scholarly journals Stability and Hopf Bifurcation Analysis in a Delayed Myc/E2F/miR-17-92 Network Involving Interlinked Positive and Negative Feedback Loops

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Guiyuan Wang ◽  
Zhuoqin Yang

MiR-17-92 plays an important role in regulating the levels of the Myc/E2F protein. In this paper, we consider a coupling network between Myc/E2F/miR-17-92 delayed negative feedback loop and Myc/E2F positive feedback loop described by a two-dimensional delay differential equation. Based on linear stability analysis and bifurcation theory, sufficient conditions for stability of equilibria and oscillatory behaviors via Hopf bifurcation are derived when choosing time delay as well as negative feedback strength associated with oscillations as bifurcation parameters, respectively. Furthermore, direction and stability of Hopf bifurcation of time delay are studied by using the normal form method and center manifold theorem. Finally, several numerical simulations are performed to verify the results we obtained.

2019 ◽  
Vol 2019 (1) ◽  
Author(s):  
Zizhen Zhang ◽  
Ruibin Wei ◽  
Wanjun Xia

AbstractIn this paper, we are concerned with a delayed smoking model in which the population is divided into five classes. Sufficient conditions guaranteeing the local stability and existence of Hopf bifurcation for the model are established by taking the time delay as a bifurcation parameter and employing the Routh–Hurwitz criteria. Furthermore, direction and stability of the Hopf bifurcation are investigated by applying the center manifold theorem and normal form theory. Finally, computer simulations are implemented to support the analytic results and to analyze the effects of some parameters on the dynamical behavior of the model.


2013 ◽  
Vol 2013 ◽  
pp. 1-11
Author(s):  
Gang Zhu ◽  
Junjie Wei

The dynamics of a coupled optoelectronic feedback loops are investigated. Depending on the coupling parameters and the feedback strength, the system exhibits synchronized asymptotically stable equilibrium and Hopf bifurcation. Employing the center manifold theorem and normal form method introduced by Hassard et al. (1981), we give an algorithm for determining the Hopf bifurcation properties.


2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Wanjun Xia ◽  
Soumen Kundu ◽  
Sarit Maitra

A delayed ecoepidemic model with ratio-dependent transmission rate has been proposed in this paper. Effects of the time delay due to the gestation of the predator are the main focus of our work. Sufficient conditions for local stability and existence of a Hopf bifurcation of the model are derived by regarding the time delay as the bifurcation parameter. Furthermore, properties of the Hopf bifurcation are investigated by using the normal form theory and the center manifold theorem. Finally, numerical simulations are carried out in order to validate our obtained theoretical results.


2012 ◽  
Vol 2012 ◽  
pp. 1-17 ◽  
Author(s):  
Shuang Guo ◽  
Weihua Jiang

A class of three-dimensional Gause-type predator-prey model with delay is considered. Firstly, a group of sufficient conditions for the existence of Hopf bifurcation is obtained via employing the polynomial theorem by analyzing the distribution of the roots of the associated characteristic equation. Secondly, the direction of the Hopf bifurcation and the stability of the bifurcated periodic solutions are determined by applying the normal form method and the center manifold theorem. Finally, some numerical simulations are carried out to illustrate the obtained results.


2017 ◽  
Vol 27 (14) ◽  
pp. 1750214 ◽  
Author(s):  
Tao Dong ◽  
Linmao Xia

In this paper, a type of reaction–diffusion neutral neuron system with time delay under homogeneous Neumann boundary conditions is considered. By constructing a basis of phase space based on the eigenvectors of the corresponding Laplace operator, the characteristic equation of this system is obtained. Then, by selecting time delay and self-feedback strength as the bifurcating parameters respectively, the dynamic behaviors including local stability and Hopf bifurcation near the zero equilibrium point are investigated when the time delay and self-feedback strength vary. Furthermore, the direction of the Hopf bifurcation and the stability of bifurcating periodic solutions are obtained by using the normal form and the center manifold theorem for the corresponding partial differential equation. Finally, two simulation examples are given to verify the theory.


2021 ◽  
Vol 2021 ◽  
pp. 1-18
Author(s):  
Yanxia Zhang ◽  
Long Li ◽  
Junjian Huang ◽  
Yanjun Liu

In this paper, a vector-borne disease model with two delays and reinfection is established and considered. First of all, the existence of the equilibrium of the system, under different cases of two delays, is discussed through analyzing the corresponding characteristic equation of the linear system. Some conditions that the system undergoes Hopf bifurcation at the endemic equilibrium are obtained. Furthermore, by employing the normal form method and the center manifold theorem for delay differential equations, some explicit formulas used to describe the properties of bifurcating periodic solutions are derived. Finally, the numerical examples and simulations are presented to verify our theoretical conclusions. Meanwhile, the influences of the degree of partial protection for recovered people acquired by a primary infection on the endemic equilibrium and the critical values of the two delays are analyzed.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Juan Liu

A delayed SEIQRS model for the transmission of malicious objects in computer network is considered in this paper. Local stability of the positive equilibrium of the model and existence of local Hopf bifurcation are investigated by regarding the time delay due to the temporary immunity period after which a recovered computer may be infected again. Further, the properties of the Hopf bifurcation are studied by using the normal form method and center manifold theorem. Numerical simulations are also presented to support the theoretical results.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Zizhen Zhang ◽  
Yougang Wang ◽  
Luca Guerrini

This paper is concerned with a delayed SVEIR worm propagation model with saturated incidence. The main objective is to investigate the effect of the time delay on the model. Sufficient conditions for local stability of the positive equilibrium and existence of a Hopf bifurcation are obtained by choosing the time delay as the bifurcation parameter. Particularly, explicit formulas determining direction of the Hopf bifurcation and stability of the bifurcating periodic solutions are derived by using the normal form theory and the center manifold theorem. Numerical simulations for a set of parameter values are carried out to illustrate the analytical results.


2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Chunming Zhang ◽  
Wanping Liu ◽  
Jing Xiao ◽  
Yun Zhao

A model applicable to describe the propagation of computer virus is developed and studied, along with the latent time incorporated. We regard time delay as a bifurcating parameter to study the dynamical behaviors including local asymptotical stability and local Hopf bifurcation. By analyzing the associated characteristic equation, Hopf bifurcation occurs when the time delay passes through a sequence of critical values. A formula for determining the direction of the Hopf bifurcation and the stability of bifurcating periodic solutions is given by using the normal form method and center manifold theorem. Finally, illustrative examples are given to support the theoretical results.


2009 ◽  
Vol 2009 ◽  
pp. 1-20
Author(s):  
Xiaoqian Cui ◽  
Junjie Wei

A kind of fourth-order delay differential equation is considered. Firstly, the linear stability is investigated by analyzing the associated characteristic equation. It is found that there are stability switches for time delay and Hopf bifurcations when time delay cross through some critical values. Then the direction and stability of the Hopf bifurcation are determined, using the normal form method and the center manifold theorem. Finally, some numerical simulations are carried out to illustrate the analytic results.


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