scholarly journals Unusual Metastatic Patterns of Invasive Lobular Carcinoma of the Breast

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Justin D. Sobinsky ◽  
Thomas D. Willson ◽  
Francis J. Podbielski ◽  
Mark M. Connolly
Keyword(s):  
Breast Carcinoma ◽  
Invasive Lobular Carcinoma ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Muscularis Propria ◽  
Metastatic Breast ◽  
Radical Mastectomy ◽  
Metastatic Colon Cancer ◽  
Carcinoma Of The Breast ◽  
Metastatic Patterns

Invasive lobular carcinoma of the breast has similar patterns of metastatic disease when compared to invasive ductal carcinoma; however, lobular carcinoma metastasizes to unusual sites more frequently. We present a 65-year-old female with a history of invasive lobular breast carcinoma (T3N3M0) treated with modified radical mastectomy and aromatase-inhibitor therapy who underwent a surveillance PET scan, which showed possible sigmoid cancer. Colonoscopy with biopsy revealed a 3 cm sigmoid adenocarcinoma. The patient underwent a lower anterior resection. Pathology showed an ulcerated, invasive moderately differentiated adenocarcinoma extending into but not through the muscularis propria. However, six of seventeen paracolonic lymph nodes were positive for metastatic breast carcinoma (ER+/PR+), consistent with her lobular primary breast carcinoma; there was no evidence of metastatic colon cancer. This case highlights the unusual metastatic patterns of lobular carcinoma.

scholarly journals Isolated Uterine Metastasis of Invasive Ductal Carcinoma

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Deniz Arslan ◽  
Deniz Tural ◽  
Ali Murat Tatlı ◽  
Emre Akar ◽  
Mükremin Uysal ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Metastatic Breast ◽  
Radical Mastectomy ◽  
Total Abdominal Hysterectomy ◽  
Breast Disease ◽  
Pathological Examination ◽  
First Case

Introduction. Most common metastasis sites of breast cancer are the lungs, bones, liver, and brain, whereas uterine involvement by metastatic breast disease is rare. Metastatic carcinoma of the uterus usually originates from other genital sites, most commonly being from the ovaries. Invasive lobular carcinoma spreads to gynecologic organs more frequently than invasive ductal carcinoma.Case Report. A 57-year-old postmenopausal woman was diagnosed with breast carcinoma 2 years ago and modified radical mastectomy was performed. Pathological examination of tumor revealed invasive ductal carcinoma, stage IIIc. She presented with abdominal pain and distension. Diagnostic workup and gynecologic examination revealed lesions that caused diffuse thickening of the uterus wall. Endometrial sampling was performed for confirmation of the diagnosis. She underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Breast carcinoma metastases in endometrium and myometrium were confirmed histopathologically and immunohistochemically.Conclusion. We herein report the first case of isolated uterine patient who had invasive ductal carcinoma of breast.

Lymph-node metastases in invasive lobular carcinoma are different from those in ductal carcinoma of the breast

2011 ◽  
Vol 64 (11) ◽  
pp. 995-1000 ◽  
Author(s):  
B. Fernandez ◽  
E. C. Paish ◽  
A. R. Green ◽  
A. H. S. Lee ◽  
R. D. Macmillan ◽  
...  
Keyword(s):  
Lymph Node ◽  
Invasive Lobular Carcinoma ◽  
Lymph Node Metastases ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Carcinoma Of The Breast ◽  
Node Metastases

scholarly journals Biliary Dyskinesia as a Rare Presentation of Metastatic Breast Carcinoma of the Gallbladder: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
A. Markelov ◽  
H. Taheri ◽  
K. Vunnamadala ◽  
G. Ibrahim
Keyword(s):  
Breast Carcinoma ◽  
Invasive Lobular Carcinoma ◽  
Lobular Carcinoma ◽  
Metastatic Breast ◽  
Rare Presentation ◽  
Metastatic Breast Carcinoma ◽  
Carcinoma Metastasis ◽  
Invasive Lobular Breast Cancer ◽  
The Brain ◽  
Common Malignancy

Background. Breast carcinoma is the most common malignancy in women worldwide. It is most commonly associated with metastases to the liver, lung, bone, and the brain. Invasive lobular carcinoma is a less common pathology with slightly higher metastases to the upper gastrointestinal tract. Invasive lobular carcinoma metastasis to the gallbladder is extremely rare.Method. In this paper we are presenting a case of a 67-year-old female with metastases of invasive lobular breast cancer to the gallbladder six years after her therapy.Conclusion. This case clearly signifies the nature of the micrometastatic foci of the invasive lobular carcinoma even many years after a successful treatment.

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