scholarly journals Serological Diagnosis and Follow-Up of Human Cystic Echinococcosis: A New Hope for the Future?

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Raúl Manzano-Román ◽  
Carlos Sánchez-Ovejero ◽  
Ana Hernández-González ◽  
Adriano Casulli ◽  
Mar Siles-Lucas
Keyword(s):  
Recombinant Proteins ◽  
Cystic Echinococcosis ◽  
Molecular Techniques ◽  
Limited Attention ◽  
Evidence Based ◽  
Multiple Factors ◽  
Health Authorities ◽  
Positive Results ◽  
Human Cystic Echinococcosis

Cystic echinococcosis (CE) is an important helminthic zoonotic disease caused by theEchinococcus granulosuscomplex. In humans, CE is a chronic disease driven by the growth of echinococcal cysts in different organs. Prognosis of this disease depends on multiple factors, including location, number, size, and stage of the cysts, making CE a disease of complex management. CE is usually asymptomatic for years and attracts limited attention from funding organizations and health authorities. For this reason, only experts’ recommendations are available but no evidence-based conclusions have been drawn for CE clinical management. One of those pitfalls refers to the lack of evidence to support the use of serological tools for the diagnosis and follow-up of CE patients. In this respect, crude antigens are used to detect specific antibodies in patients, giving rise to false positive results. The advent of molecular techniques allowing the production of recombinant proteins has provided a number of candidate antigens that could overcome the problems associated with the use of crude parasite extracts in the serological assays. In this review, we present the last advances in this field, proposing the use of serology to support cyst stage-specific diagnosis and follow-up.

Ultrasonographic diagnosis and medical treatment of human cystic echinococcosis in asymptomatic school age carriers: 5 years of follow-up

Acta Tropica ◽  
2004 ◽  
Vol 91 (1) ◽  
pp. 5-13 ◽  
Author(s):  
Edmundo Larrieu ◽  
Mario Del Carpio ◽  
Juan C Salvitti ◽  
Carlos Mercapide ◽  
Jose Sustersic ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Cystic Echinococcosis ◽  
School Age ◽  
Ultrasonographic Diagnosis ◽  
Human Cystic Echinococcosis

Clinical forensic medicine in Eastern Denmark: Organisation and assessments

2020 ◽  
Vol 60 (2) ◽  
pp. 150-158 ◽  
Author(s):  
Lykke Schrøder Jakobsen ◽  
Christina Jacobsen ◽  
Niels Lynnerup ◽  
Jacob Steinmetz ◽  
Jytte Banner
Keyword(s):  
Forensic Medicine ◽  
Public Confidence ◽  
Evidence Based ◽  
Clinical Forensic Medicine ◽  
Police Investigation ◽  
Health Authorities ◽  
International Diversity ◽  
Set Up ◽  
National Practice

Internationally, clinical forensic medicine (CFM) is diverse in content and conduct, and forensic medical methods are not always evidence based. The first step towards evidence-based practice is to achieve a thorough knowledge of international diversity, which necessitates that CFM practitioners provide information about their national practice. This paper’s aim is to describe the organisation of CFM in Denmark, exemplified by the set-up in Eastern Denmark, and the types of assessments performed. In Denmark, forensic medicine is a board-certified specialty under the health authorities, with mandatory qualifications. The Danish Accreditation Fund accredits the Departments of Forensic Medicine as inspection bodies, according to an international European standard that is approved by Danish Standards. Mainly at police request, forensic doctors perform examinations of both victims and suspected perpetrators of perilous crimes. The examinations’ purposes are documentation and assessment of the findings and collection of biological evidence. The clinical forensic examinations do not include any treatment or medical follow-up. Thus, the forensic doctors must be neutral, objective and impartial. The clinical forensic examinations provide documentation of findings and conclusions not otherwise available for the police investigation and legal aftermath. Moreover, the accredited, standardised protocols ensure that the Departments of Forensic Medicine meet their obligations as inspection bodies, thus ensuring public confidence in the departments’ services.

scholarly journals The Italian registry of cystic echinococcosis (RIEC): the first prospective registry with a European future

2015 ◽  
Vol 20 (18) ◽  
Author(s):  
F Tamarozzi ◽  
P Rossi ◽  
F Galati ◽  
M Mariconti ◽  
G J Nicoletti ◽  
...  
Keyword(s):  
Cystic Echinococcosis ◽  
Public Health Policies ◽  
Health Authorities ◽  
Seventh Framework Programme ◽  
Reporting Systems ◽  
Unnecessary Procedures ◽  
Framework Programme Project ◽  
European Registry ◽  
Human Cystic Echinococcosis ◽  
Actual Prevalence

Cystic echinococcosis (CE), a worldwide zoonosis, is highly endemic in southern and eastern Europe. Its actual prevalence is unknown due to the lack of efficient reporting systems designed to take into account the particular features of the disease. Neglect of CE makes diagnosis and clinical management difficult outside referral centres, with inconsistencies in clinical practice and often unnecessary procedures carried out that have associated risks and costs. The Italian registry of CE (RIEC) is a prospective multicentre registry of CE patients seen from January 2012 in Italian health centres; data are voluntarily submitted to the registry. Its aims are to show the prevalence of CE in Italy, bring the importance of this infection to the attention of health authorities, encourage public health policies towards its control, and stimulate biological, epidemiological and clinical research on CE. From January 2012 to February 2014, a total 346 patients were enrolled in 11 centres, outnumbering national reports of many CE-endemic European countries. We discuss preliminary data and challenges of the RIEC, template for the European registry of CE, which has been implemented within the Seventh Framework Programme project HERACLES (Human cystic Echinococcosis ReseArch in CentraL and Eastern Societies) since September 2014.

Post-survey follow-up for human cystic echinococcosis in northwest China

Acta Tropica ◽  
2006 ◽  
Vol 98 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Yunhai Wang ◽  
Tiehan He ◽  
Xinian Wen ◽  
Tao Li ◽  
Arbudu Waili ◽  
...  
Keyword(s):  
Cystic Echinococcosis ◽  
Northwest China ◽  
Human Cystic Echinococcosis

What Does Evidence-Based Practice Mean to You? A Follow-Up Study Examining School-Based Speech-Language Pathologists' Perspectives on Evidence-Based Practice

2020 ◽  
Vol 29 (2) ◽  
pp. 688-704
Author(s):  
Katrina Fulcher-Rood ◽  
Anny Castilla-Earls ◽  
Jeff Higginbotham
Keyword(s):  
Clinical Practice ◽  
Research Evidence ◽  
Evidence Based Practice ◽  
Evidence Based ◽  
Clinical Expertise ◽  
Speech Language Pathologists ◽  
School Based ◽  
Research Findings ◽  
Ebp Implementation

Purpose The current investigation is a follow-up from a previous study examining child language diagnostic decision making in school-based speech-language pathologists (SLPs). The purpose of this study was to examine the SLPs' perspectives regarding the use of evidence-based practice (EBP) in their clinical work. Method Semistructured phone interviews were conducted with 25 school-based SLPs who previously participated in an earlier study by Fulcher-Rood et al. 2018). SLPs were asked questions regarding their definition of EBP, the value of research evidence, contexts in which they implement scientific literature in clinical practice, and the barriers to implementing EBP. Results SLPs' definitions of EBP differed from current definitions, in that SLPs only included the use of research findings. SLPs seem to discuss EBP as it relates to treatment and not assessment. Reported barriers to EBP implementation were insufficient time, limited funding, and restrictions from their employment setting. SLPs found it difficult to translate research findings to clinical practice. SLPs implemented external research evidence when they did not have enough clinical expertise regarding a specific client or when they needed scientific evidence to support a strategy they used. Conclusions SLPs appear to use EBP for specific reasons and not for every clinical decision they make. In addition, SLPs rely on EBP for treatment decisions and not for assessment decisions. Educational systems potentially present other challenges that need to be considered for EBP implementation. Considerations for implementation science and the research-to-practice gap are discussed.

Middle School Students with Exceptional Learning Needs Investigate the Use of Visuals for Learning Science

2012 ◽  
Vol 7 (1) ◽  
Author(s):  
Robin Ward McCartney ◽  
Donna Dugger Wadsworth
Keyword(s):  
Students With Disabilities ◽  
Learning Needs ◽  
Evidence Based ◽  
School Students ◽  
Construction Of Knowledge ◽  
Personal Perceptions ◽  
Is Theory ◽  
Visual Graphic ◽  
Enhanced Learning ◽  
Positive Results

A visual instructional tool that is theory-driven and supported by evidence-based research is used to support student learning and information-processing. The graphic organizer has enhanced learning in Science Education as well as Special Education, emphasizing the construction of knowledge with meaningful sequential relationships rather than memorizing isolated fragments of information. Students construct a visual schema that represents a system of interrelated concepts and icons created by the learner. This article provides a description of a qualitative application of how students with disabilities are able to represent their ideas by assimilating subject matter and their personal perceptions of content by drawing pictures connected to concepts within the visual graphic. Positive results were documented in this study.

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