scholarly journals Botulinum Toxin A for the Treatment of a Child with SUNCT Syndrome

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Yi Zhang ◽  
Haifeng Zhang ◽  
Ya-Jun Lian ◽  
Yun-Qing Ma ◽  
Nan-Chang Xie ◽  
...  

Background.Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) syndrome is an unusual cause of headache, mainly described in older adults, and is rare in children. Pain attacks may be severe, frequent, and prolonged. The therapeutic benefits of many drugs are disappointing.Patient and Methods.A 12-year-old boy suffered severe headache and toothache for 20 days. As treatment with nonsteroidal anti-inflammatory drugs, anticonvulsants, and steroids proved ineffective, he was treated with ipsilateral multisite subcutaneous injections of botulinum toxin A 70 U around the orbit, the temporal area, and the upper gum.Results.The pain had reduced in frequency and severity by the fourth day after treatment and had completely disappeared after 7 days. There were no side effects or recurrence during a subsequent 17-month follow-up period.Conclusion.Botulinum toxin A can be used to treat the first episode of SUNCT in children over the age of 12 years.

2019 ◽  
Vol 18 (1) ◽  
pp. 97-103
Author(s):  
Jiaojiao Zhong ◽  
Yu Lan ◽  
Shuying Fu ◽  
Jing Zhang ◽  
Sha Lu ◽  
...  

Chronic skin ulcer (CSU) often combines with a variety of refractory factors that respond poorly to routine treatments. Botulinum toxin A (BTX-A) can be injected subcutaneously to improve the local blood supply, to reduce pain, and to promote wound healing. At present, few reports have mentioned BTX-A injection for chronic skin ulcer treatment. We observed the effect of four cases that used BTX-A to treat CSU and provided a brief review of the literature. Four cases of CSUs with 4 different causes were treated with BTX-A injection (4 U/cm2). The specific operation is as follows: local, multipoint, cyclic, equidistant, and subcutaneous injections with a depth of 6 to 8 mm. The ulcer area was significantly reduced. Subsequently, the ulcer healed within 20 to 48 days. Botulinum toxin A is recommended as an important treatment for chronic skin ulcer that can improve healing of skin ulcers with various etiologies.


2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Shuang Li ◽  
Ya-Jun Lian ◽  
Yuan Chen ◽  
Hai-Feng Zhang ◽  
Yun-Qing Ma ◽  
...  

2007 ◽  
Vol 13 ◽  
pp. S66
Author(s):  
K. Kollewe ◽  
N. Buhr ◽  
K. Krampfl ◽  
R. Dengler ◽  
B. Mohammadi

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