scholarly journals Severe Hypermagnesemia with Normal Renal Function Can Improve with Symptomatic Treatment

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Yoshiaki Ishida ◽  
Akihiko Tabuchi
Keyword(s):  
Renal Function ◽  
Normal Renal Function ◽  
Supportive Therapy ◽  
High Volume ◽  
Symptomatic Treatment ◽  
Bowel Distension ◽  
Level Of Consciousness ◽  
History Of ◽  
Biochemical Testing ◽  
Tendon Reflexes

Hypermagnesemia is a rare disorder and commonly occurs in patients with renal dysfunction. Supportive therapy for hypermagnesemia consists of administration of high-volume fluids, calcium preparation, diuretics, and, in severe cases, hemodialysis. Few reports have described severe hypermagnesemia patients with normal renal function who improved without hemodialysis. A 56-year-old woman presented with a history of constipation in spite of taking constipation medicine, including MgO. She was brought to our emergency department due to vomiting and diffuse distension of the abdomen. Sudden vomiting, weakness, and lower level of consciousness occurred during examination. Her blood pressure dropped to 77/34 mmHg, and deep tendon reflexes of the limbs disappeared. Abdominal computed tomography showed bowel distension with wall edema, and biochemical testing showed serum Mg at 13.5 mg/dl. She was diagnosed with severe hypermagnesemia associated with intestinal obstruction and administered intravenous loop diuretics and calcium preparation in addition to high volumes of normal saline. As the serum Mg level steadily declined, her level of consciousness returned to usual. This case suggests that severe hypermagnesemia can occur in patients with normal renal function and constipation under MgO. Severe hypermagnesemia with normal renal function can improve with symptomatic treatment without hemodialysis.

scholarly journals Hypermagnesemia in a 20-month-old healthy girl caused by the use of a laxative: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Kotaro Araki ◽  
Yuhei Kawashima ◽  
Miyuki Magota ◽  
Norio Shishida
Keyword(s):  
Emergency Department ◽  
Renal Function ◽  
Renal Dysfunction ◽  
Impaired Renal Function ◽  
Muscle Tone ◽  
Case Presentation ◽  
Cardiac Side Effects ◽  
Level Of Consciousness ◽  
Tendon Reflexes

Abstract Background Hypermagnesemia can be a fatal condition and should be diagnosed early on. Most reports of hypermagnesemia have been of adults with impaired renal function. We describe the case of a pediatric patient without renal dysfunction who developed severe hypermagnesemia. Case presentation A healthy 20-month-old Asian girl presented to our emergency department with episodes of vomiting and a reduced level of consciousness. The neurological examination showed a symmetric decrease in muscle tone, and the deep tendon reflexes were decreased. On admission, her magnesium (Mg) level was 11.0 mg/dL after receiving magnesium oxide for 4 days because of constipation. She was immediately administered calcium gluconate infusion (3.9 mEq), and then was continuously infused with it (0.23 mEq/h) as a Mg antagonist to cardiac side effects. She was kept hydrated with 0.9% sodium chloride to maintain good urine output to excrete the Mg. The level of the serum Mg decreased to 2.4 mg/dL, enabling her to regain consciousness. During 5 years of follow-up, she was neurologically well, without the recurrence of hypermagnesemia. Conclusions Even in the absence of significant renal dysfunction, the prescription of a laxative containing Mg for constipation can result in severe hypermagnesemia. In addition, the symptoms of hypermagnesemia are nonspecific, and early diagnosis is difficult unless it is actively suspected.

Acute kidney injury associated with ingestion of star fruit: Acute oxalate nephropathy: a report of two cases

2019 ◽  
Vol 8 (2) ◽  
pp. 47-51
Author(s):  
Mahmud Javed Hasan ◽  
Nitai Chandra Ray ◽  
Shaikh Shariful Islam ◽  
Shakil Azam Nahid ◽  
Tumpa Shom ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Normal Renal Function ◽  
Herbal Remedy ◽  
Case Reports ◽  
Kidney Injury ◽  
Young Male ◽  
Empty Stomach ◽  
Star Fruit ◽  
History Of

There are few case reports regarding star fruit's nephrotoxicity and neurotoxicity in chronic kidney disease patients. Star fruit (Averrhoa carambola) is commonly consumed as a herbal remedy for various ailments in tropical countries. However, the dangers associated with consumption of star fruit are not commonly known. Although star fruit induced oxalate nephrotoxicity in those with existing renal impairment is well documented, reports on its effect on those with normal renal function are infrequent. We report two unique clinical presentation patterns of star fruit nephrotoxicity following consumption of the fruit. The first patient is a 52 year-old male diabetic patient who had normal renal function prior to developing acute kidney injury (AKI) after consuming large amount of star fruit juice at once for remedy of diabetes. The second patient, a 27 years old young male who developed acute kidney injury following star fruit ingestion in empty stomach. One case needed 4 sessions of hemodialysis another case recovered over 2 weeks without the need for haemodialysis. Consumption of star fruit, especially on an empty stomach or in a state of dehydration may precipitate acute kidney injury. A history of star fruit ingestion must be actively looked for in patients presenting with unexplained acute kidney injury. The use of star fruit as a therapy for diabetes should be discouraged. CBMJ 2019 July: Vol. 08 No. 02 P: 47-51

scholarly journals Nephrogenic Diabetes Insipidus (NDI): a Rare Presentation in Early Infancy- A Case Report

2014 ◽  
Vol 41 (1) ◽  
pp. 62-63
Author(s):  
M Akteruzzaman ◽  
Z Islam ◽  
S Afroza ◽  
ARML Kabir ◽  
SK Paul ◽  
...  
Keyword(s):  
Medical Journal ◽  
Renal Function ◽  
Case Report ◽  
Family History ◽  
Urinary Bladder ◽  
Normal Renal Function ◽  
Nephrogenic Diabetes Insipidus ◽  
Water Deprivation ◽  
Rare Presentation ◽  
History Of

A 30 months old boy presented with polyuria and polydipsia since 6 months of age. There was no family history of similar illness. Investigations revealed serum hyperosmolarity and normal renal function. Diagnostic findings correlated with nephrogenic diabetis insipidus (NDI) as the patient was non-responsive to vasopressin in water deprivation test. MRI of brain was normal and ultrasonogram of kidney, ureter, and urinary bladder was normal and other investigations showed no abnormality. DOI: http://dx.doi.org/10.3329/bmj.v41i1.18788 Bangladesh Medical Journal 2012 Vol. 41 No. 1; 62-63

ACTION ON MATTER: THE HISTORY OF THE UNIQUELY AFRICAN TAMPER AND CONCAVE ANVIL POT-FORMING TECHNIQUE

2003 ◽  
Vol 1 (1) ◽  
pp. 3-35 ◽  
Author(s):  
Judy Sterner ◽  
Nicholas David
Keyword(s):  
Historical Development ◽  
Weight Ratio ◽  
High Volume ◽  
Efficient Production ◽  
Arid Environments ◽  
Historical Evidence ◽  
Culture History ◽  
History Of ◽  
And Diffusion

The publication, largely by ethnoarchaeologists, of new data on the tamper and concave anvil technique of pot-forming (TCA) permits a reassessment of this uniquely African technique, its toolkit, and its culture history. A survey, inspired by the technologie culturelle school, of its varied expressions in the southern Saharan, Sahelian and northern Sudan zones from Mali to Sudan and extending north into Egypt emphasises the potential of the technique for the efficient production of spherical water jars of high volume to weight ratio, much appreciated in arid environments. The technique is demanding and therefore practised for the most part by specialists. The origins and diffusion of the technique are assessed in the light of the ethnological, archaeological, linguistic, and historical evidence, and a four stage historical development is sketched.

Stapled Surgery for Hemorrhoidal Prolapse: From the Beginning to the Modern Times

2020 ◽  
Vol 15 ◽  
Author(s):  
Alessandro Sturiale ◽  
Bernardina Fabiani ◽  
Claudia Menconi ◽  
Danilo Cafaro ◽  
Felipe Celedon Porzio ◽  
...  
Keyword(s):  
Postoperative Bleeding ◽  
Invasive Procedure ◽  
High Volume ◽  
Normal Mucosa ◽  
Stapled Hemorrhoidopexy ◽  
Wound Complications ◽  
Rectal Intussusception ◽  
Stapler Technique ◽  
History Of ◽  
Hemorrhoidal Prolapse

Introduction: Hemorrhoidal disease is the most common proctologic condition in adults. Among the different surgical procedures, one of the greatest innovations is represented by the stapled hemorrhoidopexy. The history of this technique started with a single stapler use passing thorough a double stapler technique to resect the adequate amount of prolapse, finally arriving to the use of high volume devices. Methods: Nevertheless each device has its own specific feature, the stapler is basically made up with one or more circular lines of titanium staples whose height may be variable. The procedure is based on different steps: Introduction of the CAD, evaluation of the prolapse, fashioning purse string or parachute suture, introduction of the stapler head beyond the suture, pull the wires through the window, close the stapler and keep pulled the wires of the suture held together with a forcep, fire using two hands, open the stapler and remove it and check the staple line and then check the specimen. One of the latest innovations in stapled surgery the Tissue Selective Therapy. It is a minimally invasive procedure in which there is a partial circular stapled hemorrhoidopexy focused on the prolapsing piles with bridges of normal mucosa left. Results: Several studies have reported that SH is a safe and effective procedure to treat the hemorrhoidal prolapse. It is a quicker procedure with a shorter hospital stay and earlier return to work if compared with the conventional treatment. This is due to a less postoperative pain, postoperative bleeding, wound complications and constipation. Furthermore, the first generation devices had worse outcomes if compared with those of the new generation stapler that showed lower postoperative complication rate with better anatomical and symptomatic results. Conclusions: Stapled procedure for the treatment of symptomatic hemorrhoidal prolapse represents one of the most important innovations in proctology of the last century bringing with it the new revolutionary concept of the rectal intussusception as a determining factor involved in the natural history of the disease. Stapled hemorrhoidopexy marked an era in which the surgeon may to offer to the patients a safe, effective treatment with less pain and fast recovery.

scholarly journals Periodontal disease characterization in dogs with normal renal function or chronic renal failure

2004 ◽  
Vol 34 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Glenda Ramalho Barbudo-Selmi ◽  
Marileda Bonafim Carvalho ◽  
André Luis Selmi ◽  
Silvio Emílio Cuevas Martins
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Chronic Renal Failure ◽  
Periodontal Disease ◽  
Normal Renal Function ◽  
White Blood Cells ◽  
Gingival Recession ◽  
Plaque Index ◽  
Urine Specific Gravity ◽  
Bacterial Plaque

The purpose of this study was to evaluate periodontal disease (PD) in dogs with chronic renal failure (CRF) and to compare it to PD in dogs with normal renal function (NRF). Twelve dogs with CRF and 24 dogs with NRF, all presenting dental pocket formation, were compared. In all dogs, serum creatinine, blood urea nitrogen, urine specific gravity and total red and white blood cells were determined. A complete oral examination was also performed including evaluation of bacterial plaque, gingivitis, gingival recession, pocket, calculus, dental mobility, dental loss, and ulcers. These data were used to calculate plaque index (PI), gingival index (GI) and periodontal destruction index (PDI). PD was graded as mild, moderate or severe based on the results. Mild, moderate or severe PD was observed in dogs with NRF, whereas dogs with CRF presented either mild or severe PD. Dogs with NRF showed higher involvement of the maxillary teeth, whereas dogs with CRF showed a higher involvement of the mandibular teeth. Plaque index was significantly higher in dogs with NRF. It was concluded that lesion distribution and periodontal disease progression may be altered in dogs with CRF, and gingival inflammatory response differs in dogs with NRF and CRF regarding to the stage of periodontal disease.

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