scholarly journals Chylous Fistula following Axillary Lymphadenectomy: Benefit of Octreotide Treatment

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Elena González-Sánchez-Migallón ◽  
José Aguilar-Jiménez ◽  
José Andrés García-Marín ◽  
José Luis Aguayo-Albasini

Chyle leak following axillary lymph node clearance is a rare yet important complication. The treatment of postoperative chyle fistula still remains unclear. Conservative management is the first line of treatment. It includes axillary drains on continuous suction, pressure dressings, bed rest, and nutritional modifications. The use of somatostatin analogue is well documented as a treatment for chylous fistulas after neck surgery. We present a case of chylous fistula after axillary surgery resolved with the use of octreotide.

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Joshua Wong ◽  
Nicholas Farkas ◽  
Sherif Monib ◽  
Simon Thomson

Abstract Chyle leak following axillary lymph node clearance is a rarely reported complication. We present a case of chylous leakage following axillary lymph node clearance, which was diagnosed on clinical grounds. Surgical re-exploration was undertaken due to ongoing high output. However, the chylous leak recurred post-operatively, if at a lower rate. The patient was subsequently managed successfully with conservative measures, primarily utilizing regular aspiration and compression bandaging to the axilla.


2021 ◽  
Vol 14 (3) ◽  
pp. e236006
Author(s):  
Sylvie Bowden ◽  
Mohammed Firdouse ◽  
Graham Roche-Nagle

We present a patient who developed high output chyle leak post left transaxillary first rib resection for venous thoracic outlet syndrome. The high output chylorrhoea was successfully treated by conservative measures, bed rest, parenteral nutrition and low-fat diet. The patient was discharged after an 18-day hospital stay with a complete resolution of his chylous fistula prior to discharge. This is the first documented chylothorax post transaxillary first rib resection likely due to anomalous chyle anatomy.


Breast Care ◽  
2011 ◽  
Vol 6 (2) ◽  
pp. 130-132 ◽  
Author(s):  
John Taylor ◽  
Samira Jayasinghe ◽  
Ludger Barthelmes ◽  
Mike Chare

2011 ◽  
Vol 11 (5) ◽  
pp. 320-324 ◽  
Author(s):  
Mandeep Singh ◽  
S.V. Suryanarayana Deo ◽  
Nootan Kumar Shukla ◽  
Archit Pandit

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Ankita Sarawagi ◽  
Jessica Maxwell

Background. A female patient was diagnosed with a right-sided chyle leak following right skin sparing mastectomy, axillary lymph node dissection, and immediate tissue expander placement in the setting of invasive ductal carcinoma status post neoadjuvant chemotherapy. Summary. Our patient underwent a level I and II right axillary lymph node dissection followed by an axillary drain placement. On the first postoperative day, a change from serosanguinous to milky fluid in this drain was noted. The patient was diagnosed with a chyle leak based on the milky appearance and elevated triglyceride levels in the fluid. While chyle leaks are rare after an axillary dissection and even rarer to present on the right side, it is a complication of which breast surgeons should be aware. The cause of this complication is thought to be due to injury of the main thoracic duct, its branches, the subclavian duct, or its tributaries. Management is usually conservative; however, awareness of this potential complication even on the right side is of the utmost importance Conclusion. Chyle leaks are an uncommon complication of axillary node dissections and even rarer for them to present on the right side. It can be diagnosed by monitoring the drainage for changes in appearance and volume and by conducting supporting laboratory tests. Conservative management is generally suggested.


2014 ◽  
Vol 92 (1) ◽  
pp. 55-56
Author(s):  
Erene V. Flores ◽  
Gonzalo de Castro ◽  
Enrique Casal ◽  
Constantino Sobrino

Author(s):  
Naweed Alzaman ◽  
Anastassios G Pittas ◽  
Miriam O'Leary ◽  
Lisa Ceglia

Summary Transient hypocalcemia after thyroidectomy is not uncommon and the risk increases with the extent of neck surgery. We report a case of severe and prolonged hypocalcemia after total thyroidectomy complicated by thoracic duct injury. Hypoparathyroidism and thoracic duct injury are potential complications following total thyroidectomy with extensive lymph node dissection. This case suggested that having both conditions may complicate treatment of hypoparathyroid-induced hypocalcemia by way of losses of calcium and vitamin D in the chyle leak. Learning points This report highlights chyle leak as an uncommon cause of prolonged hypocalcemia in patients who have undergone extensive neck surgery. Chyle has an electrolyte concentration similar to that of plasma. Medical treatment options for a chyle leak include fat-free oral diet or parenteral nutrition without oral intake, pharmacological treatment (primarily octreotide).


1990 ◽  
Vol 122 (3) ◽  
pp. 309-312 ◽  
Author(s):  
Peter A. van Liessum ◽  
Leon M. Swinkels ◽  
Gerlach F. Pieters ◽  
Alec A. Ross ◽  
Anthony G. Smals ◽  
...  

Abstract Serum samples from 13 patients with active acromegaly on long-term sc treatment with octreotide (SMS 201-995, 1-36 months, mean daily dose 285 μg) were taken 12 h after the injection of their regular evening doses. Octreotide assay was performed using 125I-Tyr-SMS and a polyclonal rabbit anti-serum. For assessment of antibody formation both serum coated charcoal adsorption (adsorption of free octreotide) and polyethylene glycol precipitation (precipitation of IgG complexes) were used. The mean binding percentage in the patients proved to be similar to that of 5 healthy volunteers (p>0.10). No specific binding was detected, whatever method used. No correlation was found between the binding percentages and octreotide serum levels, duration of octreotide treatment or daily octreotide dose (p>0.10). These results strongly suggest that clinically relevant endogenous antibody formation is not a frequent event during long-term sc treatment of acromegalic patients with octreotide.


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