative CT imaging confirmed the complete excision of tumor and patient is on follow up, with no signs of recurrence. The presentation of tumour in the retropharyngeal space which is a rare site of occurrence add to the uniqueness of this case. Unicentric CD has an excellent prognosis and surgery is the management of choice. Its clinical features, histological subtypes, treatment modalities and prognosis are discussed.</p>

scholarly journals Retroperitoneal pararenal castleman’s disease: a case report

2013 ◽  
Vol 3 (6) ◽  
pp. 509-511
Author(s):  
S Shrestha ◽  
U Nepal ◽  
N Lamichhane ◽  
P Chhetri
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Castleman’S Disease ◽  
Accurate Diagnosis ◽  
Renal Tumors ◽  
Unknown Etiology ◽  
Resected Specimen ◽  
Castleman's Disease ◽  
Vascular Type ◽  
Hyaline Vascular Type

Castleman’s diseas is a rare lymphoproliferative disorder of unknown etiology. We report a 28 years old woman with solitary Castleman’s disease in the left pararenal space. This case was diagnosed preoperatively as renal cell carcinoma. The patient underwent a radical nephrectomy with dissection of pararenal mass. Histopathological examination of the surgically resected specimen showed the hyaline vascular type of Castleman’s disease. A preoperative diagnosis of Castleman’s disease is difficult; therefore, a surgical resection and histopathological evaluation can provide an accurate diagnosis of tumor. Taking this case into consideration, we suggest that Castleman’s disease should be included in the differential diagnosis of renal tumors. DOI: http://dx.doi.org/10.3126/jpn.v3i6.9004 Journal of Pathology of Nepal (2013) Vol. 3, 509-511

Rare case of the hyaline vascular type of Castleman's disease of the kidney

2007 ◽  
Vol 14 (12) ◽  
pp. 1098-1100 ◽  
Author(s):  
Koji. Hatano ◽  
Shigeki Fujita ◽  
Yuichi Tsujimoto ◽  
Tsuyoshi Takada ◽  
Masato Honda ◽  
...  
Keyword(s):  
Rare Case ◽  
Castleman’S Disease ◽  
Castleman's Disease ◽  
Vascular Type ◽  
Hyaline Vascular Type

scholarly journals “Follicular Variant” of Hyaline-vascular Type of Castleman's Disease : Histopathological and Immunohistochemical Study of 11 Cases

2008 ◽  
Vol 48 (2) ◽  
pp. 39-45 ◽  
Author(s):  
Masaru Kojima ◽  
Kazuhiko Shimizu ◽  
Hayato Ikota ◽  
Yoshihiro Ohno ◽  
Tadashi Motoori ◽  
...  
Keyword(s):  
Immunohistochemical Study ◽  
Castleman’S Disease ◽  
Castleman's Disease ◽  
Follicular Variant ◽  
Vascular Type ◽  
Hyaline Vascular Type
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