scholarly journals Primary Small Cell Carcinoma of the Hypopharynx: A Case Report of a Rare Tumor

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Ali Bayram ◽  
Ebru Akay ◽  
Sema S. Göksu ◽  
İbrahim Özcan

Introduction. Primary hypopharynx involvement of small cell carcinoma is very rare and very few cases have been reported in the literature. Here, we report a case of primary small cell carcinoma of the hypopharynx in a male patient.Case Report. A 50-year-old man presented with a 6-month history of sore throat and swellings in the right side of the neck. Direct laryngoscopy and biopsy revealed small cell carcinoma of the hypopharynx located in the right pyriform sinus.Discussion. Small cell carcinoma of the hypopharynx has no clear treatment modality due to the rarity of the disease. Systemic chemotherapy and radiotherapy should have priority among the therapy regimens because of the high metastatic potential of the tumor.

Author(s):  
Nida Javed ◽  
Aun Jamal ◽  
Noor Mubeen ◽  
Anam Mumtaz ◽  
Sidra Afzal ◽  
...  

2016 ◽  
Vol 107 (1) ◽  
pp. 34-38
Author(s):  
Akihiro Naito ◽  
Akihiko Matsumoto ◽  
Keiko Odani ◽  
Yujiro Sato ◽  
Takeshi Azuma ◽  
...  

2014 ◽  
Vol 6 (3) ◽  
pp. 186-188
Author(s):  
M. Khmou ◽  
F. Zouaidia ◽  
H. Ouazzani ◽  
A. Jahid ◽  
K. Znati ◽  
...  

2018 ◽  
Vol 1 (1) ◽  
pp. 125-128
Author(s):  
Guermazi F ◽  
Meddeb K ◽  
Mokrani A ◽  
Charfi L ◽  
Abouda HS ◽  
...  

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT) is an exceedingly rare aggressive malignancy. It typically affects young women. Herein we aimed to report a case of a 28-year-old woman treated for SCCOHT in Salah Azaiez Institute. The tumor was revealed by a delay of menses. The imaging found a large mass of the right ovary. The patient underwent a bilateral salpingo-oophorectomy, a total hysterectomy and a pelvic and a para-aortic lymphadenectomy. She subsequently received 6 cycles of adjuvant chemotherapy. Three years later, she presented a metastatic bone relapse.


1986 ◽  
Vol 85 (1) ◽  
pp. 96-101 ◽  
Author(s):  
Yangja Jung-Legg ◽  
Stephen E. Mcgowan ◽  
Kristin G. Sweeney ◽  
Jeffrey L. Zitzman ◽  
Robert D. Pugatch

2017 ◽  
Vol 5 (1) ◽  
pp. 35-39
Author(s):  
Vanda Salutari ◽  
Patricia Pautier

Ovarian small cell carcinoma is a rare tumor associated with poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, there is no evidencebased consensus for a standard treatment, although in the majority of cases platinum-based regimens are used. A case of small cell carcinoma of the ovary, hypercalcemic-type (SCCOHT), in a 22 year-old patient is reported.


2010 ◽  
Vol 124 (11) ◽  
pp. 1223-1226 ◽  
Author(s):  
T Goto ◽  
N Bandoh ◽  
T Nagato ◽  
M Takahara ◽  
Y Harabuchi ◽  
...  

AbstractObjective:We present the first reported case of primary small cell carcinoma of the lacrimal sac.Case report:A 67-year-old Japanese woman was referred to our department with a two-month history of left medial canthal swelling, epiphora and occasional nasal bleeding. Nasal endoscopy revealed a readily bleeding tumour in the left inferior meatus. Computed tomography and magnetic resonance imaging scans demonstrated that the tumour was mainly located in the left lacrimal sac. Histopathological studies of a biopsy specimen revealed small cell carcinoma. The patient was treated with four cycles of chemotherapy consisting of cisplatin and etoposide, in combination with radiotherapy. There was no evidence of recurrence or metastasis for five years.Conclusion:Small cell carcinoma originating in the head and neck region has been reported to be highly aggressive and to have a poor prognosis. We report a case of primary small cell carcinoma of the lacrimal sac successfully treated with chemo-radiotherapy.


2021 ◽  
Vol 9 ◽  
pp. 232470962110087
Author(s):  
Komal Akhtar ◽  
Vrinda Vyas ◽  
Prashanth Ashok Kumar ◽  
James Corines ◽  
Gustavo de la Roza ◽  
...  

Neuroendocrine tumors (NETs) are a heterogeneous group of tumors developing from neural crest cells, with numerous sites of origin, commonly the gastrointestinal and genitourinary tracts. NETs of the genitourinary tract are more common in women. Small cell carcinoma of the prostate or testicular carcinoid are the NETs in male. In this article, we present a rare case of NET of the scrotum. Our patient was a 47-year-old male with a history of complicated pilonidal cysts resulting in chronic scrotal wounds. Biopsy of a large nonhealing scrotal wound revealed a high-grade neuroendocrine carcinoma with features most suggestive of small cell carcinoma. Presenting with advanced disease at diagnosis, he was started on systemic therapy and unfortunately progressed through multiple lines of treatment, including CAPTEM (capecitabine and temozolomide). Unfortunately, due to multiple logistical reasons, the patient was unable to receive the then off-label immunotherapy based on DART (Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors) trial. He, unfortunately, succumbed to his disease within months of diagnosis.


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