scholarly journals Validation of Antimycobacterial Plants Used by Traditional Healers in Three Districts of the Limpopo Province (South Africa)

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Peter Masoko ◽  
Kulani Mashudu Nxumalo

The aim of the study was to scientifically evaluate the antimycobacterial activity of selected indigenous medicinal plants from the Limpopo Province used for the treatment of humans with symptoms ofMycobacterium tuberculosis. The leaves of five plant species (Apodytes dimidiata, Artemisia, Combretum hereroense, Lippia javanica, and Zanthoxylum capense) were collected from the Lowveld National Botanical Garden in Nelspruit, South Africa. The dried leaves were powdered and extracted using hexane, dichloromethane, acetone, and methanol. Antimycobacterial activity was evaluated using microdilution assay and bioautography andρ-iodonitrotetrazolium violet (INT) as indicator. Antioxidant activities were determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH). Phytochemical content of extracts was further evaluated. The acetone extracts ofL. javanicadisplayed antioxidant activity on BEA chromatogram. T Acetone extracts ofA. afrahad MIC value of 0.39 mg/mL againstMycobacterium smegmatisATCC 1441. Acetone extracts ofC. hereroenseandL. javanicahad MIC value of 0.47 mg/mL. Four bands that inhibited the growth ofM. smegmatiswere observed atRfvalues of 0.12, 0.63, and 0.87 on BEA and 0.73 on EMW. The plant speciesA. dimidiata, A. afra, C. hereroense,andL. javanicain this study demonstrated their potential as sources of anti-TB drug leads.

2015 ◽  
Vol 9 (3) ◽  
pp. 71-77 ◽  
Author(s):  
Johannes Christoffel Erasmus Lourens ◽  
Johannes Potgieter Marthienus ◽  
Silas Semenya Sebua

2018 ◽  
Vol 2018 ◽  
pp. 1-33 ◽  
Author(s):  
Sebua Silas Semenya ◽  
Alfred Maroyi

To the best of our knowledge there are presently no ethnobotanical surveys focusing on the utilisation of herbal remedies for asthma in South Africa. The present study is therefore an attempt to fill this gap in knowledge. A total of 140 Bapedi traditional healers (THs) practicing in the Capricorn, Sekhukhune, and Waterberg districts of the Limpopo Province (South Africa) were queried using semistructured questionnaires, supplemented by field observations during face-to-face interview. A total of 104 medicinal plant species (92 indigenous and 12 exotics) belonging to 92 genera, distributed across 54 botanical families, mostly the Asteraceae and Fabaceae (18.5%, for each) as well as Malvaceae (12.9%), were used as antiasthmatics and related symptoms by these THs. Most of the plants were trees and herbs (37.5%, for each), with root (57%), leaf (15.8%), and bark (7.5%), respectively, being the saliently used parts for preparation of remedies.Clerodendrum ternatum,Cryptocarya transvaalensis,Lasiosiphon caffer,Enicostema axillare,Mimusops obovata,Sclerocarya birrea, andStylochaeton natalensiswere widely used and valued by all THs across the surveyed districts. Furthermore, these taxa also scored both the highest use value and fidelity level indexes as asthma therapies. Overall, the larger number of species documented in the present study is recorded for the first time in literature as asthma and/or related symptoms remedies. Our study finding generally contributes towards an establishment of South African database of herbal therapies used traditionally against these conditions.


Scientifica ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Sebua Silas Semenya ◽  
Alfred Maroyi

Several communities in developing countries derive substantial part of their livelihood needs from alien plants cultivated and managed in home gardens. The aim of this study was to assess useful alien plant species cultivated and managed in home gardens of Limpopo province in South Africa. Semistructured interviews, personal observation, and guided walks with 300 participants between January 2015 and December 2016 were employed to obtain data on names of alien plants cultivated in home gardens and their use categories. A total of 101 plant species belonging to 44 families were recorded from the study area. More than half of the species (66.3%) belonged to 14 families, Fabaceae, Asteraceae, Rosaceae, Solanaceae, Lamiaceae, Anacardiaceae, Poaceae, Amaranthaceae, Apocynaceae, Brassicaceae, Cactaceae, Euphorbiaceae, Moraceae, and Myrtaceae. Twenty-six use categories of alien plants were identified in this study with the majority of species (75.2%) used for medicinal purposes, followed by ornamental (33.7%), edible fruits (24.8%), spices (16.8%), vegetables (16.8%), shade (11.9%), beverages (10.9%), construction materials (8.9%), firewood (7.9%), and hedge (7.9%). These findings corroborate the existing body of knowledge emphasizing the importance of plants grown and managed in home gardens to the livelihood needs of local communities.


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