scholarly journals Haemodialysis in the Octogenarian: More Than a Decade of Experience from a Single UK Centre

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Philip Thomas ◽  
Anna Price ◽  
Jyoti Baharani

Background. To assess factors affecting survival in an octogenarian cohort commencing haemodialysis (HD) and describe outcomes associated with prolonged survival. Materials and Methods. We retrospectively analysed 11 years of data (1 January 2000–31 December 2010) from patients aged ≥ 80 years starting HD at a teaching hospital in the United Kingdom. Data was collected on patient demographics, aetiology of renal failure, indication and duration of HD, access type at first dialysis, Charlson comorbidity index score, and cause of death. Results. Data from 139 eligible patients was included for analysis (85 male, 54 female (1.54 : 1)). The mean age was 83.6±2.8 years and 90% of this cohort were Caucasian. Thirty percent (42/139) of the cohort died within 90 days of starting dialysis. For those who survived >90 days the mean (median) duration of HD was 871.8 (805) days. Long-term survival was more common in females and those who first dialysed through an AVF. Conclusions. There is a significant early mortality risk in octogenarians commencing HD. For individuals who survive beyond the initial 90 days, the majority have a good long-term survival and our results are better than previously published UK data. Long-term survival was more common in female patients and those starting HD using an AVF.

Author(s):  
Seong Kyeong Lim ◽  
Kyoungwon Jung ◽  
Moo In Park ◽  
Jae Hyun Kim ◽  
Sung Eun Kim ◽  
...  

2020 ◽  
pp. 1-2
Author(s):  
Yi-Qian ZHU ◽  
CHEN Bao-An ◽  
Cheng Jian ◽  
Yi-Qian ZHU

Acute myeloid leukemia (AML) is a common malignancy of the blood system, and most patients are so ill that they often die if they are untreated in time. In recent years, with the improvement of chemotherapy drugs and methods, the complete remission rate has been significantly improved, but the long-term survival rate still has great room for improvement. This review summarized the influencing factors related to the long-term survival of AML patients through reading and sorting out multiple pieces of literature.


Author(s):  
Iaroslav P. Truba ◽  
Ivan V. Dziuryi ◽  
Roman I. Sekelyk ◽  
Oleksandr S. Golovenko

The problem of the effectiveness of obstruction at the level of the aortic arch is still a matter of discus-sion in the modern literature. Traditionally, by excision of the coarctation part, in the presence of hypoplasia, the incision is extended to a narrowed area and a modification of the classical end-to-end anastomosis is applied in the form of an elongated or expanded variant. Recently, when proximal part is involved in the pathological process, cardiac surgeons have been more likely to use median sternotomy using other types of plastic surgery, including dilation of the narrowed area with a pericardial patch, or pulmonary artery tissue. Accordingly, the analysis of the results of the use of end-to-end anastomosis in young children with aortic arch hypoplasia, especially in view of long-term survival and the level of reoperation, is an important issue of neonatal cardiac surgery. The aim. To evaluate the effectiveness of the use of an extended end-to-end anastomosis after reconstruction of the aortic arch in children under 1 year of age. Materials and methods. The study material included 348 infants who underwent surgical correction of aortic arch hypoplasia through the method of extended end-to-end anastomosis from 2010 to 2020. The operations were performed at the National Amosov Institute of Cardiovascular Surgery of the NAMS of Ukraine and the Ukrainian Children’s Cardiac Center. The study group included only patients with two-ventricular physiology. There were 233 male patients (67%) and 115 female patients (33%). The mean age was 1.07 (0.20; 2.30) months, the mean weight was 3.89 (3.30; 4.90) kg, the mean body surface area was 0.23 (0.20; 0.28) m2. Diagnosis of aortic arch hypoplasia was based on two-dimensional echocardiography. Results. According to echocardiography, after surgery there was a significant decrease in the pressure gradient in the aortic arch from 48.3 ± 20.3 to 16 ± 6.9 (p<0.05), left ventricular PV increased significantly from 61.6 ± 12% to 66.3 ± 6.4% (p> 0.05). The hospital mortality was 1.7% (n = 6). The causes of mortality were not related to the end-to-end aortic arch technique. The duration of follow-up period ranged from 1 month to 9.3 years. Two deaths occurred in the follow-up period. Thirty-two (9.1%) patients developed aortic arch restenosis in the postoperative period. Balloon dilatation of restenosis was performed in 21 patients. Eleven patients underwent repeated aortic arch repair surgery through the median sternotomy. There were no central nervous system complications in the follow-up period. Conclusions. The use of an extended end-to-end anastomosis in the surgical treatment of aortic arch hypoplasia demon strates low hospital mortality and high long-term survival. Indications for the effective use of this type of reconstruction are hypoplasia of the isthmus and distal aortic arch.


2020 ◽  
Vol 33 (Supplement_1) ◽  
Author(s):  
T Nishimura

Abstract   Gastroesophageal varices are present in approximately 50% of patients with cirrhosis, and their rupture is a life-threatening complication. However, mortality rates have declined due to the progress in the management of these patients. Especially advances in endoscopic treatment have contributed to the improved survival rates. In this study, we investigated the prognostic factors associated with long-term survival after endoscopic treatment for esophageal varices. Methods The subjects were 260 patients who underwent initial endoscopic treatment for esophageal varices in our hospital between January 1997 and June 2019. Among them, 160 successfully followed up. The patients’ characteristics were: mean age, 65.4 years (29–85); 109 men and 51 women; and median survival period, 53 months. For analysis, subjects were divided into long-term survival and non-long-term survival groups (n = 59 for each) with a 53-month survival period as a cut-off value. Results The long-term/non-long-term survival group had a preoperative Child-Pugh score of 6.2 ± 1.1/7.4 ± 2.0 (p &lt; 0.01) and hepatocellular carcinoma (HCC) presence rate was 25.4%/55.9% (p &lt; 0.01), significantly higher in the non-long-term group. Analysis of the factors affecting survival period using Cox proportional hazards model showed that Child-Pugh score B or C [hazard ratio(HR):2.0143, p &lt; 0.05], total bilirubin value≧ 2 [HR:2.5573, p &lt; 0.05], and presence of HCC [HR:2.2450, p &lt; 0.01] were noted as significant factors. Only presence of HCC was found to be a significant factor affecting the long-term survival using multiple logistic regression analysis [odds ratio:0.3463, p &lt; 0.05]. Conclusion Our study revealed that liver function and the presence of HCC affect long-term prognosis after endoscopic treatment for esophageal varices.


2001 ◽  
Vol 34 ◽  
pp. 216 ◽  
Author(s):  
M.I. Prince ◽  
A. Chetwynd ◽  
P.J. Diggle ◽  
J.V. Metcalf ◽  
O.F. James

2007 ◽  
Vol 69 (7) ◽  
pp. 1037-1043 ◽  
Author(s):  
Mark C. Bates ◽  
John E. Campbell ◽  
Patrick A. Stone ◽  
Michael R. Jaff ◽  
Mike Broce ◽  
...  

Thorax ◽  
1996 ◽  
Vol 51 (12) ◽  
pp. 1266-1269 ◽  
Author(s):  
K. al-Kattan ◽  
E. Sepsas ◽  
E. R. Townsend ◽  
S. W. Fountain

Sign in / Sign up

Export Citation Format

Share Document