Ectopic Oral Tonsillar Tissue: A Case Series with Bilateral and Solitary Presentations and a Review of the Literature

An ectopic tonsil is defined as tonsillar tissue that develops in areas outside of the four major tonsil groups: the palatine, lingual, pharyngeal, and tubal tonsils. The occurrence of tonsillar tissue in the oral cavity in ectopic locations, its prevalence, and its developmental mechanisms that belong to its formation remain unclear. In this report, we describe a rare case of bilateral symmetric ectopic oral tonsillar tissue located at the ventral surface of the tongue along with two solitary cases arising from the floor of the mouth. The role of immune system and its aberrant response leading to ectopic deposits desires further studies. As an ectopic tonsil may simulate a benign soft tissue tumor, this case series highlights the importance of this entity in our clinical differential diagnosis of oral soft tissue masses.

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Adipocyte-rich CTNNB1-mutated Intramuscular Gardner Fibroma Progressing to Desmoid Fibromatosis

Pediatric and Developmental Pathology ◽

10.1177/1093526620968807 ◽

2020 ◽

pp. 109352662096880

Author(s):

Andrea Bakker ◽

Jonathan C Slack ◽

Mara Caragea ◽

Kyle C Kurek ◽

Marie-Anne Bründler

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumor ◽

Soft Tissue Tumors ◽

Molecular Testing ◽

Tissue Mass ◽

Desmoid Fibromatosis ◽

Benign Soft Tissue Tumor ◽

First Time ◽

Generation Sequencing

Gardner fibroma (GF) is a benign soft-tissue tumor that is associated with Gardner syndrome and can progress to, or co-occur with, desmoid fibromatosis (DF). Herein, we report a unique case of an 11-year-old boy who presented with a rapidly growing soft-tissue mass after biopsy of a stable fat-rich lesion present in the calf muscles since infancy, with Magnetic resonance imaging findings suggesting an intramuscular adipocytic tumor. The resection showed GF and DF. DF arising from a preexisting GF (the so-called “GF-DF sequence”) is a well-documented phenomenon. Although immunohistochemistry was negative for nuclear β-catenin expression, a CTTNB1 S45F mutation, which has been associated with aggressive behavior in DF, was identified in both components using a next-generation sequencing-based molecular assay. This is the first time a mutation in CTNNB1 has been identified in GF and the GF–DF sequence, thus expanding our knowledge of the molecular pathogenesis of the GF–DF sequence and highlighting the role of molecular testing in pediatric soft-tissue tumors. The histologic findings of an adipocyte-rich intramuscular GF also are unique, expanding the morphological spectrum of GF and adding GF to the differential diagnosis of intramuscular lesions with an adipocytic component.

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Leiomyoma of the Foot and Ankle: A Case Series

Foot & Ankle Specialist ◽

10.1177/1938640016670243 ◽

2016 ◽

Vol 10 (3) ◽

pp. 270-273 ◽

Cited By ~ 3

Author(s):

Lauren K. Szolomayer ◽

Paul G. Talusan ◽

Wayne F. Chan ◽

Dieter M. Lindskog

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumor ◽

Soft Tissue Mass ◽

Case Series ◽

The Body ◽

Foot And Ankle ◽

Tissue Mass ◽

Benign Soft Tissue Tumor ◽

Subcutaneous Mass ◽

Patient Presentation

Leiomyoma is a benign soft-tissue tumor that can arise in any soft tissue; however, in the extremities, it is usually a subcutaneous mass. Masses in the foot and ankle in general are rare, and few reports in the literature describe leiomyoma in this region of the body. We present a series of 8 cases of leiomyoma of the foot and ankle, 4 of which are subclassified as angioleiomyomas. The characteristic patient presentation, imaging, and histological findings are presented here to increase awareness of this soft-tissue mass in the foot and ankle. Levels of Evidence: Level V

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Giant Posttraumatic Angiolipoma of the Forearm: A Case Report and Review of the Literature

Case Reports in Orthopedics ◽

10.1155/2021/4047777 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Athanasios Fotiadis ◽

Petros Ioannidis ◽

Ioannis Skandalos ◽

Stergios Papastergiou ◽

Aristeidis Vrettakos ◽

...

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumor ◽

Histological Evaluation ◽

Surgical Removal ◽

Vascular Proliferation ◽

Soft Tissue Masses ◽

Benign Soft Tissue Tumor ◽

General Surgeons ◽

Magnetic Resonance Imaging Mri ◽

The Right

Angiolipoma is a type of lipoma, a benign soft tissue tumor. It is distinguished by the excessive degree of vascular proliferation and the presence of mature adipocytes. It occurs commonly on the trunk and extremities. Angiolipomas larger than 4 cm are classified as “giant,” and due to their size, histological evaluation is necessary to exclude malignancy. We report a case of a male patient who suffered from a giant noninfiltrating intramuscular angiolipoma which formed after venipuncture in the antecubital fossa. Clinical examination showed a palpable painless soft mass. Computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated a giant angiolipoma on the right forearm. Surgical removal of the mass was performed, and the biopsy was negative for malignancy. To the best of our knowledge, this is the first report in the literature of posttraumatic intramuscular angiolipoma. Physicians and orthopedic/general surgeons should be aware of the possibility of soft tissue masses in a posttrauma situation.

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Infantile Fibrosarcoma Histologically Mimicking a Benign Soft-Tissue Tumor

Journal of Research in Orthopedic Science ◽

10.32598/jrosj.7.4.726.1 ◽

2020 ◽

Vol 7 (4) ◽

pp. 179-184

Author(s):

Sam Hajialiloo Sami ◽

◽

Farshad Zandrahimi ◽

Mohamadreza Heidarikhoo ◽

Mahsa Zahmatkesh ◽

...

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumor ◽

Vascular Lesion ◽

Diagnostic Challenge ◽

Soft Tissue Neoplasm ◽

Infantile Fibrosarcoma ◽

Inappropriate Treatment ◽

Benign Soft Tissue Tumor ◽

One Year

Infantile fibrosarcoma is a rare soft-tissue neoplasm, which may render a diagnostic challenge leading to misdiagnosis and consequently an inappropriate treatment of patients. This study reports a case of infantile fibrosarcoma that mimicked a hemangioma in an 11-month-old girl. As the lesion signal in the MRI was not consistent with the diagnosis of hemangiomas, we performed a core needle biopsy, which its result was consistent with the diagnosis of infantile fibrosarcoma. The lesion was initially treated with surgical resection. However, the lesion recurred one year after the surgery. The recurrence was managed with debulking surgery. The fifth finger was necrotized during the hospitalization after the relapse surgery. Finally, the necrotic finger was amputated. Also, adjuvant chemotherapy was used to prevent further relapses. The 1-year follow-up of the patient was recurrence-free. These findings highlight the importance of considering infantile fibrosarcoma when an infant presents with a lesion that clinically mimics a vascular lesion.

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The Role of Ultrasound in the Diagnosis of Soft Tissue Tumors

Seminars in Musculoskeletal Radiology ◽

10.1055/s-0039-3402060 ◽

2020 ◽

Vol 24 (02) ◽

pp. 135-155

Author(s):

Maria Pilar Aparisi Gómez ◽

Costantino Errani ◽

Radhesh Lalam ◽

Violeta Vasilevska Nikodinovska ◽

Stefano Fanti ◽

...

Keyword(s):

Soft Tissue ◽

Benign Lesion ◽

Soft Tissue Tumors ◽

Resonance Imaging ◽

Benign Lesions ◽

Tumor Center ◽

Soft Tissue Masses ◽

Magnetic Resonance Imaging Mri ◽

Superficial Soft Tissue

AbstractThe vast majority of soft tissue masses are benign. Benign lesions such as superficial lipomas and ganglia are by far the most common soft tissue masses and can be readily identified and excluded on ultrasound (US). US is an ideal triaging tool for superficial soft tissue masses. Compared with magnetic resonance imaging (MRI), High-resolution US is inexpensive, readily available, well tolerated, and safe. It also allows the radiologist to interact with the patient as a clinician. In this review, we describe and illustrate the lesions with typical (diagnostic) US features. When the appearances of the lesion are not typical as expected for a benign lesion, lesions are deep or large, or malignancy is suspected clinically, MRI and biopsy are needed. The management of suspicious soft tissue tumors has to be carefully planned by a multidisciplinary team involving specialized surgeons and pathologists at a tumor center.

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