scholarly journals Pediatric Granular Cell Tumor of the Breast: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Nathan P. Heinzerling ◽  
Shannon M. Koehler ◽  
Sara Szabo ◽  
Amy J. Wagner
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Excisional Biopsy ◽  
Cell Tumor ◽  
The Body ◽  
Positive Staining ◽  
Review Of The Literature ◽  
Rare Presentation ◽  
Breast Masses

Objective. Granular cell tumors arise from neurogenic mesenchymal stem cells and can occur anywhere throughout the body. They rarely present as breast masses and should be included in the differential diagnosis of pediatric breast neoplasms. We report a rare presentation of a pediatric breast granular cell tumor and a review of the literature.Participant. A 15-year-old female presented with an enlarging breast mass. She underwent ultrasound imaging and excisional biopsy, which revealed a granular cell tumor. Granular cell tumors of the breast are difficult to diagnose using ultrasound and mammography due to numerous similarities to other breast masses. Histopathologic staining best differentiates breast granular cell tumors from other breast masses with their positive staining for S100, CD68, and neurospecific enolase.Conclusion. Although rare, granular cell tumors of the breast should be considered as a possible diagnosis for pediatric breast masses to allow for proper management and follow-up for these patients. Although rare, these tumors do have malignant potential necessitating a correct and timely diagnosis.

scholarly journals An axillary granular cell tumor: A rare neoplasm at an unusual site

2021 ◽  
Vol 12 (2) ◽  
pp. 177-179
Author(s):  
Issam Msakni ◽  
Aya Khemir ◽  
Faten Gargouri
Keyword(s):  
Granular Cell Tumor ◽  
Invasive Carcinoma ◽  
Granular Cell ◽  
Cell Tumor ◽  
The Body ◽  
Unusual Site ◽  
Rare Neoplasm ◽  
Complete Surgical Resection ◽  
Subcutaneous Tissues

A granular cell tumor (GCT) is a rare neoplasm occurring usually in submucosal and subcutaneous tissues anywhere in the body, affecting mainly the head and neck. GCTs at unusual anatomic sites, such as the breast or the axillary extension, could be taken for invasive carcinoma. We report the case of a 30-year-old male who presented himself with an axillary nodule. A physical examination revealed a firm and painless subcutaneous tumor on ulcerated skin. Lymphoma and lymph node metastasis were suspected. An imaging survey was negative outside the axillary nodule. The tumor was surgically removed. A microscopic examination showed the typical features of a benign GCT. Surgical margins were negative. No recurrence has been observed within a 6-month follow-up period. A GCT can mimic a malignancy since it presents itself as an axillary nodule, and requires complete surgical resection with clear margins.

Granular Cell Tumor of the Breast: A Series of 17 Cases and Review of the Literature

2004 ◽  
Vol 10 (6) ◽  
pp. 528-531 ◽  
Author(s):  
Adebowale Adeniran ◽  
Hikmat Al-Ahmadie ◽  
Mary C. Mahoney ◽  
Toni M. Robinson-Smith
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature

scholarly journals Diagnosis and Treatment of Esophageal Granular Cell Tumor: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Ramin Niknam ◽  
Kamran Bagheri Lankarani ◽  
Bita Geramizadeh
Keyword(s):  
Case Report ◽  
Endoscopic Ultrasonography ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Endoscopic Technique ◽  
Diagnosis And Treatment ◽  
Review Of The Literature ◽  
Common Site

Gastrointestinal granular cell tumors are uncommon. The most common site of gastrointestinal granular cell tumor (GCT) is esophagus. We report a case of esophageal GCT incidentally diagnosed by endoscopy. The lesion was evaluated by endoscopic ultrasonography and resected using the endoscopic technique without complication.

Symptomatic Granular Cell Tumor of the Pituitary Gland: Case Report and Review of the Literature

Neurosurgery ◽  
1998 ◽  
Vol 42 (1) ◽  
pp. 166-170 ◽  
Author(s):  
Bernhard Schaller ◽  
Eberhard Kirsch ◽  
Markus Tolnay ◽  
Thomas Mindermann
Keyword(s):  
Case Report ◽  
Pituitary Gland ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature

Granular Cell Tumor of the Orbit: Case Report and Review of the Literature

1983 ◽  
Vol 14 (2) ◽  
pp. 125-129
Author(s):  
Zeynel A Karcioglu ◽  
Gregory L Hemphill ◽  
Brandon M Wool
Keyword(s):  
Case Report ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature

scholarly journals Colonic granular cell tumor: Report of 11�cases and management with review of the literature

2018 ◽  
Author(s):  
Yahua Chen ◽  
Yangyang Chen ◽  
Xiaoqiong Chen ◽  
Liang Chen ◽  
Wei Liang
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Review Of The Literature

Oral granular cell tumors: an analysis of 10 new pediatric and adolescent cases and a review of the literature

2005 ◽  
Vol 29 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Robert Brannon ◽  
Payal Anand
Keyword(s):  
English Language ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Soft Tissue Neoplasm ◽  
Adolescent Population ◽  
Male Ratio ◽  
Common Location

Clinicopathologic studies on the granular cell tumor, a submucosal benign soft-tissue neoplasm, have not addressed the pediatric and adolescent population. This study of patients from birth to 19 years of age describes clinically and microscopically 10 new cases and combines them with 24 well-documented pediatric cases previously published in the English-language literature. Of the 34, patient ages ranged from 3 to 19 years (mean age 14.5 years) with a female-to-male ratio of 3.3 to 1. The most common location was the tongue (50%) and lips (25%). In neoplasms whose epithelial findings were documented microscopically, a reactive pseudoepitheliomatous (pseudocarcinomatous) hyperplasia of the overlying epithelium occurred in 29%. The recurrence rate was less than 10% following conservative surgical excision. This study reveals that an oral granular cell tumor in the first decade of life is an uncommon event and discusses the importance of differentiating between squamous cell carcinoma and granular cell tumor.

scholarly journals Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Yara A. Alnashwan ◽  
Khaled A. H. Ali ◽  
Samir S. Amr
Keyword(s):  
Abdominal Wall ◽  
Poor Prognosis ◽  
Granular Cell Tumor ◽  
Anterior Abdominal Wall ◽  
Granular Cell ◽  
Cell Tumor ◽  
Prolonged Survival ◽  
Review Of The Literature ◽  
Malignant Granular Cell Tumor ◽  
The Right

Malignant granular cell tumor (MGCT) is a rare high-grade mesenchymal tumor of Schwann cell origin. MGCTs commonly affect thigh, extremity, and trunk; however, involvement of the abdominal wall is quite rare. It has poor prognosis with 39% mortality rate in 3-year interval. We report a 50-year-old female who had MGCT arising in the anterior abdominal wall and developed massive metastatic deposits in both lungs and in the right inguinal lymph nodes, with prolonged survival for 11 years. A brief review of the literature is presented.

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