scholarly journals Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Elena Mantovani ◽  
Stefano Busani ◽  
Emanuela Biagioni ◽  
Claudia Venturelli ◽  
Lucia Serio ◽  
...  

Primary infection by Capnocytophaga canimorsus after dog bite is rare but may be difficult to identify and rapidly lethal. We describe a case of fatal septic shock with fulminant purpura occurred in a patient without specific risk factor two days after an irrelevant dog bite. The patient was brought to hospital because of altered mental status, fever, and abdominal pain. In a few hours patient became hypoxic and cyanotic. The patient became extremely hypotensive with shock refractory to an aggressive fluid resuscitation (40 ml/kg crystalloids). She received vasoactive drugs, antibiotic therapy, and blood purification treatment, but cardiac arrest unresponsive to resuscitation maneuvers occurred. Case description and literature review demonstrated that, also in patients without specific risk factors, signs of infection after dog bite should be never underestimated and should be treated with a prompt antibiotic therapy initiation even before occurrence of organ dysfunction.

Medicine ◽  
1991 ◽  
Vol 70 (5) ◽  
pp. 287-292 ◽  
Author(s):  
BART-JAN KULLBERG ◽  
RUDI G. J. WESTENDORP ◽  
JAN W. VANʼT WOUT ◽  
A. Edo Meinders

2012 ◽  
Vol 44 (8) ◽  
pp. 635-639 ◽  
Author(s):  
Claus Behrend Christiansen ◽  
Ronan M. G. Berg ◽  
Ronni R. Plovsing ◽  
Kirsten Møller

Author(s):  
Stefano Busani ◽  
Erika Roat ◽  
Giulia Serafini ◽  
Elena Mantovani ◽  
Emanuela Biagioni ◽  
...  

Patients with septic shock by multidrug resistant microorganisms (MDR) are a specific sepsis population with a high mortality risk. The exposure to an initial inappropriate empiric antibiotic therapy has been considered responsible for the increased mortality, although other factors such as immune-paralysis seem to play a pivotal role. Therefore, beyond conventional early antibiotic therapy and fluid resuscitation, this population may benefit from the use of alternative strategies aimed at supporting the immune system. In this review we present an overview of the relationship between MDR infections and immune response and focus on the rationale and the clinical data available on the possible adjunctive immunotherapies, including blood purification techniques and different pharmacological approaches.


Cureus ◽  
2021 ◽  
Author(s):  
Michelle-Ashley Rizk ◽  
Nicholas Abourizk ◽  
Kinjal P Gadhiya ◽  
Panupong Hansrivijit ◽  
John D Goldman

Author(s):  
Seweryn Bialasiewicz ◽  
Tania P.S. Duarte ◽  
Son H. Nguyen ◽  
Vichitra Sukumaran ◽  
Alexandra Stewart ◽  
...  

We present a case of Capnocytophaga canimorsus septic shock after a dog bite in an immunocompetent individual, where real-time nanopore metagenomic sequencing characterized the microbial agent within 19 hours, with subsequent confirmation using droplet digital PCR. Oral swabs from the dog demonstrated a nearly-identical C. canimorsus isolate by sequencing.


2020 ◽  
Vol 7 (2) ◽  
pp. 22
Author(s):  
Peter Anderyas ◽  
Julia Freckelton ◽  
James J Gome ◽  
Satish Nagarajah ◽  
Nuwan Dhanushka Miththinda Jasenthu Kankanamage

Capnocytophaga canimorsus is a commensal in the normal gingival flora of canine and feline species and is reported to cause infections in humans following bites by these species with potentially serious consequences, especially in the immunocompromised. Here we report a case of a 58-year-old healthy woman presenting with uncomplicated meningitis following a seemingly minor bite by her pet dog. With early detection and appropriate antibiotic therapy she had an uneventful recovery. Our case reports the possibility of this organism infecting an otherwise healthy, immunocompetent adult and the importance of being vigilant of such rare presentations by clinicians which will help to deliver appropriate therapy early to avoid any serious complications.


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