scholarly journals Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Nicholas T. Vozoris ◽  
Jane Batt
Keyword(s):  
United States ◽  
Hispanic Americans ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
The United States ◽  
Tuberculosis Infection ◽  
Vulnerable Groups ◽  
Interferon Gamma Release Assay ◽  
The Us ◽  
Ltbi Testing

Purpose. There is no information on the change in prevalence of latent tuberculosis infection (LTBI) testing in the United States (US) following the introduction of the interferon gamma release assay (IGRA), a new and alternative diagnostic method for LTBI. The purpose of this study was to evaluate potential changes in the prevalence of LTBI testing in the US following the introduction of IGRA.Methods. This was a multiyear cross-sectional study using nationally representative data from the 1999-2000 and 2011-2012 US National Health and Nutrition Examination Surveys. Self-reported prevalence of LTBI testing was estimated among groups known to have increased LTBI risk. Descriptive statistics were used.Results. Compared to 1999-2000, significantly fewer individuals self-reported being tested for LTBI in 2011-2012 among Hispanic Americans (68.0% versus 60.7%,p<0.0001) and among those with comorbidities (74.7% versus 72.0%,p=0.02). There were also nonsignificant trends towards less self-reported LTBI testing in 2011-2012 versus 1999-2000 among household contacts of active TB cases, foreign-born individuals, and African Americans.Conclusions. Despite the introduction of IGRA, LTBI testing occurs less frequently in the US among vulnerable groups. Possibly inadequate targeted LTBI testing could result in increased active TB in the US in the future.

scholarly journals Estimates of Testing for Latent Tuberculosis Infection and Cost, United States, 2013

2019 ◽  
Vol 134 (5) ◽  
pp. 522-527 ◽  
Author(s):  
Suzanne M. Marks ◽  
Rachel Yelk Woodruff ◽  
Kwame Owusu-Edusei ◽  
Garrett R. Beeler Asay ◽  
Andrew N. Hill
Keyword(s):  
United States ◽  
Public Sector ◽  
Private Sector ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
The United States ◽  
Biomedical Literature ◽  
Tuberculosis Infection ◽  
Skin Tests ◽  
Ltbi Testing

Objectives: Tracking trends in the testing of latent tuberculosis infection (LTBI) can help measure tuberculosis elimination efforts in the United States. The objectives of this study were to estimate (1) the annual number of persons tested for LTBI and the number of LTBI tests conducted, by type of test and by public, private, and military sectors, and (2) the cost of LTBI testing in the United States. Methods: We searched the biomedical literature for published data on private-sector and military LTBI testing in 2013, and we used back-calculation to estimate public-sector LTBI testing. To estimate costs, we applied Medicare-allowable reimbursements in 2013 by test type. Results: We estimated an average (low-high) 13.3 million (11.3-15.4 million) persons tested for LTBI and 15.3 million (12.9-17.7 million) LTBI tests, of which 13.2 million (11.1-15.3 million) were tuberculin skin tests and 2.1 million (1.8-2.4 million) were interferon-γ release assays (IGRAs). Eighty percent of persons tested were in the public sector, 18% were in the private sector, and 2% were in the military. Costs of LTBI tests and of chest radiography totaled $314 million (range, $256 million to $403 million). Conclusions: To achieve tuberculosis elimination, millions more persons will need to be tested in all sectors. By targeting testing to only those at high risk of tuberculosis and by using more specific IGRA tests, the incidence of tuberculosis in the United States can be reduced and resources can be more efficiently used.

The Prevalence of Latent Tuberculosis Infection in the United States

2016 ◽  
Vol 194 (4) ◽  
pp. 501-509 ◽  
Author(s):  
James D. Mancuso ◽  
Jeffrey M. Diffenderfer ◽  
Bijan J. Ghassemieh ◽  
David J. Horne ◽  
Tzu-Cheg Kao
Keyword(s):  
United States ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
The United States ◽  
Tuberculosis Infection

scholarly journals Association between vitamin D and latent tuberculosis infection in the United States: NHANES, 2011–2012

2019 ◽  
Vol Volume 12 ◽  
pp. 2251-2257 ◽  
Author(s):  
Cheng-Yi Wang ◽  
Yin-Lan Hu ◽  
Ya-Hui Wang ◽  
Cheng-Hsin Chen ◽  
Chih-Cheng Lai ◽  
...  
Keyword(s):  
United States ◽  
Vitamin D ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
The United States ◽  
Tuberculosis Infection

scholarly journals Modeling the Impact of Recommendations for Primary Care–Based Screening for Latent Tuberculosis Infection in California

2020 ◽  
Vol 135 (1_suppl) ◽  
pp. 172S-181S
Author(s):  
Andrea Parriott ◽  
James G. Kahn ◽  
Haleh Ashki ◽  
Adam Readhead ◽  
Pennan M. Barry ◽  
...  
Keyword(s):  
Primary Care ◽  
Latent Tuberculosis Infection ◽  
Task Force ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection ◽  
California Department ◽  
The Us ◽  
Almost All ◽  
The Impact ◽  
Ltbi Testing

Objective Targeted testing and treatment of persons with latent tuberculosis infection (LTBI) is a critical component of the US tuberculosis (TB) elimination strategy. In January 2016, the California Department of Public Health issued a tool and user guide for TB risk assessment (California tool) and guidance for LTBI testing, and in September 2016, the US Preventive Services Task Force (USPSTF) issued recommendations for LTBI testing in primary care settings. We estimated the epidemiologic effect of adherence to both recommendations in California. Methods We used an individual-based Markov micro-simulation model to estimate the number of cases of TB disease expected through 2026 with baseline LTBI strategies compared with implementation of the USPSTF or California tool guidance. We estimated the risk of LTBI by age and country of origin, the probability of being in a targeted population, and the probability of presenting for primary care based on available data. We assumed 100% adherence to testing guidance but imperfect adherence to treatment. Results Implementation of USPSTF and California tool guidance would result in nearly identical numbers of tests administered and cases of TB disease prevented. Perfect adherence to either recommendation would result in approximately 7000 cases of TB disease averted (40% reduction compared with baseline) by 2026. Almost all of this decline would be driven by a reduction in the number of cases among non–US-born persons. Conclusions By focusing on the non–US-born population, adherence to LTBI testing strategies recommended by the USPSTF and the California tool could substantially reduce the burden of TB disease in California in the next decade.

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